Name : pic (SF2973) Accession : NP_708747.3 Strain : Shigella flexneri 301 Genome accession: NC_004337 Putative virulence/resistance : Virulence Product : serine protease Function : - COG functional category : - COG ID : - EC number : - Position : 3067737 - 3071855 bp Length : 4119 bp Strand : - Note : - DNA sequence : GTGAATAAAGTTTATTCTCTTAAATATTGCCCCGTCACCGGGGGGCTTATTGCTGTCTCTGAACTTGCCCGCAGGGTAAT AAAAAAGACATGCCGAAGATTAACGCATATTCTTCTGGCTGGCATTCCAGCAATCTGTCTGTGTTACTCTCAGATATCCC AGGCGGGTATTGTCCGTTCCGATATTGCCTATCAGATTTATCGTGATTTCGCCGAAAACAAAGGGCTTTTTGTACCTGGT GCCAATGATATTCCGGTATATGATAAGGACGGAAAACTTGTGGGAAGACTGGGTAAAGCCCCAATGGCCGATTTCAGCAG TGTGAGCTCAAATGGCGTTGCTACGCTTGTATCGCCTCAGTATATCGTCAGCGTAAAGCATAACGGAGGATATCGGAGTG TGAGCTTTGGTAATGGGAAAAATACATATTCCCTTGTTGACCGTAATAACCACCCTTCTATTGACTTCCATGCTCCACGT CTGAATAAACTGGTTACAGAAGTTATTCCCTCAGCGGTAACATCAGAAGGAACCAAAGCCAATGCTTATAAATACACTGA ACGTTACACCGCTTTTTATCGGGTGGGTAGTGGTACGCAGTACACTAAGGACAAGGACGGAAATTTAGTTAAGGTTGCCG GTGGATATGCTTTTAAAACAGGAGGAACCACAGGAGTTCCTCTGATATCTGATGCAACAATAGTCTCTAATCCCGGGCAA ACTTATAATCCTGTAAACGGCCCTTTACCTGACTATGGAGCCCCTGGGGATAGTGGTTCTCCTTTGTTTGCTTATGATAA ACAACAAAAAAAATGGGTTATTGTTGCTGTATTAAGAGCATATGCAGGTATTAATGGTGCTACGAACTGGTGGAATGTCA TACCAACAGATTATCTGAACCAGGTTATGCAGGACGATTTCGATGCCCCCGTAGACTTTGTTTCCGGACTGGGCCCCCTG AACTGGACATACGACAAAACATCAGGCACAGGTACCCTGAGCCAGGGCAGTAAAAACTGGACCATGCACGGGCAGAAAGA CAATGACCTCAATGCCGGTAAAAATCTGGTATTCAGCGGGCAGAATGGTGCAATTATCCTGAAAGACAGTGTGACTCAGG GTGCCGGTTATCTCGAATTTAAAGACAGTTACACCGTATCTGCTGAATCCGGAAAAACATGGACGGGTGCCGGCATTATT ACTGACAAGGGGACGAATGTAACCTGGAAGGTCAACGGCGTTGCCGGTGACAACTTGCATAAGCTGGGGGAAGGAACCCT GACCATAAACGGAACAGGTGTAAACCCGGGAGGACTGAAAACGGGAGACGGTATCGTTGTACTTAACCAGCAGGCAGACA CTGCAGGTAATATCCAGGCCTTCAGTTCAGTGAACCTCGCCAGCGGACGTCCGACCGTGGTGCTCGGGGATGCCCGTCAG GTCAATCCGGATAACATTTCATGGGGATACCGGGGAGGTAAGCTTGACCTTAATGGTAATGCCGTTACCTTCACCCGACT GCAGGCTGCTGATTACGGGGCGGTGATTACAAATAATGCACAGCAAAAATCCCAGCTTTTACTGGATCTTAAGGCTCAGG ATACAAATGTCAGTGAACCGACGATTGGAAATATATCCCCCTTTGGTGGTACCGGCACTCCAGGAAACCTGTACAGCATG ATACTCAACAGCCAGACCCGCTTCTATATTCTGAAATCTGCCAGCTATGGTAACACTCTGTGGGGGAACAGCCTGAATGA TCCGGCTCAGTGGGAGTTTGTTGGCATGAACAAAAACAAAGCAGTTCAGACAGTAAAAGATAGGATCCTGGCCGGGCGGG CAAAACAACCCGTTATCTTTCATGGTCAGCTGACCGGGAATATGGATGTCGCCATTCCACAGGTGCCGGGGGGAAGAAAG GTAATCTTTGATGGTAGCGTGAACCTGCCGGAAGGTACCCTGAGTCAGGACAGTGGCACCCTGATATTCCAGGGACATCC GGTTATCCATGCCTCCATCAGTGGCAGTGCACCGGTCAGCCTGAACCAGAAAGACTGGGAAAACCGTCAGTTTACAATGA AAACACTGTCGCTGAAAGACGCTGACTTCCATCTTTCACGTAACGCCTCGCTGAACAGTGACATTAAGTCGGATAACAGC CATATCACACTGGGAAGTGACAGGGCATTTGTGGATAAAAATGACGGAACAGGAAATTATGTCATTCCGGAGGAAGGTAC CTCTGTCCCGGACACCGTGAATGACAGGAGCCAGTATGAAGGGAATATTACGCTGAACCATAACTCAGCCCTGGATATCG GCAGCAGGTTCACCGGGGGGATTGACGCTTATGACAGTGCCGTCAGCATCACCTCTCCGGACGTCCTGTTGACAGCCCCG GGTGCTTTTGCCGGCAGTTCACTGACAGTGCATGATGGCGGTCATCTTACAGCACTGAACGGTCTTTTCAGCGACGGGCA TATTCAGGCCGGTAAGAACGGCAAAATCACCCTGAGCGGTACACCGGTTAAAGATACGGCTAATCAGTATGCCCCTGCTG TATATCTGACGGACGGATATGACCTGACCGGCGATAACGCAGCACTGGAAATTACCCGTGGAGCACATGCTTCCGGTGAT ATTCATGCCTCTGCGGCATCAACAGTTACCATCGGGTCTGACACGCCGGCAGAACTGGCTTCTGCGGAAACGGCTGCATC GGCGTTTGCCGGCAGTCTTCTTGAGGGCTATAACGCAGCATTCAATGGTGCCATAACCGGTGGCAGGGCTGATGTCAGTA TGCATAATGCACTGTGGACTCTGGGTGGGGACTCTGCCATCCACAGTCTTACCGTCAGAAACAGCCGTATTAGTTCTGAA GGAGACCGTACATTCCGTACCCTGACGGTGAATAAACTGGATGCAACAGGCAGTGATTTTGTTTTGCGTACGGACCTGAA AAATGCCGATAAAATTAATGTGACTGAAAAAGCCACTGGTTCAGATAACAGCCTGAACGTCAGCTTTATGAATAATCCTG CTCAGGGACAGGCCCTGAATATTCCTCTGGTCACGGCACCGGCGGGAACTTCAGCAGAGATGTTTAAGGCCGGCACCCGG GTGACAGGTTTCAGTCGGGTGACCCCAACCCTGCATGTTGATACCAGTGGTGGCAATACGAAGTGGATACTGGATGGTTT TAAAGCGGAGGCTGATAAAGCCGCTGCCGCGAAGGCTGACAGTTTCATGAATGCCGGGTATAAAAACTTCATGACGGAAG TTAACAATCTGAACAAACGTATGGGTGACCTGCGTGACACAAACGGTGATGCCGGTGCCTGGGCGCGCATCATGAGTGGT GCCGGTTCTGCAGACGGTGGTTACAGTGATAATTACACCCATGTTCAGGTCGGCTTTGACAAAAAACATGAACTGGACGG TGTGGACCTGTTTACCGGTGTCACGATGACCTATACCGACAGCAGTGCAGACAGCCATGCATTCAGCGGAAAGACGAAAT CGGTGGGGGGCGGTCTGTATGCTTCAGCATTGTTTGAGTCCGGTGCCTATATCGATTTGATTGGTAAATATATTCACCAT GACAATGATTACACAGGTAACTTTGCTAGCCTGGGAACGAAACACTACAACACCCATTCCTGGTATGCCGGTGCTGAAAC GGGTTACCGCTATCACCTGACAGAGGACACGTTCATTGAGCCGCAGGCTGAACTGGTTTACGGCGCCGTGTCCGGGAAAA CATTCCGCTGGAAAGACGGTGATATGGACCTGAGCATGAAGAACAGGGACTTCAGTCCGCTGGTTGGAAGAACAGGGGTT GAACTGGGCAAGACCTTCAGTGGTAAGGACTGGAGTGTGACGGCCCGTGCCGGAACCAGCTGGCAGTTTGACCTGCTGAA TAATGGAGAGACCGTACTGCGTGATGCGTCCGGGGAGAAACGGATAAAAGGAGAGAAGGACAGCCGGATGCTGTTTAATG TTGGTATGAATGCGCAGATAAAGGACAATATGCGCTTTGGTCTGGAGTTTGAGAAGTCAGCCTTTGGTAAATATAACGTG GATAATGCGGTAAACGCGAATTTCCGGTATATGTTCTGA Protein sequence : MNKVYSLKYCPVTGGLIAVSELARRVIKKTCRRLTHILLAGIPAICLCYSQISQAGIVRSDIAYQIYRDFAENKGLFVPG ANDIPVYDKDGKLVGRLGKAPMADFSSVSSNGVATLVSPQYIVSVKHNGGYRSVSFGNGKNTYSLVDRNNHPSIDFHAPR LNKLVTEVIPSAVTSEGTKANAYKYTERYTAFYRVGSGTQYTKDKDGNLVKVAGGYAFKTGGTTGVPLISDATIVSNPGQ TYNPVNGPLPDYGAPGDSGSPLFAYDKQQKKWVIVAVLRAYAGINGATNWWNVIPTDYLNQVMQDDFDAPVDFVSGLGPL NWTYDKTSGTGTLSQGSKNWTMHGQKDNDLNAGKNLVFSGQNGAIILKDSVTQGAGYLEFKDSYTVSAESGKTWTGAGII TDKGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGIVVLNQQADTAGNIQAFSSVNLASGRPTVVLGDARQ VNPDNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITNNAQQKSQLLLDLKAQDTNVSEPTIGNISPFGGTGTPGNLYSM ILNSQTRFYILKSASYGNTLWGNSLNDPAQWEFVGMNKNKAVQTVKDRILAGRAKQPVIFHGQLTGNMDVAIPQVPGGRK VIFDGSVNLPEGTLSQDSGTLIFQGHPVIHASISGSAPVSLNQKDWENRQFTMKTLSLKDADFHLSRNASLNSDIKSDNS HITLGSDRAFVDKNDGTGNYVIPEEGTSVPDTVNDRSQYEGNITLNHNSALDIGSRFTGGIDAYDSAVSITSPDVLLTAP GAFAGSSLTVHDGGHLTALNGLFSDGHIQAGKNGKITLSGTPVKDTANQYAPAVYLTDGYDLTGDNAALEITRGAHASGD IHASAASTVTIGSDTPAELASAETAASAFAGSLLEGYNAAFNGAITGGRADVSMHNALWTLGGDSAIHSLTVRNSRISSE GDRTFRTLTVNKLDATGSDFVLRTDLKNADKINVTEKATGSDNSLNVSFMNNPAQGQALNIPLVTAPAGTSAEMFKAGTR VTGFSRVTPTLHVDTSGGNTKWILDGFKAEADKAAAAKADSFMNAGYKNFMTEVNNLNKRMGDLRDTNGDAGAWARIMSG AGSADGGYSDNYTHVQVGFDKKHELDGVDLFTGVTMTYTDSSADSHAFSGKTKSVGGGLYASALFESGAYIDLIGKYIHH DNDYTGNFASLGTKHYNTHSWYAGAETGYRYHLTEDTFIEPQAELVYGAVSGKTFRWKDGDMDLSMKNRDFSPLVGRTGV ELGKTFSGKDWSVTARAGTSWQFDLLNNGETVLRDASGEKRIKGEKDSRMLFNVGMNAQIKDNMRFGLEFEKSAFGKYNV DNAVNANFRYMF |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
pic | NP_838464.1 | serine protease precurser | Virulence | SHI-1 | Protein | 0.0 | 100 |
pic | NP_708747.3 | serine protease | Not tested | SHI-1 | Protein | 0.0 | 100 |
she | AAB58244.1 | mucinase | Virulence | SHI-1 | Protein | 0.0 | 99 |
pic | AAK00464.1 | Pic | Virulence | SHI-1 | Protein | 0.0 | 99 |
unnamed | CAC39286.1 | hypothetical protein | Not tested | LPA | Protein | 0.0 | 53 |
vat | AAO21903.1 | vacuolating autotransporter toxin | Virulence | Not named | Protein | 0.0 | 48 |
unnamed | CAD66214.1 | putative hemoglobin protease | Not tested | PAI III 536 | Protein | 0.0 | 47 |
vat | YP_851472.1 | vacuolating autotransporter | Not tested | PAI III APEC-O1 | Protein | 0.0 | 47 |
Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
pic | NP_708747.3 | serine protease | VFG0635 | Protein | 0.0 | 100 |
pic | NP_708747.3 | serine protease | VFG0861 | Protein | 0.0 | 99 |
pic | NP_708747.3 | serine protease | VFG0903 | Protein | 0.0 | 97 |
pic | NP_708747.3 | serine protease | VFG1689 | Protein | 0.0 | 47 |
pic | NP_708747.3 | serine protease | VFG0904 | Protein | 0.0 | 47 |