Gene Information

Name : ylcA (SF0472)
Accession : NP_706418.1
Strain : Shigella flexneri 301
Genome accession: NC_004337
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional activator CusR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 488664 - 489347 bp
Length : 684 bp
Strand : -
Note : Code: TK; COG: COG0745

DNA sequence : 
ATGAAACTGTTGATTGTCGAAGATGAAAAGAAAACCGGAGAATACTTGACCAAAGGGTTAACCGAAGCCGGTTTTGTGGT
CGATTTGGCCGACAACGGGCTGAATGGCTACCATCTGGCGATGACCGGTGATTATGACCTGATAATCCTCGATATTATGC
TGCCAGACGTGAACGGCTGGGATATCGTGCGCATGTTGCGCTCCGCCAATAAAGGGATGCCGATTCTGTTGCTTACCGCG
CTTGGCACCATTGAACATCGCGTCAAGGGGCTGGAGTTGGGGGCAGATGACTACCTGGTGAAACCGTTCGCTTTTGCTGA
ACTGCTGGCGCGGGTGCGCACTCTCCTGCGGCGCGGGGCGGCGGTGATTATCGAAAGTCAGTTTCAGGTTGCCGATCTGA
TGGTCGATCTCGTCAGCCGCAAAGTCACCCGCAGCGGCACGCGCATCACTCTGACCAGTAAAGAATTTACTCTGCTGGAG
TTTTTTCTCCGCCATCAGGGCGAAGTGCTGCCCCGCTCGCTTATCGCCTCGCAGGTATGGGACATGAATTTCGACAGCGA
CACTAACGCCATTGATGTGGCGGTGAAGCTGCTACGCGGCAAAATCGACAACGACTTTGAGCCGAAGCTGATTCAAACCG
TGCGCGGCGTGGGTTACATGCTTGAGGTGCCGGATGGTCAGTAA

Protein sequence : 
MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTA
LGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKLLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 3e-55 52
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 4e-55 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ylcA NP_706418.1 DNA-binding transcriptional activator CusR BAC0111 Protein 7e-103 99
ylcA NP_706418.1 DNA-binding transcriptional activator CusR BAC0347 Protein 3e-86 82
ylcA NP_706418.1 DNA-binding transcriptional activator CusR BAC0083 Protein 1e-69 61
ylcA NP_706418.1 DNA-binding transcriptional activator CusR BAC0638 Protein 2e-62 61
ylcA NP_706418.1 DNA-binding transcriptional activator CusR BAC0308 Protein 8e-63 60
ylcA NP_706418.1 DNA-binding transcriptional activator CusR BAC0197 Protein 7e-63 59
ylcA NP_706418.1 DNA-binding transcriptional activator CusR BAC0125 Protein 6e-63 56
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_010079.5776364.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_002952.2859858.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_007622.3794948.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_003923.1003417.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_013450.8614146.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_002951.3238224.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_007793.3914065.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR NC_002758.1121390.p0 Protein 9e-35 41
ylcA NP_706418.1 DNA-binding transcriptional activator CusR AE000516.2.gene3505. Protein 3e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ylcA NP_706418.1 DNA-binding transcriptional activator CusR VFG0596 Protein 1e-55 52
ylcA NP_706418.1 DNA-binding transcriptional activator CusR VFG1390 Protein 8e-44 43
ylcA NP_706418.1 DNA-binding transcriptional activator CusR VFG1389 Protein 2e-34 41