Gene Information

Name : nrdE (WGLp610)
Accession : NP_871613.1
Strain : Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Genome accession: NC_004344
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 694843 - 696957 bp
Length : 2115 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGCATAAAATAGATTATCATGCACTTAATGCTATGTTAAATCTTTATGATAAAAACGGTCTTTTGCAAATAGAAAAAGA
TGTTTTTGCAATAAATAGTTATTATGAACAACATGTATTACCAAATAAAAAAAAATTTTCTTCTTTGGAAGATCGTATAA
CATACTTATTGAAAGAAGAATATTACGAGTCTAATGTTTTTGAAAATTACAAAAAGGATTTCATAAAAAATATTTTTTTT
CAAAGCAAGAAACAAGGATTTAAATTTAAAACTTTTATGGGAGCTATAAAATTTTATAGTAGTTATGCATTAAAAACTTT
TGATAATAAATATTATTTAGAAGATTTTGAAGATCGTGCATGCATGGTTGCATTAACGTTGGGAGGTGGAAATGAAAAAT
TTGCTATAAACATTATGCAAGAAATATTATCTGGAAGATTTCAACCAGCTACTCCAACTTTTTTAAATTGTGGCAAAAAA
CAACGTGGAGAATATGTATCATGTTTTTTACTAAGAATAGAAGATAATATGGAATCTATTGGTCGGGCATTAAACTCTGC
TTTACAACTTTCAAAAAGAGGTGGAGGTGTATCTTTTTTGTTAACAAATTTAAGAGAATCAGGAGCTCCAATAAAATGTA
TAAAAAATCAATCCTCTGGAATTGTTCCAGTGATGAAAATGCTAGAAGATGCTTTTTCTTATGCTAATCAATTAGGAGCT
AGACAAGGAGCTGGAGCAGTATACTTACATGCTCATCATCCTGATATACTAAATTTTTTAGACACTAAAAGAGAAAATGC
AGATGAAAAAATTAGAATAAAAACGTTGTCATTAGGTGTAATTATACCTGACATTACATTTAAATTAGCAAAAGAAAATC
AAAATATGTGTCTATTTTCTCCATATGATATAAAAAAAGTATACAATAAACCATTTTCAGAATTAATAATTAGTAAAATA
TACTATAAATTAATTAATGATATAAGAATTAAAAAAATTTCAATAAATGCTCGTAGTTTTTTTCAAAAATTAGCTGAAGT
TCAATTTGAATCTGGATATCCATATATTATGTTTGAAGATACTGTTAATAAAGAAAACCCTATTTATGGAAAAATAAATA
TGAGCAACTTATGTTCAGAAATACTTCAAGTTAATACGGCTTCAGAATATAATGAAGATTTAAGTTACAAAAAAATAGGA
AGAGATATTTCTTGTAACTTAGGATCTTTAAATATAGCTAAAACTATGGATTCTTCAAATTTAGGAAAAACTGTAGAAGT
TGCTATTAGATGTTTAACAGCCGTTTCTGATATTACAAAAATAAATTCTGTATCTTCTGTTGTTAAAGGTAATAAAAAAT
CTCATTCAATTGGATTGGGTCAAATGAATTTACATGGATATTTAGCTAGAGAAAATATTTTTTATGGAAGTCCAGAAGCT
ATAGAATTCACAAATTTTTATTTTTATGTTATAACTTATCATGCTATTAGAACATCTAATTTGTTAGCAATTGAAAGAAA
AAAAACGTTCAGTGGATTTTCTAGATCTAAATATGCCAATGGGAAATTTTTTAAAAAATACACAAAAAAAACATGGATCC
CTAAAAGCGATAGAATACTTAATTTATTTAACAACAATAATATCCATTTGCCTACTCTAAAAGAGTGGAAAATTTTAGAA
AATAGCGTTATGAAATATGGATTATATAATCAAAATTTGCAAGCAATTCCTCCAACAGGTTCAATTTCTTATATTAATTA
TTCAACTTCAAGCATACATCCAGTCGTGTCAAGAATAGAAATAAGAAAAGAAGGTAAAATTGGTAGAGTATATTATCCTG
CTCCGTATATGACAAACAAAAATTTGTGTTACTATCAAGACGCCTACGAAATAGGTCCAAAAAAAATTATAGACACATAT
GCTGCTGCTACTAAACATGTAGATCAAGGTCTTTCTTTAACATTATTTTTTAGAGATGATGCTACTACAAGAGATATAAA
TAAAGCACAAATATATGCATGGAAAAAAGGAATTAAAACATTATATTATGTTAGAATTCGTCAATTAACACTAAAAGGAA
CTGAATTATTTGGATGTGTATCTTGTTCATTATAA

Protein sequence :
MHKIDYHALNAMLNLYDKNGLLQIEKDVFAINSYYEQHVLPNKKKFSSLEDRITYLLKEEYYESNVFENYKKDFIKNIFF
QSKKQGFKFKTFMGAIKFYSSYALKTFDNKYYLEDFEDRACMVALTLGGGNEKFAINIMQEILSGRFQPATPTFLNCGKK
QRGEYVSCFLLRIEDNMESIGRALNSALQLSKRGGGVSFLLTNLRESGAPIKCIKNQSSGIVPVMKMLEDAFSYANQLGA
RQGAGAVYLHAHHPDILNFLDTKRENADEKIRIKTLSLGVIIPDITFKLAKENQNMCLFSPYDIKKVYNKPFSELIISKI
YYKLINDIRIKKISINARSFFQKLAEVQFESGYPYIMFEDTVNKENPIYGKINMSNLCSEILQVNTASEYNEDLSYKKIG
RDISCNLGSLNIAKTMDSSNLGKTVEVAIRCLTAVSDITKINSVSSVVKGNKKSHSIGLGQMNLHGYLARENIFYGSPEA
IEFTNFYFYVITYHAIRTSNLLAIERKKTFSGFSRSKYANGKFFKKYTKKTWIPKSDRILNLFNNNNIHLPTLKEWKILE
NSVMKYGLYNQNLQAIPPTGSISYINYSTSSIHPVVSRIEIRKEGKIGRVYYPAPYMTNKNLCYYQDAYEIGPKKIIDTY
AAATKHVDQGLSLTLFFRDDATTRDINKAQIYAWKKGIKTLYYVRIRQLTLKGTELFGCVSCSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 66