Gene Information

Name : arsB (SF3535)
Accession : NP_709284.2
Strain : Shigella flexneri 301
Genome accession: NC_004337
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 3625400 - 3626689 bp
Length : 1290 bp
Strand : +
Note : Code: P; COG: COG1055

DNA sequence :
ATGTTACTGGCAGGCGCTATCTTTGTCCTGACCATCGTATTGGTTATCTGGCAGCCGAAAGGTTTAGGCATCGGCTGGAG
TGCAACGCTCGGCGCGGTACTGGCGTTGGTTACGGGCGTGGTTCATCCGGGTGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCGGCGTTTATTGCCGTCATTATCATCAGCCTGCTGCTGGATGAGTCCGGCTTTTTTGAATGGGCAGCG
CTGCACGTTTCACGCTGGGGCAATGGACGCGGTCGCTTGCTGTTTACCTGGATTGTCCTGCTCGGTGCCGCCGTTGCGGC
CCTGTTTGCCAATGATGGCGCGGCGCTTATTTTGACGCCGATTGTCATCGCCATGCTGCTGGCTTTAGGATTCAGTAAAG
GCACGACGCTGGCGTTCGTGATGGCGGCCGGATTCATTGCCGATACCGCCAGCCTGCCGCTTATTGTCTCCAACCTGGTG
AATATCGTTTCCGCTGATTTCTTTGGCCTCGGCTTTCGCGAATACGCCTCGGTGATGGTGCCGGTGGATATCGCCGCGAT
TGTTGCCACGCTGGTGATGCTACATCTCTATTTTCGCAAAGATATTCCGCAGAACTACGATATGGCGCTGCTGAAATCTC
CCGCAGAAGCGATCAAAGATCCTGCTACGTTCAAAACTGGCTGGGTTGTTTTACTGCTTCTGCTGGTGGGATTTTTCGTC
CTGGAACCGCTCGGCATTCCGGTGAGCGCCATTGCAGCTGTGGGCGCACTGATATTATTTGTCGTCGCTAAACGCGGTCA
TGCGATTAATACGGGTAAAGTCCTGCGCGGTGCCCCCTGGCAGATTGTCATCTTCTCGCTCGGCATGTATCTGGTGGTTT
ATGGCCTGCGCAATGCCGGATTAACGGAATATCTTTCTGGCGTACTCAACGTGCTGGCGGATAACGGCCTGTGGGCCGCG
ACGCTCGGCACCGGATTCCTCACCGCCTTCCTCTCTTCTATTATGAACAATATGCCGACGGTACTGGTTGGCGCGTTGTC
CATTGATGGCAGCACGGCATCTGGCGTTATCAAAGAAGCGATGGTTTATGCCAACGTGATTGGCTGCGATTTGGGGCCGA
AAATTACCCCGATTGGTAGCCTGGCAACGCTGCTCTGGCTGCACGTACTTTCGCAGAAGAATATGACTATCAGCTGGGGA
TATTACTTCCGTACAGGGATTATCATGACCCTGCCTGTGCTGTTTGTGACGCTGGCTGCGCTGGCGCTACGTCTCTCTTT
CACTTTGTAA

Protein sequence :
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV
LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG
YYFRTGIIMTLPVLFVTLAALALRLSFTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 7e-157 92
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 4e-95 59
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-95 59
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 4e-99 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB NP_709284.2 arsenical pump membrane protein BAC0578 Protein 3e-161 94
arsB NP_709284.2 arsenical pump membrane protein BAC0576 Protein 2e-160 94
arsB NP_709284.2 arsenical pump membrane protein BAC0031 Protein 2e-156 91
arsB NP_709284.2 arsenical pump membrane protein BAC0577 Protein 5e-155 90
arsB NP_709284.2 arsenical pump membrane protein BAC0574 Protein 9e-97 60
arsB NP_709284.2 arsenical pump membrane protein BAC0575 Protein 4e-100 60