Gene Information

Name : nrdF (WGLp609)
Accession : NP_871612.1
Strain : Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Genome accession: NC_004344
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 693847 - 694821 bp
Length : 975 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAAAACAAATTAGAAAAATCAAATAATATATACGCTATTAATTGGAATAGAATAGAAGACGAAAAAGATCTAGAAGT
TTGGAATCATGTAACAACAAATTTTTGGCTTCCAGAAAAAATACCACTATCTAATGATATCCAATCTTGGAAAATGTTAT
CTAAAGAAGAAAAAAAATTAACAATAAGAATTTTTACAGGGTTAACCTTGCTTGATACTTTGCAAAATATTATCGGGGCT
CCATCCATTATGATGGATGCTAAAACAATGCACGAAAAAGCAGTAATTTCTAACATTGGATTTATGGAAGCAGTACATGC
AAGGTCATATAGCTCTATATTTTCTACATTATGTTCAACTACAGAAGTAGATTCAGCATATTTTTGGAGCGAAAAAAATA
AATTTCTTCAAAATAAAGTAAATATCATTTCAAAAATTTATTTAGAAAAAAATTCTTTAAAAAAGAAAATTGCAAGTGTT
TTTTTAGAATCATTTTTATTTTATTCTGGATTTTATTTACCAATGTTTTACTCTAGTAGAGGTAAATTGACAAATACTTC
TGATTTAATAAGATTAATAATTAGAGATGAAGCTGTTCATGGTTATTATATAGGTTATAAATTTCAAAAAGATCTTATTT
CATTAAATGAAAAAGAAAAAAAGAACATTAAAGATTTTGCTTTTAATTTATTATATAAATTGTATGAAAATGAAATAAAT
TACAGTTATTCTTTATACAAAGATATTATTCCAATAAAAAACATAATTTCTTTTTTAAATTATAACGCTAATAAATCTTT
AATGAATCTTGGATACGAGCAATATTTTCCAGATGATGAATCATTGGTAAATCCGGATATTTTATCAGCTTTAACTCCTA
ATTCAAATGAAAATCATGATTTTTTTTCTGGATCTGGATCTTCTTACGTGATGGGAAAAACTGTTTTGACAAAAGATGAA
GATTGGACTTTTTAA

Protein sequence :
MKNKLEKSNNIYAINWNRIEDEKDLEVWNHVTTNFWLPEKIPLSNDIQSWKMLSKEEKKLTIRIFTGLTLLDTLQNIIGA
PSIMMDAKTMHEKAVISNIGFMEAVHARSYSSIFSTLCSTTEVDSAYFWSEKNKFLQNKVNIISKIYLEKNSLKKKIASV
FLESFLFYSGFYLPMFYSSRGKLTNTSDLIRLIIRDEAVHGYYIGYKFQKDLISLNEKEKKNIKDFAFNLLYKLYENEIN
YSYSLYKDIIPIKNIISFLNYNANKSLMNLGYEQYFPDDESLVNPDILSALTPNSNENHDFFSGSGSSYVMGKTVLTKDE
DWTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-90 58