Gene Information

Name : serS (BR0885)
Accession : NP_697898.1
Strain :
Genome accession: NC_004310
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 857683 - 858966 bp
Length : 1284 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGACATCAAATGGATTCGCGAAAACCCGGAAACCCTCGACAAGGCGCTCGCAAAGCGTGGGGCTGCTCCGCTTTC
GTCCGAACTGATTGCGCTGGATGAAAAGCGCCGCGAGCATGTCGGCAAGGTGCAGGCAGCGCAGGAGCGCCGCAATGCCG
CCTCGAAGGAAATCGGCAAGGCCATGGCCGCAAAGGACATGGGCACGGCTGAAAAGCTGAAGGCCGAAGTGGGCGAACTG
AAAGATTTTCTCGCCCATGCGGAAGAAGACGAGCGCCGCCTCAGCAAGGAACTGAGCGACGCATTGTCCACCATTCCCAA
TATTCCGCTTGATGATGTGCCGCTCGGCAAGGATGAAAGCGACAATGTTGAGCTGCGCCGCATTGGCAACCCGCACAATT
TCTCCTTCCAGCCGAAAGAGCATTTTGAGCTTGGCGAGGCGCTTGGATACATGGATTTCGAGCGCGCGGCCAAGCTTGCC
GGTGCGCGCTTTACGGTGCTGAAAGGCCCGCTCGCCCGTCTTGAGCGCGCGCTTGGCCAGTTCATGCTCGATCTTCACAC
GACAGAACACGGTTATACCGAAGTCATGCCGCCGCTGATGGTGCGCGACGAAGCGGTCTATGGCACGGGGCAATTGCCGA
AGTTTTCAGAAGATCTTTTCCGCACGACGGATGGCCGCTGGCTGATCCCGACGGCGGAGGTGCCGCTCACCAATCTGGTT
GCCGAAGAAATTGTCGATATGAAGGGGCTGCCGCTGCGCTTCACGGCGCTGACCCCATGTTTTCGCTCGGAAGCGGGGTC
GGCCGGGCGCGATACGCGCGGCATGTTGCGCCAGCATCAGTTCCTGAAAGTGGAGATGGTATCGATCACCGATGCGGAAA
GCTCCGTTGCCGAGCATGAGCGCATGACGGCTTGCGCGGAAGAAGTGCTGAAGCGGCTGGGCCTGCCGTTCCGTACCGTT
GTGCTTTGCACGGGCGACATGGGCTTTGGCGCACAGCGGACCTATGATATCGAGGTCTGGTTGCCGGGGCAGAACACCTA
TCGCGAAATTTCAAGCTGTTCGACCTGCGGTGATTTCCAGGGCCGCCGCATGAATGCCCGCTATCGCCCGGAAGGCGAGA
AATCCACGCGCTTCGTGCACACCCTCAACGGGTCGGGCGTTGCTGTCGGGCGCGCGCTGATTGCGGTTATGGAAAATTAC
CAGCAGGAAGACGGCAGCATTCATATTCCTGAAGCATTACAGCCATATATAGGCGGCCTCACGCGGATCGAAAAAGCCGC
TTGA

Protein sequence :
MLDIKWIRENPETLDKALAKRGAAPLSSELIALDEKRREHVGKVQAAQERRNAASKEIGKAMAAKDMGTAEKLKAEVGEL
KDFLAHAEEDERRLSKELSDALSTIPNIPLDDVPLGKDESDNVELRRIGNPHNFSFQPKEHFELGEALGYMDFERAAKLA
GARFTVLKGPLARLERALGQFMLDLHTTEHGYTEVMPPLMVRDEAVYGTGQLPKFSEDLFRTTDGRWLIPTAEVPLTNLV
AEEIVDMKGLPLRFTALTPCFRSEAGSAGRDTRGMLRQHQFLKVEMVSITDAESSVAEHERMTACAEEVLKRLGLPFRTV
VLCTGDMGFGAQRTYDIEVWLPGQNTYREISSCSTCGDFQGRRMNARYRPEGEKSTRFVHTLNGSGVAVGRALIAVMENY
QQEDGSIHIPEALQPYIGGLTRIEKAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-102 54