Gene Information

Name : thiC (WGLp507)
Accession : NP_871510.1
Strain : Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Genome accession: NC_004344
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 584133 - 585947 bp
Length : 1815 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTTCTTCAAAAAAAGAATCTAGAAATAACGCAAAAAATTTTATAAAAAATTTTTCCGAAAATTTATATCCAAATTC
TAATCGTGTTTATTTAAATAACTCTGATAAATCTATAAAAGTTCCAGTAAGATCAGTTGAATTAAATAGAACAGAAATAA
TAGATAATAATAATAAAATTAAATATGAAGAAAATTCCCCCGTCATGATATATGATACTTCTGGTCCTTACGGAGATCCA
AAATCATTAATTGATATGAAATCTGGTTTAAATAAATTAAGAAATAAATGGATTATAGATAGAAAGGATGTTGAATTAAT
TTCAAAAAATTTAAATTTAGAAAATAAAAATAATAATTTTAAAAAAAATATTGATCATTATATATCAAAAAAAAATAGAT
GTATAACTCAATTATATTATGCCAAATCTGGAATTATTACAAAAGAAATGGAATTTGTATCAATTAGAGAAAACATGAAT
TACGAATATTCAGAAAGTGAAGCAAAAAATAATAAAAAAATTACTCCAGAATTTGTAAGAAAAGAAGTAGCATCAGGCAG
GGCTATCATACCATCAAATATTAATCATCCAGAATCTGAGCCTATGGTTATAGGAAGAAATTTTTTTGTCAAGATTAATG
CAAATATTGGAAATTCTTCTATTTCTTCTTCCATAGAAGAGGAGGTTCAAAAATTAATATGGTCTGTTAAATGGGGCGCT
GACACTGTAATGGATTTGTCAACAGGTAGAAATATACATGAAACTAGAGAATGGATATTAAGAAACAGCCCAGTTCCAAT
AGGAACAGTTCCAATTTATCAAGCTTTAGAAAAAGCTAATGGAATAGTTGAAAATTTAAATTGGAAAATTTTTAAAAAAA
CTCTATTAGAACAAGCAGAACAAGGTGTAGATTATTTTACTATACATGCTGGTTTATTATTACGTTATATACCAATGACA
TCAAATAGATTAACTGGGATAGTTTCTAGAGGAGGATCAATTATAGCGAAATGGTGTTTATTTCATCATAAAGAAAATTT
CATTTATGAAAATTTTGAAGAAATATGTAAAATTTGCTCTTGTTACGATATATCATTATCGCTAGGAGATGGTTTGAGAC
CTGGATCAATAAAGGATGCTAATGATGAAGCACAGTTTGCAGAGCTTTACACTTTAGGCAAATTAACAAAAGTAGCTTGG
AATTATAATGTTCAAGTAATGATAGAAGGCCCTGGACACGTTCCTATTAATATGATTAAAGAAAATATGACAAAACAATT
AAAATATTGTCATGAAGCTCCTTTTTACACATTAGGCCCATTAACTACAGATATAGCTCCAGGATATGATCATTTTACTT
CAGGAATTGGAGCTGCATTAATTGGATGGTATGGTTGTGCGATGTTATGCTATGTTACTCCAAAAGAACATTTAGGATTA
CCAAATAAAGAGGATGTTAAACAAGGTTTGATAGCTTATAAAATAGCTGCTCATGCCGCAGATATAGCAAAAGGTCATCA
TATATCTCAAATAAGAGATGATGCAATATCAAAAGCTAGATTTGAATTCAGATGGGAAGATCAATTTAACCTTTCTATAG
ATCCAAATACAGCTAGATCATTTCATGATGAAACATTACCAAAATCTTCTGGAAAAAATTTTCATTTTTGTTCTATGTGC
GGTCCAAAATTTTGCTCAATGAAAATTTCTCAAGAAGTTAGAGATTTTGCAAAAAACAAAAAAATAATAGATGGAATGAA
TAAAATGTCAGAAATTTTTAAAAAAAATAATAATAAAATGTCTTTAAAAAAATAA

Protein sequence :
MSSSKKESRNNAKNFIKNFSENLYPNSNRVYLNNSDKSIKVPVRSVELNRTEIIDNNNKIKYEENSPVMIYDTSGPYGDP
KSLIDMKSGLNKLRNKWIIDRKDVELISKNLNLENKNNNFKKNIDHYISKKNRCITQLYYAKSGIITKEMEFVSIRENMN
YEYSESEAKNNKKITPEFVRKEVASGRAIIPSNINHPESEPMVIGRNFFVKINANIGNSSISSSIEEEVQKLIWSVKWGA
DTVMDLSTGRNIHETREWILRNSPVPIGTVPIYQALEKANGIVENLNWKIFKKTLLEQAEQGVDYFTIHAGLLLRYIPMT
SNRLTGIVSRGGSIIAKWCLFHHKENFIYENFEEICKICSCYDISLSLGDGLRPGSIKDANDEAQFAELYTLGKLTKVAW
NYNVQVMIEGPGHVPINMIKENMTKQLKYCHEAPFYTLGPLTTDIAPGYDHFTSGIGAALIGWYGCAMLCYVTPKEHLGL
PNKEDVKQGLIAYKIAAHAADIAKGHHISQIRDDAISKARFEFRWEDQFNLSIDPNTARSFHDETLPKSSGKNFHFCSMC
GPKFCSMKISQEVRDFAKNKKIIDGMNKMSEIFKKNNNKMSLKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 3e-175 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 3e-175 63
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 3e-172 59