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Name : blaA (SO_0837) Accession : NP_716468.1 Strain : Shewanella oneidensis MR-1 Genome accession: NC_004347 Putative virulence/resistance : Resistance Product : class D carbapenem-hydrolyzing beta-lactamase BlaA Function : - COG functional category : V : Defense mechanisms COG ID : COG2602 EC number : 3.5.2.6 Position : 854515 - 855312 bp Length : 798 bp Strand : + Note : - DNA sequence : ATGCGTGTGTTAGCCTTATCGGCTGTATTAGTGGTGGCATCGATTGTTGGCATGCCGGCGATGGCAAACGAATGGCAGGA AAAACCGAGTTGGAATACTCATTTTTCGGAACATAAAGCGCAGGGTGTGATAGTGCTTTGGAACGAGAACAAACAGCAAG GATTTACCAATAATCTTAAGCGGGCAAACCAAGCATTTTTACCCGCATCGACCTTTAAAATCCCCAATAGCTTGATTGCC TTGGATTTAGGTGTCGTGAAGGATGAGCATCAAGTCTTTAAATGGGATGGACAGACTCGGGATATCGCGGCGTGGAATCG CGACCATGACTTAATCACTGCGATGAAATACTCGGTCGTGCCCGTGTATCAAGAGTTTGCGCGCCAAATTGGGCAGGCGC GCATGAGTAAAATGTTGCACGCATTTGATTATGGCAATGAAGATATTTCGGGCAATCTAGACAGCTTTTGGCTCGATGGC GGCATTCGGATTTCGGCAACGGAGCAAGTCGCATTTCTACGAAAGCTGTATCATAACAAGTTGCATGTATCAGAACGCAG TCAGCGTATCGTCAAGCAAGCCATGCTTACCGAGGCTAATAGTGACTACATAATCCGCGCTAAAACCGGATACTCGACCA GAATTGAGCCTCAGATCGGTTGGTGGGTCGGTTGGGTTGAACTCGATGATAATGTGTGGTTCTTCGCGATGAATATGGAT ATGCCTACGGCTGATGGTTTAGGGCTACGTCAAGCCATCACTAAAGAAGTGCTTAAACAGGAAAAGATAATTCCATAG Protein sequence : MRVLALSAVLVVASIVGMPAMANEWQEKPSWNTHFSEHKAQGVIVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIA LDLGVVKDEHQVFKWDGQTRDIAAWNRDHDLITAMKYSVVPVYQEFARQIGQARMSKMLHAFDYGNEDISGNLDSFWLDG GIRISATEQVAFLRKLYHNKLHVSERSQRIVKQAMLTEANSDYIIRAKTGYSTRIEPQIGWWVGWVELDDNVWFFAMNMD MPTADGLGLRQAITKEVLKQEKIIP |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| bla OXA-10 | CAJ77047.1 | Oxacillinase | Not tested | AbaR1 | Protein | 3e-60 | 48 |
| blaOXA-129 | AET25386.1 | OXA-129 beta-lactamase | Not tested | PAGI-2(C) | Protein | 3e-56 | 47 |
| bla OXA-129 | AFG30109.1 | OXA-129 beta-lactamase | Not tested | PAGI-2 | Protein | 3e-56 | 47 |
| blaOXA-2 | YP_005176242.1 | beta-lactamase OXA-2 protein | Not tested | ICEPmu1 | Protein | 5e-41 | 44 |
| ACICU_00226 | YP_001844885.1 | Beta-lactamase class D | Not tested | AbaR20 | Protein | 8e-42 | 43 |
| oxa-23 | AFV47968.1 | class D beta-lactamase OXA-23 | Not tested | AbaR25 | Protein | 1e-40 | 41 |
| oxa-23 | AFV47996.1 | class D beta-lactamase OXA-23 | Not tested | delta-AbaR25 | Protein | 1e-40 | 41 |
| BJAB0715_00989 | YP_008216137.1 | Beta-lactamase class D | Not tested | AbaR27 | Protein | 1e-40 | 41 |
| oxa23 | AEO37447.1 | class D beta-lactamase OXA-23 | Not tested | AbaR4 | Protein | 1e-40 | 41 |
| bla(Oxa-23) | AFH57213.1 | carbapenemase | Not tested | AbaR4b | Protein | 1e-40 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AY500137.1.gene1.p01 | Protein | 1e-115 | 100 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | JN205800.1.gene6.p01 | Protein | 8e-112 | 94 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | HM015773.1.gene6.p01 | Protein | 1e-111 | 93 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | HQ700343.1.gene1.p01 | Protein | 5e-108 | 91 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AY343493.1.gene1.p01 | Protein | 1e-72 | 59 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | X75562.1.gene1.p01 | Protein | 5e-57 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AJ854182.1.gene1.p01 | Protein | 5e-60 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | U37105.2.gene2.p01 | Protein | 2e-60 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AM412777.1.gene1.p01 | Protein | 2e-59 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | Z22590.1.gene1.p01 | Protein | 9e-60 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | U59183.1.gene3.p01 | Protein | 5e-60 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | NC_010410.6002874.p0 | Protein | 2e-60 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AF231133.1.gene3.p01 | Protein | 9e-59 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AY445080.1.gene1.p01 | Protein | 2e-59 | 48 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | X58272.1.gene1.p01 | Protein | 2e-56 | 47 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AM932669.1.gene2.p01 | Protein | 2e-56 | 47 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AF300985.1.gene1.p01 | Protein | 1e-39 | 45 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AF350424.1.gene1.p01 | Protein | 2e-38 | 45 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | L07945.1.gene1.p01 | Protein | 8e-42 | 45 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AF315351.1.gene2.p01 | Protein | 1e-41 | 45 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AF371964.1.gene1.p1 | Protein | 4e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AY139598.1.gene3.p01 | Protein | 1e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AF317511.1.gene5.p01 | Protein | 8e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | JF800667.1.gene2.p01 | Protein | 2e-40 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | Y10693.2.gene1.p2 | Protein | 1e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | DQ522237.1.gene5.p01 | Protein | 1e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | M95287.gene.p01 | Protein | 2e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | JF795487.1.gene1.p01 | Protein | 2e-40 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | U63835.1.gene1.p01 | Protein | 5e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | GQ202693.1.gene2.p01 | Protein | 3e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | EF552405.1.gene1.p01 | Protein | 5e-41 | 44 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AF024602.1.gene3.p01 | Protein | 4e-42 | 43 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AY289608.1.gene2.p01 | Protein | 1e-40 | 43 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | EU086830.1.gene1.p01 | Protein | 4e-35 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | EU086834.1.gene1.p01 | Protein | 6e-35 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | JF273470.1.gene1.p01 | Protein | 2e-35 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AY288523.1.gene1.p01 | Protein | 2e-40 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | FJ194494.1.gene1.p01 | Protein | 3e-40 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | HM488991.1.gene1.p1 | Protein | 9e-41 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | HM488989.1.gene1.p1 | Protein | 6e-41 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | NC_011586.7044972.p0 | Protein | 6e-41 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | HM488990.1.gene1.p1 | Protein | 5e-41 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | AY795964.gene.p01 | Protein | 6e-41 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | HM488992.1.gene1.p1 | Protein | 2e-40 | 41 |
| blaA | NP_716468.1 | class D carbapenem-hydrolyzing beta-lactamase BlaA | HM488988.1.gene1.p1 | Protein | 5e-41 | 41 |
