Gene Information

Name : exaC (SO_4480)
Accession : NP_720001.1
Strain : Shewanella oneidensis MR-1
Genome accession: NC_004347
Putative virulence/resistance : Virulence
Product : NAD+-dependent acetaldehyde dehydrogenase ExaC
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 4669480 - 4671000 bp
Length : 1521 bp
Strand : +
Note : -

DNA sequence :
ATGATTTATGCTCAACCCGGAACCGCAGGTGCACTCGTAAATTTTAAAGAAAAATACGCCAACTTTATCGGTGGCAAATG
GGTCGCCCCAGTCAACGGCAAATACTTCGATAATCGCTCCCCCGTCAACGGGCAAAACTTCTGTAAAATTCCCCGCTCCG
ATGCACAAGATATTGAACTGGCACTCGATGCTGCCCACGCAGCCAAAGACGCTTGGGGCAAAACCTCGGTTACCGAGCGC
TCAAATATACTGCTGCGCATCGCCGATCGCGTTGAGCAAAATCTCGAGTACTTAGCGGTTGCCGAAACCTGGGAAAACGG
CAAAGCCGTGCGTGAAACTCTCAATGCCGACTTACCATTATTTGTGGATCATTTCCGCTATTTCGCTGGCTGTATTCGAG
CGCAGGAAGGTAGCGCCGCGGATATTGATGGCAACACTGTGAGTTATCACTTTCCTGAGCCTTTAGGTGTGGTCGGGCAA
ATCATCCCGTGGAACTTCCCGCTATTAATGGCAGCATGGAAAATCGCCCCCGCCTTAGCCGCAGGTAACTGTGTGGTGCT
CAAACCCGCCGAGCAAACGCCCGTATCTATTCTTGTGCTGCTCGAACTGATTGAAGATCTGCTGCCGCCCGGCGTACTTA
ACGTCGTCAACGGTTTTGGCGCCGAAGCGGGCCAAGCCCTCGCCACCAGCAAACGTATCGCTAAACTGGCCTTTACTGGC
TCCACCGAAGTGGGTTTTCACATCTTAAAATGCGCCGCCGAATCGCTTATCCCCTCTACCGTCGAACTCGGCGGTAAATC
GCCAAACCTGTATTTTGCCGATGTGATGGATCAAGAAGACGAATACTTAGATAAGGCCGTCGAAGGCATGTTGCTAGCTT
TCTTCAACCAAGGTGAAGTCTGTACTTGCCCATCACGGGTGCTGATCCAAGAATCGATTTACGATCGCTTTATCGAAAAA
GTCCTCGCCCGTGCGCAAACGATCAAGCAGGGTAACCCGCTGGATACCGCAACCCAAGTCGGCGCTCAAGCCTCCCAAGA
ACAATTCGATAAAATCTTAAGCTATCTCGCAATTGGTAAAGATGAAGGCGCACAGGTGCTCTTAGGTGGCTCACTCTGCC
AACTCGAAGGCGAGCAAAGCAAAGGCTATTACATCAGCCCAACGATTATGAAGGGCCATAATAAGATGCGGATTTTCCAA
GAGGAAATCTTCGGTCCGGTTATTTCGGTCACCACCTTTAAGGATGAAGCCGAAGCTTTAGCGATCGCCAACGACACTGA
ATATGGCCTAGGCGCAGGTGTGTGGACGCGGGATATGAACCGCGCCCAACGTATGGGCAGAGGTATTCAGGCTGGTCGTG
TTTGGATTAACTGCTACCATGCTTATCCTGCCCATGCGGCCTTTGGCGGTTATAAGAAGTCAGGCATCGGCCGTGAAACC
CACAAGATGATGCTCAATCACTACCAAAACACCAAAAACCTGTTGGTCAGCTACGATATCAATCCGCTCGGTTTCTTCTA
A

Protein sequence :
MIYAQPGTAGALVNFKEKYANFIGGKWVAPVNGKYFDNRSPVNGQNFCKIPRSDAQDIELALDAAHAAKDAWGKTSVTER
SNILLRIADRVEQNLEYLAVAETWENGKAVRETLNADLPLFVDHFRYFAGCIRAQEGSAADIDGNTVSYHFPEPLGVVGQ
IIPWNFPLLMAAWKIAPALAAGNCVVLKPAEQTPVSILVLLELIEDLLPPGVLNVVNGFGAEAGQALATSKRIAKLAFTG
STEVGFHILKCAAESLIPSTVELGGKSPNLYFADVMDQEDEYLDKAVEGMLLAFFNQGEVCTCPSRVLIQESIYDRFIEK
VLARAQTIKQGNPLDTATQVGAQASQEQFDKILSYLAIGKDEGAQVLLGGSLCQLEGEQSKGYYISPTIMKGHNKMRIFQ
EEIFGPVISVTTFKDEAEALAIANDTEYGLGAGVWTRDMNRAQRMGRGIQAGRVWINCYHAYPAHAAFGGYKKSGIGRET
HKMMLNHYQNTKNLLVSYDINPLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-164 71
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-173 70
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-173 70
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-173 70
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-172 70

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
exaC NP_720001.1 NAD+-dependent acetaldehyde dehydrogenase ExaC VFG0082 Protein 6e-165 71