Gene Information

Name : serS (WGLp489)
Accession : NP_871492.1
Strain : Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Genome accession: NC_004344
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 565684 - 566973 bp
Length : 1290 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATAGATCATAAACTAATAATAAAAAATATAGAAGAAGTTTGTAAAAAATTGATTTTGAGAAATTTTTATTTAGATAA
AAAAAAAATATTGCTTCAAGATCAAAAAAGAAAAATATTACAAATAGAAGTAGAAAAATTACAAAATAAACGCAATTTAC
AATCTAAAATAATAAGTAAAATAAAAATTAATAATAAAAATATTGATATTTATAAAAATAAATCTAATAAAATTAATATT
TTATTAAATGAAAAAAAACAAAAATTAAAAAAAATAAAAAAAGAAATTGACAATTATTTATCTACAATTCCAAATATTCT
AGACGAAAAAGTTCCAATAGGAAAAGATCAAAAAAATAATATTGAAGTGAAAAAATGGGGATCTCCAAAAATATACAATT
TTAAAATAAAAAGCCACGTAGAAATAGGAGAAAAAATTAAATATCTAGATTTTTCAAGATCCGCAAAAATATCTGGTAGT
AGGTTTGTGGTTATGAAAAATAAAATATCATACATGCATCGAGCTTTGTCCCAATTTATGCTAAATTTACATACAAATCA
ACATGGATATGAAGAATATTATGTACCATATTTGGTAAATAAAAACATGCTATATGGTACTGGTCAGCTACCTAAATTTT
ATAATGATTTTTTTTATGCAAAATCATTTTTTGAGGACATACAAAGTTGTTATGCACTAATACCTACAGCAGAAGTTCCT
CTAACAAATTTAATGAGAAATGAAATTATTGATGAAAATTATTTGCCTATAAAAATGACTTCTCATACTCCTTGTTTTAG
ATCAGAAGCAGGATCCTATGGAAAAGATACTAAAGGTTTGATACGTATGCATCAGTTTGATAAAGTAGAAATTGTACAAA
TAGTATCTCCAGAAAATTCTATAAAAGCTTTAGAAGAAATCACTCATCATGCAGAACGTGTACTTCAGCTGTTAGATTTA
CCATATAGAAAAATATTATTATGTTCTGGTGATACTGGATTTTCTTCTTGTAAAACATATGATTTAGAAGTTTGGATGCC
TTCTAGAAATAAATACATAGAAGTATCTTCTTGTTCTAATACAAGTGATTTTCAATCTAGAAGAACTAAAATTCGTTATA
GAAAAATTTCAAATAAAGAAATACATTTAACTCATATATTAAATGGATCTGCTTTAGCTATAAGCAGAACTCTAGCTTCT
ATAATAGAAAATTATCAAACTAAAGAAGGTAATATTAAAGTTCCCAAAATATTACAACCTTATATGGATGGATTAAAATT
AATTAAGTAA

Protein sequence :
MIDHKLIIKNIEEVCKKLILRNFYLDKKKILLQDQKRKILQIEVEKLQNKRNLQSKIISKIKINNKNIDIYKNKSNKINI
LLNEKKQKLKKIKKEIDNYLSTIPNILDEKVPIGKDQKNNIEVKKWGSPKIYNFKIKSHVEIGEKIKYLDFSRSAKISGS
RFVVMKNKISYMHRALSQFMLNLHTNQHGYEEYYVPYLVNKNMLYGTGQLPKFYNDFFYAKSFFEDIQSCYALIPTAEVP
LTNLMRNEIIDENYLPIKMTSHTPCFRSEAGSYGKDTKGLIRMHQFDKVEIVQIVSPENSIKALEEITHHAERVLQLLDL
PYRKILLCSGDTGFSSCKTYDLEVWMPSRNKYIEVSSCSNTSDFQSRRTKIRYRKISNKEIHLTHILNGSALAISRTLAS
IIENYQTKEGNIKVPKILQPYMDGLKLIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-82 51