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Name : leuS (BL1450) Accession : NP_696609.1 Strain : Bifidobacterium longum NCC2705 Genome accession: NC_004307 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 371339 - 374302 bp Length : 2964 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAGTGACAACGAGAAGAGCACGCAAACCGAAGAGCCCAACTTCCGCTACAACGCCGCACTGGCGCAGGACATCGAAAA CAAGTGGCAGAAGATTTGGGACGAGCAAGGCACCTTCTGGGCCGCCAACGTCAACGGCGATTTGAAGGACGGCAAGGGCC GTAACGCCGAAGGCCGCACCGCCTACTTCGCCATGGACATGTTTCCCTACCCGTCCGGCAAGGGCCTGCACGTCGGCCAC CCGCTGGGCTACCTGGCCTCCGACGTGGTGAGCCGCTACCACCGCATGAAGGGCGAGAACGTCCTGCACGCCATGGGTTA CGACGCCTTCGGCCTGCCTGCCGAACAGTACGCAGTCCAGACCGGCCAGCACCCGCGCGTGACCACTGAGGCGAACATCG CCAACATGAGCCGCCAGCTGCACCGTATGGGCCTGAGCTTCGACAACCGTCGTACGTTCGCCACCATCGACCCCGGCTAC GTGCGCTGGACCCAATGGATCTTCTCGCGCATCTACGATTCCTGGTACGACGAGGACGCCACCAACCCGTCCGGCTCCAA GGGCTCCGCACGCCCGATCGCCGAGCTCGTGGCCAAGTTCGAATCCGGCGAAAAGGCCATTCCGGGCCACGAGTCCGATG GCAAGCAGTGGTCCGACCTCACTGACGCCGAGCAGCAGGATATCTTGAACGACTTCCGCCTGGCCTACATCTCCAAGTCC CCGGTCAACTGGTGCCCGGGTCTGGGCACCGTGCTGGCCAACGAAGAGGTCACCGCCGAAGGTAAGTCCGAGCGTGGCAA CTTCCCGGTCTTCCAGCGTGAGCTACGCCAGTGGTCCATGCGCATCACCAAGTACGGCCACCGCCTCATCGCCGATCTTG ACGGCATCAACTGGCCTGAGAAGGTCAAGCTCATGCAGCGCAACTGGATCGGTGAATCCCATGGTGCCTCCGTGCACTTC ATCGTGGCCACTGCCGACGGTGACAAGGACATGGAAATCTACACCACCCGTCCCGACACGCTGTTCGGCACCACGTTCGC CGTGGTTTCCCCGGAACATCACCTGCTGGAGAACGTGCCCGCCGAATGGCCGGCCGATGTACCCGAAGACTGGAAGGGCG GCTATGCCAACCCGGTCGAGGCGGTGAAGGCCTACCGTCTGGCCGCCGAAGCCAAGACCGCCAAGGACCGCGTGAACGAG GCCGGTGAGAAGACCGGTCTGTTCACCGGCCTGTACGCCACCAACCCGATCACCGGCGCGAAGCTCCCGCTGTTTACTGC CGACTACGTGCTGATGGACTACGGCACCGGTGCCATTATGGCCGTGCCTGGTGGCGACCAGCGCGATTACGACTTTGCCG TGAAGTTCGGTCTGCCTGTCATCTACACCGTCACGCCTCTGCCGGATTCCGGCGACGACTTGGCCAACTACGAGGGCAAG GCGCCGTTCGTCTCCCATGACGGCATCGTGATCAACTCCTCCGTCGAGGCCACCGAAGCCAAGGGCGACGCGCTGAGCCT TAACGGCCTGCGCGTGGACGACGCCATCGCCAAGGTCAACGCCTGGCTCGAATCCGCCGGCGTGGGCAAGGGCACCGTAA GCTACCGTCTGCGCGACTGGCTGTTCTCCCGCCAGCGCTACTGGGGCGAGCCCTTCCCGATCGTCTACGGCGAAGACGGC ACCCCGCACCTGCTGCCGGATTCCGCATTGCCGATCAACCTGCCCGACGTGCCCGACTATGAGCCGCGCACCTTCGATCC GATGGACGCAGAGTCCAACCCGGAGGCACCGTTGAGCCGCAACGAGGACTGGGTCAAGGTCGAGCTCGACTTGGGCGACG GCAAGAAGACCTACTACCGCGACACCAACACCATGCCGAACTGGGCCGGCTCCTGCTGGTACTACATGCGTTACATCGAC CCGACCGACACCAAGCACATGGTGGAGAAGGACGAGTTCGACTACTGGATGGGCCCGAACCACAACAAGTACTCGGGTGA TGAAGGCGGTGTGGACCTGTACATCGGCGGCGTCGAACACGCTGTGCTCCACCTGCTCTACTCCCGCTTCTGGCACAAGG TGCTCTTCGACCTCGGCTACGTGGACTCGGCCGAACCGTTCCACAAGCTGTTCAACCAGGGCATGATCCAGGCCTACGCC TACACCGACGACCGCGGCCAGTACGTGCCGGCCGACGAGGTCGTGGAAGGCCCGGCCGACGCCTCCGGCGAGCCGACCTT CACCTGGAACGGCGAACATGCCAACCGCGAGTTCGGCAAGATGGGCAAGTCCCTCAAGAACATCGTGACCCCGGACTACA TGTACGAGAACTACGGTGCCGACACCTTCCGCCTGTACGAAATGAGCATGGGCCCGCTGGACGAGTCTCGCCCGTGGAAC ACCCGCAACGTGGTCGGTGGCATGCGCTTCCTGCAGCGTCTGTGGCGCAATGTGGTCGATGAGACCACCGGCCAGGCCCA TGTGACTGAGGACACGCCGGACGAAAAGACCCTGAAGCTGCTCAACAACACGATTGCCGAAGTGACCGCGGAAATGGAAG GCATGCGCCCGAACACCGCCATCGCCAAGCTCATCGTGCTCAACAACCACCTGACCGGTCTGAAGGCTGTGCCGCGTGCC GCCGTGGAGCCGCTGATCCTGATGCTCGCGCCGATTGCCCCGCACATCTGCGAGGAGATGTGGAGCAAGCTCGGTCACGC CGAATCCCTGTCCGCCGAGCCGTGGCCGGTGGCCGACGAACGCTACGTGGGCCACGACACCGTGACCGCCGTGGTGCAGA TCAAGGGCAAGGTGCGCGCCAAGCTCGAAGTGCCGGTCGACATCGATCCGGCCGATCTCGAGAAGCAGGCGCTTGCCGCC GTCGCCGACCGTCTTGGCGGCAAGGAGCCGCGCAAGGTGATCGTCAAGGCCCCGAAGATCGTCTCCATCGTTCCCGCGGA GTGA Protein sequence : MSDNEKSTQTEEPNFRYNAALAQDIENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGH PLGYLASDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMGLSFDNRRTFATIDPGY VRWTQWIFSRIYDSWYDEDATNPSGSKGSARPIAELVAKFESGEKAIPGHESDGKQWSDLTDAEQQDILNDFRLAYISKS PVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADLDGINWPEKVKLMQRNWIGESHGASVHF IVATADGDKDMEIYTTRPDTLFGTTFAVVSPEHHLLENVPAEWPADVPEDWKGGYANPVEAVKAYRLAAEAKTAKDRVNE AGEKTGLFTGLYATNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVTPLPDSGDDLANYEGK APFVSHDGIVINSSVEATEAKGDALSLNGLRVDDAIAKVNAWLESAGVGKGTVSYRLRDWLFSRQRYWGEPFPIVYGEDG TPHLLPDSALPINLPDVPDYEPRTFDPMDAESNPEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYID PTDTKHMVEKDEFDYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQGMIQAYA YTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDYMYENYGADTFRLYEMSMGPLDESRPWN TRNVVGGMRFLQRLWRNVVDETTGQAHVTEDTPDEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRA AVEPLILMLAPIAPHICEEMWSKLGHAESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPADLEKQALAA VADRLGGKEPRKVIVKAPKIVSIVPAE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 8e-137 | 45 |
