Gene Information

Name : metB (BL1155)
Accession : NP_696324.1
Strain : Bifidobacterium longum NCC2705
Genome accession: NC_004307
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1005219 - 1006403 bp
Length : 1185 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGTCCGCTGAATACAACGCCAAGTTCGCCAACACCGACATCGCCACTCGCGCCATCCACGCCGGCCAGGAGCCCGACCC
GACCACCGGTGCGGTCGTCACGCCGATCTTCGCCACCTCCACTTTCAAGCAGGATGGCGTGTTGGGCCTCAGGGGAGGCC
ACGACTACTCCCGCTCCATCAACCCCACTCGCACCAGCTTCGACGAGCAGCTCGCCGCCGTGGAAGGCGGCAAGTACGCG
CTGAGCTTCTCCTCGGGCTTGGCCGCCATCGACGTGCTGCTGCGCTCCACCATCAAGCCCGGCGACAACATCCTGCTCGG
CAACGATGTGTACGGCGGCACCTACCGCCTGCTCTCCAAGGTGTTCGTGCCGTGGGGTGTGGGCCTCGACGTGGTGAACA
TCACCGATCTGAAAGCCGTGGAAACCGCATTGGCCTCCAAGCACTACCAGTATGTGTGGGTCGAGACCCCGTCCAACCCG
CTGCTCAACATCACCGACATCGCGGCCACCACCGAAGTCGCCCACAAGTACGGCACCAAGGTCGCTGTCGACAACACCTT
CGCCTCGCCCGCCCTTCAGCACCCGCTGGCCGATGGCGCCGATGTGGTGGTCTACTCCACCACCAAGTACATCGGCGGCC
ACTCCGACGTGGTCGGCGGTGCCGTGGTGGTCAACGATGAGGAGACCCGCGAGAAGGTCGCCTTCCTGCAGAACGCCGCC
GGCGCAGTGCCCTCCCCGTTCGACTCCTGGCTGGACATCCGCGGCCTGAAGACCCTGGATCTGCGCGTCAAGCGCCACAG
TGCCAACGCCCTGAAGGTGGCCGAATGGCTCGAATCCCAGCCCTCTGATGTGATTGAGCGCGTCTGGTACCCGGGCCTCG
AGTCCCACCCGGGTCATGAAATCGCCGCCCGCCAGATGCACGGCGGCTTCGGCGGCATCGTCTCCGTGCAGCTCGCGGCC
GGCGCCGAGGCGGCCAAGCACTTCGTGGACCACACGCAGATCTTCACACTGGCCGAATCGCTCGGCGGTGTGGAAAGCCT
CATCGAGGTGCCCGCCGCCATGACCCACGCCTCCGTGGCCGGCACCACCCTGCAGGTGCCCGCCAACCTGGTGCGCATTT
CGGTCGGTATCGAGAACGCCGACGACCTTATCGCCGATCTCAAGCAGGCGTTGGATCGTATCTGA

Protein sequence :
MSAEYNAKFANTDIATRAIHAGQEPDPTTGAVVTPIFATSTFKQDGVLGLRGGHDYSRSINPTRTSFDEQLAAVEGGKYA
LSFSSGLAAIDVLLRSTIKPGDNILLGNDVYGGTYRLLSKVFVPWGVGLDVVNITDLKAVETALASKHYQYVWVETPSNP
LLNITDIAATTEVAHKYGTKVAVDNTFASPALQHPLADGADVVVYSTTKYIGGHSDVVGGAVVVNDEETREKVAFLQNAA
GAVPSPFDSWLDIRGLKTLDLRVKRHSANALKVAEWLESQPSDVIERVWYPGLESHPGHEIAARQMHGGFGGIVSVQLAA
GAEAAKHFVDHTQIFTLAESLGGVESLIEVPAAMTHASVAGTTLQVPANLVRISVGIENADDLIADLKQALDRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-71 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-72 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB NP_696324.1 cystathionine gamma-synthase BAC0207 Protein 2e-62 42