Gene Information

Name : thyA (BL1665)
Accession : NP_696816.1
Strain : Bifidobacterium longum NCC2705
Genome accession: NC_004307
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2081581 - 2082381 bp
Length : 801 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCCCTATGAGGACCTGGTGCGCAAGATCCTGACCGAAGGCACGCTGAAGTCCGATCGCACCGGCACCGGCACGATTTC
CCTGTTCGGCCAGCAGATGCGCTTTGACCTGTCGAAGTACTTCCCGTTGCTGACCACCAAGACCGTGTTCTTCAAAGGCC
TGGCCTATGAGCTGCTGTGGTTTTTGAAGGGTTCCTCCAACATCAACTGGCTGCTGGAGCACAACGTGCATATTTGGGAT
GAGTGGGCGGACGAGAACGGCGATCTGGGCCCGGTCTATGGCGTGCAGTGGCGTTCCTGGCCCGCGCCGACCCCCGAGGA
CCCGAATCGCACCATCGACCAGATCTCCAATGTGCTCGACCTCATCAAGCATCATCCGGATTCGCGCCGCATGATCGTCT
CCGCGTGGAATCCGGCCGAGGTGGAGAAGATGGCGTTGCCGCCCTGCCACGCGCTCTTCCAGTTCTACGTGGCCGACGAC
AAGCTAAGCTGCCAGCTGTACCAGCGTTCCTGCGACATGTTCCTCGGCGTGCCGTTCAATATCGCCTCCTACTCGCTGCT
CACCATGATGATGGCGCAGCAGGCCGGGCTCAAGCCGGGCGAATTCGTCTGGACCGGCGGCGACTGCCATGTTTACGACA
ACCACGTCGACCAGTTCCTTGAGCAGCTGGGCCGCAAGCCCTACCCGTACCCGACCATCGAGATCCGTAAGGCCGATTCC
CTGTTCGACTACCAGTATGAGGACTTCAAGGTCGTCGGCTACCAGCATCACCCCACTATTAAGGCACCTGTTGCGGTCTG
A

Protein sequence :
MPYEDLVRKILTEGTLKSDRTGTGTISLFGQQMRFDLSKYFPLLTTKTVFFKGLAYELLWFLKGSSNINWLLEHNVHIWD
EWADENGDLGPVYGVQWRSWPAPTPEDPNRTIDQISNVLDLIKHHPDSRRMIVSAWNPAEVEKMALPPCHALFQFYVADD
KLSCQLYQRSCDMFLGVPFNIASYSLLTMMMAQQAGLKPGEFVWTGGDCHVYDNHVDQFLEQLGRKPYPYPTIEIRKADS
LFDYQYEDFKVVGYQHHPTIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-87 67