Gene Information

Name : smpB (BL1180)
Accession : NP_696349.1
Strain : Bifidobacterium longum NCC2705
Genome accession: NC_004307
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1036142 - 1036741 bp
Length : 600 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
TTGAAGAGGAACCCTTTTCGTATTCGAGGCCGGTCCGTGATATCGTCGGATGTTGCGTTGCTACCCACGAGTTGCTACCC
ACGAGTTGCTACTCACGAGTTATTGCCCACGAAAGGAGGAGACATGCCCAAGGAAACCGGTGAGAAACTCATCGTCCAGA
ACAAGAAGGCCCGGCATGACTATGCCATCGAAGACAAGTACGAGGCAGGGCTGGCCCTGACCGGCACCGAGGTCAAGTCG
TTGCGCGAAGGCCGCGCATCGCTGTCCGAGGCGTTCATCTCCATCGACCGCCGTGGCGAGATGTGGCTGGAGGGCGCGAA
CATCCCCGAATACCTGAACGGCACATGGAACAACCATGCGCCCAAGCGCAAGCGCAAGCTGCTGCTGCACCGATTGCAGA
TCACCAAGCTCGCCCGCGGCATCGAGGCCAAGGGATACACGATTGTGCCGCTGAGCCTGTACTTCAAGGACGGTCGCGTC
AAGGCGGAGATCGCACTGGCCCGAGGCAAGAAGGAATTCGACAAACGCCAGGCCCTGCGCGAAGAGCAGGACAAGCGTGA
AGCCCTACGCGCCATGCGCTACGCCAACATGCGCCACTAG

Protein sequence :
MKRNPFRIRGRSVISSDVALLPTSCYPRVATHELLPTKGGDMPKETGEKLIVQNKKARHDYAIEDKYEAGLALTGTEVKS
LREGRASLSEAFISIDRRGEMWLEGANIPEYLNGTWNNHAPKRKRKLLLHRLQITKLARGIEAKGYTIVPLSLYFKDGRV
KAEIALARGKKEFDKRQALREEQDKREALRAMRYANMRH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 5e-29 52
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-26 49
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-14 42