Gene Information

Name : BL0712 (BL0712)
Accession : NP_695895.1
Strain : Bifidobacterium longum NCC2705
Genome accession: NC_004307
Putative virulence/resistance : Unknown
Product : bifunctional HTH-domain containing protein/aminotransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 490086 - 491630 bp
Length : 1545 bp
Strand : +
Note : in Corynebacterium glutamicum the aminotransferase can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; this protein contains a helix-turn-helix domain at the N-terminus

DNA sequence :
GTGTTTGCGGAACGTCTGCGCAATGCGATGAACAGCAGGGGACTGAAGCAGGTCGATTTGGTGCACGCCGCCGAACATCG
TGGTGTAAAGATGGGCAAGAGCCACATCAGCCAATACGTGGCCGGCAAGACCATGCCCCGCGAGGACGTGCTCGAATTCC
TGGCCAGCGAACTGGACGTCGACATGAACTGGCTGCGCGGCGAGGAATCCACCACGCAATTGAACTCGGACGCCTCCAAC
AGCGTCACGGACGGCGAACACGCCGCCACACCGCTTGCCACGGGTGCCTCCAAGCCCCAGACGGACAGCGAGATTCCCGT
GGGCCGCCGCCGCACCTTCGGCAAATCGCACAAGCTCGACAACGTGCTCTACGACGTGCGCGGCCCGGTCGCCGACGAGG
CGATGCGCATGGAGGCCAACGGCACCCACATCCTGAAATTGAACATCGGCAACCCGGCACCCTTCGGCTTCCGCACGCCG
GACGAAGTCGTCTACGACATGGCCCACCAGCTCACCGACACCGAAGGCTACTCGCCGTCCAAGGGCCTGTTCTCCGCGCG
CAAGGCCATCATGCAGTACGCGCAGCTGAAGAACATCCCGAACGTCACCATCGACGACATCTACACCGGCAACGGCGTCA
GCGAGCTCATCAACCTGTCCATGTCCGCGCTACTCGACACCGGCGACGAAGTGCTCGTGCCATCCCCGGACTACCCGCTG
TGGACCGCCTGCGTGAACCTGGCCGGCGGCACCGCCGTGCACTACCTGTGCGACGAACAGTCCGAATGGTATCCGGACAT
CGACGACATCCGCTCCAAGATCACCAGCAACACCAAGGCGATTGTCATCATCAACCCGAACAACCCCACCGGCGCACTTT
ACCCAAAGGAAGTGCTCCAGCAGATCGTCGACATCGCGCGCGAACACCAGCTCATCATCTTCTCCGACGAAATCTACGAT
CGCCTCGTCATGGACGGCCTGCAGCACATCTCCATCGCCTCGATGGCCCCGGACCTGTTCTGCGTGACCTTCTCCGGCCT
GTCGAAATCGCACATGATCGCCGGCTACCGCATCGGCTGGATGATCCTGTCCGGCAACAAGCGCATTGCCAAGGACTACA
TCGAGGGCCTCAACATGCTCGCCAACATGCGCATGTGTTCGAACGTGCCCGCCCAGTCCGTGGTGCAGACCGCGCTTGGC
GGCCACCAGAGCGTCAACGACTACATCGTGCCGGGCGGCCGCGTGCACGACCAGCGCGACCTCGTCTACGACATGCTCAA
CCAGATTCCCGGCATCACCGCCGTCAAGCCGAAGGCCGCGTTCTACATCTTCCCGAAGATCGACGTCAAACGCTTCAACA
TCCACTCGGACGAGCAGTTCGCGCTCGACCTGCTGCATGACAAGCACATCCTCATCAGCCACGGCGGCGCGTTCAACTGG
CATCGCCCCGACCACTTCCGCGTGGTGTACCTGCCGCGCATGGGCATGCTGCGCGAAACCATGGGGGAGATCTCCGACTT
CTTCAGCTACTACTGGCAGAGCTGA

Protein sequence :
MFAERLRNAMNSRGLKQVDLVHAAEHRGVKMGKSHISQYVAGKTMPREDVLEFLASELDVDMNWLRGEESTTQLNSDASN
SVTDGEHAATPLATGASKPQTDSEIPVGRRRTFGKSHKLDNVLYDVRGPVADEAMRMEANGTHILKLNIGNPAPFGFRTP
DEVVYDMAHQLTDTEGYSPSKGLFSARKAIMQYAQLKNIPNVTIDDIYTGNGVSELINLSMSALLDTGDEVLVPSPDYPL
WTACVNLAGGTAVHYLCDEQSEWYPDIDDIRSKITSNTKAIVIINPNNPTGALYPKEVLQQIVDIAREHQLIIFSDEIYD
RLVMDGLQHISIASMAPDLFCVTFSGLSKSHMIAGYRIGWMILSGNKRIAKDYIEGLNMLANMRMCSNVPAQSVVQTALG
GHQSVNDYIVPGGRVHDQRDLVYDMLNQIPGITAVKPKAAFYIFPKIDVKRFNIHSDEQFALDLLHDKHILISHGGAFNW
HRPDHFRVVYLPRMGMLRETMGEISDFFSYYWQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 6e-119 56
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 6e-119 56
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 6e-119 56
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 6e-119 56