Gene Information

Name : guaA (SMU_1066)
Accession : NP_721458.1
Strain : Streptococcus mutans UA159
Genome accession: NC_004350
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1010105 - 1011658 bp
Length : 1554 bp
Strand : +
Note : Best Blastp Hit: gb|AAD15805.1| (AF058326) GMP synthase [Lactococcus lactis]

DNA sequence :
ATGACTGATATTAAAGATATTCAAAAAATTATCGTACTTGACTACGGCAGTCAGTACAATCAGCTGATCGCACGCCGCAT
TCGTGAATTTGGTATTTTTTCTGAATTGAGAAGCCATAAGGTAACAGCCGACGAAGTCCGTGCTATCAATCCAATTGGTA
TTGTCCTTTCAGGAGGACCAAGTTCAGTTTATGCTGAAGATGCCTTTGACATTGATAAGGAAATCCTTGATCTTGGAATC
CCCGTTTTAGGTATTTGTTATGGTATGCAGCTTCTTACAGAAAAACTTGGCGGTAAAGTTGTTCCTGCTGGACAAACTGG
CAATAGTGAATATGGTCAGTCTACACTTCATTTGACAGAAAACTCAGAGCTTTTTAAGGAAACTCCTGCTGAACAAACTG
TTTTGATGAGCCATGGCGATGCTGTTACTGAAATTCCCGAAGGCTTTCAATTGGTTGGCAAATCAAGCGACTGCCCTTAT
GCTGCCATTGAAAATGTCGAAAAGAAAATCTTTGGCATTCAATTTCACCCAGAAGTTCGTCATACGGAATATGGTAATGC
GATTTTACGCAATTTTGCTTTTAATGTTTGTAAAGCCAAAGGTGATTGGTCAATGGACAGTTTCATTGATATGGAAATTG
AAAAAATCCGTGAACAAGTTGGTAATCGTAAGGTTCTTCTGGGGCTTTCGGGCGGTGTGGACTCTTCTGTTGTTGGCGTG
CTTTTGCAAAAAGCTATAGGTGACCAATTAACCTGTATCTTCGTTGATCATGGCCTTCTTCGTAAGGGTGAAGGCGATCA
GGTTATGGAAATGTTGGGTGGTAGATTTGGACTCAATATTATTCGTGTTGATGCTTCCAAACGCTTTTTGGATCTTCTTG
CTGGTATTGATGATCCTGAGAAAAAGCGTAAAATCATTGGGAATGAATTTGTCTATGTTTTTGATGATGAAGCCAGCAAA
CAAAAAGGCGTTGATTTCTTGGCACAAGGAACGCTTTATACAGATGTCATCGAATCCGGCACAGAAACAGCCCAAACCAT
TAAATCACACCACAATGTCGGTGGTCTTCCAGAAGACATGCAGTTTGAATTAATAGAGCCGTTAAACACACTGTTCAAGG
ATGAAGTTCGTACTCTGGGGACTGCTTTAGGAATGCCAGATGAAATCGTTTGGCGGCAACCATTTCCAGGACCTGGACTT
GCCATTCGGGTGATGGGAGAAATTACTGCTGAAAAACTTGAAACGGTTCGTGAATCTGACGCTATTTTACGCGAAGAAAT
TGCTGCAGCAGGCCTGAATCGTGATATTTGGCAATATTTTACTGTCAATACTGGCGTTCGTTCAGTCGGAGTTATGGGAG
ATGGTCGTACCTATGACTATACCATCGCTATTCGCGCCATCACTTCTATTGACGGCATGACAGCAGACTTTGCCCGTATT
CCTTGGGAGGTTCTCCAAAAGATCTCTGTTCGTATTGTCAACGAAGTGGAACACGTCAACCGCATCGTCTACGACATTAC
CAGCAAACCACCAGCAACTGTTGAGTGGGAATAA

Protein sequence :
MTDIKDIQKIIVLDYGSQYNQLIARRIREFGIFSELRSHKVTADEVRAINPIGIVLSGGPSSVYAEDAFDIDKEILDLGI
PVLGICYGMQLLTEKLGGKVVPAGQTGNSEYGQSTLHLTENSELFKETPAEQTVLMSHGDAVTEIPEGFQLVGKSSDCPY
AAIENVEKKIFGIQFHPEVRHTEYGNAILRNFAFNVCKAKGDWSMDSFIDMEIEKIREQVGNRKVLLGLSGGVDSSVVGV
LLQKAIGDQLTCIFVDHGLLRKGEGDQVMEMLGGRFGLNIIRVDASKRFLDLLAGIDDPEKKRKIIGNEFVYVFDDEASK
QKGVDFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRTLGTALGMPDEIVWRQPFPGPGL
AIRVMGEITAEKLETVRESDAILREEIAAAGLNRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFARI
PWEVLQKISVRIVNEVEHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-174 70
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-174 70
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-174 70
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-120 51