Gene Information

Name : tkt (BL0716)
Accession : NP_695899.1
Strain : Bifidobacterium longum NCC2705
Genome accession: NC_004307
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 495731 - 497839 bp
Length : 2109 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGACCGAATTCAAGGAGACCGAGCTCGACGAGCGCGCCATCAAGATGGCGAAGGTCCTTTCGGCTGACGCGGTTGAGAA
GGCAGGCTCCGGCCACCCCGGCTCCCCCATCTCCCTGGCGCCCGTCGCCTACACGCTGTACCAGCACTTCATCAAGCACG
ATCCGAATGATCCCAACTGGGAAGGCCGAGATCGCTTCATCCTTTCCGGTGGCCACGCCTCCCTCACCCAGTACGTCCAG
CTGTACTTCTCCGGCTACGGCGTGACCCTGGACGACCTTAAGAACTTCCGTGGCGGCGCTGCCACCCGCACCCCGGGCCA
CCCGGAGTACGGCCTGACCCCGGGCATCGAAATGACCACCGGCCCTCTGGGCCAGGGCTTCGCCTCCGCCATCGGCTTTG
CCTACGGCGAGCGTTTCCAGCGCGGTCTGCTTGACCCGGAGACCCCGAAGGAAGATTCCCCGTTCTACCACAAGATCTGG
GCCATCTGCGGTGAAGGCGACATCGAGGAGGGCATCTCCGGCGAGGCCGCTTCCCTGGCCGCCAACCAGAAGCTCGGCAA
CCTGACCGTGATCTTCGACGCCAACCGCATCCAGATCGAAGGCGACACCAACCTGGTGCTGGCCGAGGACGTGCTCAAGC
GCTTCCAGGCCTACGGCTGGTACACCGACGAGTTCAGCTTCATCCAGCCCGACGGCTCCTACAAGGAGGACATCGAGGGC
TTGGCTGACGTCATCGCCAAGGCCGAGAAGGCCGCTCCGGACCAGCCGAAGCTCATCAAGGTTCACTCCCTGATCGCTTG
GCCGACCCCGGGCAAGACCAACGACCCGTCCTCCCACGGTTCCAAGCTGGGTACCGAGGCTGTTGCCGGCCTCAAGGAAG
CCCTCGGCTACGATCCGGAAGAGAACTTCCACGTTGACGAAGAGGCTCTGGCTCACGCTCGCAAGGTTGCCGAGCGCGGT
CTCGAAGCCCACAAGGAATGGGACGAGAAGTTCGACGCTTGGCGCAAGGCCAACCCGGACAAGGCTGCCCTGTACGACCG
TCTGAAGGCCGGTGAACTGCCGGAAGGCTTCGACAAGGCTCTTGACGACCTTGAGGCCACCTTCGAAGTCGGCAAGGGTG
TCGCCACTCGTGGCGCCTCCGGCTCCGTGCTCAACGCCATCGCCGCTGTCATGCCGGAACTCTGGGGCGGCTCCGCCGAC
CTCGGTGGCTCCAACAAGACCGATCTCAAGGGCGCTGCCACCTTCGCCCCGGCCGAGTGCGCCACCAAGCAGTGGCCGAA
CTGCAACGAGTTCGGTCGCCAGCTGCACTTCGGCGTGCGCGAGTTCACCATGGGCTGCATCACCAACGGCATCCTGCTGG
GCTCCCACACCCGTCCGTTCGGCGGCACCTTCTTCATGTTCTCCGACTACGAGCGTTCCGCCGTTCGTCTGGCCGCCCTC
ATGGAGATTCCGAACCTGTACATCTGGTCCCACGACTCCGTCGCCGTCGGCGAGGATGGCCCGACCCACCAGCCGGTTGA
GCACCTTGCTTCCTTCCGCGCGATTCCTCAGCTTGAGGTCATTCGCCCGGCCGACGCCTTCGAGACCGCCGAGGCTTACC
GTTACTTCTTCGAGAAGAAGAACACCCTGCCTGGTGCCATGGTTCTGACCCGTCAGGGTGTCCCGGTTCTTGCCGAGACC
GCCGCCAAGGCCAAGGACGGTGTCAAGAAGGGCGCTTACGTTCTGGTCGACACCGAGGGCACTCCGGACGTCATCCTCAT
GGCTTCCGGTTCCGAGGTCCAGTGGGCTGTGGCTGCCGCCAAGACCCTGGCCGGCGAGGGCGTCAAGGCTCGCGTCGTGT
CCGTGCCGTCCATGGAATGGTTCGAGGAGCAGGACGCCGAGTACAAGGAGGCCGTGCTTCCGGCCGCTGTCAAGGCTCGT
GTCTCCGTCGAGGCCGGCGTTGCCATGCCGTGGTACAAGTACCTCGGCTCCTACGGCAAGCCCGTCTCCATCGAGCAGTT
CGGCCTGCAGGGCGACGGCGCTCAGAACATGATCGACCTCGGCATCACCGCCGAGCACGTGGTGGAAGCCGCCAAGGCCT
CCATCGCCGAAGTCGAAGCCGCCAAGTGA

Protein sequence :
MTEFKETELDERAIKMAKVLSADAVEKAGSGHPGSPISLAPVAYTLYQHFIKHDPNDPNWEGRDRFILSGGHASLTQYVQ
LYFSGYGVTLDDLKNFRGGAATRTPGHPEYGLTPGIEMTTGPLGQGFASAIGFAYGERFQRGLLDPETPKEDSPFYHKIW
AICGEGDIEEGISGEAASLAANQKLGNLTVIFDANRIQIEGDTNLVLAEDVLKRFQAYGWYTDEFSFIQPDGSYKEDIEG
LADVIAKAEKAAPDQPKLIKVHSLIAWPTPGKTNDPSSHGSKLGTEAVAGLKEALGYDPEENFHVDEEALAHARKVAERG
LEAHKEWDEKFDAWRKANPDKAALYDRLKAGELPEGFDKALDDLEATFEVGKGVATRGASGSVLNAIAAVMPELWGGSAD
LGGSNKTDLKGAATFAPAECATKQWPNCNEFGRQLHFGVREFTMGCITNGILLGSHTRPFGGTFFMFSDYERSAVRLAAL
MEIPNLYIWSHDSVAVGEDGPTHQPVEHLASFRAIPQLEVIRPADAFETAEAYRYFFEKKNTLPGAMVLTRQGVPVLAET
AAKAKDGVKKGAYVLVDTEGTPDVILMASGSEVQWAVAAAKTLAGEGVKARVVSVPSMEWFEEQDAEYKEAVLPAAVKAR
VSVEAGVAMPWYKYLGSYGKPVSIEQFGLQGDGAQNMIDLGITAEHVVEAAKASIAEVEAAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-99 41
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-98 41