Gene Information

Name : clpB (BL1250)
Accession : NP_696415.1
Strain : Bifidobacterium longum NCC2705
Genome accession: NC_004307
Putative virulence/resistance : Virulence
Product : protease of ClpA/ClpB type
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1855630 - 1858299 bp
Length : 2670 bp
Strand : +
Note : ClpB; COG family: ATPases with chaperone activity, ATP-binding subunit; PFAM_ID: Clp_N; PFAM_ID: Clp_N; PFAM_ID: AAA

DNA sequence :
ATGGAACAGAAGTTCACCACTATGGCCCAAGAAGCCGTCGGCGACGCGATTCAGAGTGCGTCCGCCGCAGGAAACGCGCA
GGTCGAGACCCTGCACGTCATGGATGCGCTGCTGCGCCAGGAAAACGGCGTGGCGCGCTCTCTGATCGAGGCCGCGGGCG
GGGACCCGCAGGCCATCGGCGCGGCGGTGCGCAACGCTTTGGTCGCGCTGCCGAGCGCATCCGGATCCAGCACCTCGCAG
CCACAGGCCAGCCGCCAGCTGACCGCCGCCATCGCCCAGGCTGAGAAGGAAATGCAGCAGATGGGCGACGAATACGTCTC
CACCGAACATCTGCTTATCGGCATCGCGGCCAGCAAGCCGAACCAGTCGGCCGAAATCCTGGAGAAGAACGGCGTCACCG
CAGCCTCCCTGCGCAAGGCCGTACCCGGCGTGCGTGGTGGCGCGAAGGTCACCAGCCCGGACGCGGAAGGCTCGTACAAG
GCCCTGGAGAAGTACTCCACCGACCTGACGGCCGCCGCCAAGGAAGGCAAGCTGGACCCGGTCATCGGACGTGACCAGGA
AATCCGCCGCGTGATTCAGATCCTCTCCCGTCGTACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGA
CCGCCGTCGTGGAAGGCCTGGCCCAGCGTATCGTGGCGGGCGACGTGCCCACCACCCTGCAAGGCAAGAAGCTCATCTCC
CTTGACCTAGGCTCCATGGTGGCCGGCTCGAAGTACCGTGGCGAGTTCGAGGAGCGCCTGAAGAGCGTCCTGAACGAAAT
CAAGAACGCGGACGGCCAGATCATCACCTTCATCGACGAGATTCACACCATCGTCGGCGCGGGTGCGGCCGAAGGCTCGA
TGGACGCCGGCAATATGCTGAAGCCTATGCTGGCCCGTGGCGAGCTGCGCCTGATCGGCGCGACCACGCTGGACGAGTAC
CGCGAGAACATCGAAAAGGATCCGGCATTGGAACGCCGTTTCCAACAGGTGTTCGTGGGCGAGCCGAGCGTGGAAGACAC
CATCGCCATCCTGCGTGGCCTGAAGCAGCGTTACGAGGCGCACCACAAGGTGACGATCGGCGATGACGCGCTGGTCGCCG
CCGCGACCCTCTCGAACCGGTACATCTCAGGCCGTCAGCTGCCGGACAAGGCCATCGACCTGGTCGATGAGGCGGCTGCC
CACCTGCGTATGGAGCTCGACTCCTCGCCTGAGGAGATCGATGAGCTGCAGCGCAAGGTGACCCGTCTTGAAATGGAGGA
AATGCAGCTCAAGAAGGCCGAGGATCCTGCGTCCAAGGAGCGTCTGGGCAAGCTGCAAGCCGAACTTGCGGACACCCGTG
AGAAGCTCAGCGGTCTCAAGGCGCGTTGGGATGCGGAACAGGCTGGCCACAACAAGGTCGGCGACCTGCGTGCCAAGCTC
GACGACCTGCGCGTGCAGGCGGATAAGTATACCCGTGAAGGCAACTTGGCGGAGGCCTCGAAGATTCTGTACGGCGAGAT
TCCGTCCATTCAGAAGGAGCTTGCCGCCGCGGAGAGCGCGGATGCTGAATCTGCTGATGCCAGCGCGGCCAACCCGGCCG
ATGAGCCGATGGTCCCGGACCGTGTGGACGCCGACTCGGTGGCTGAGATCGTCTCCGACTGGACCGGCATTCCCGTCGGC
CGCCTGATGCAGGGCGAAAACGAGAAGCTGCTGCACATGGAGGACTACCTCGGCAAGCGTGTGATCGGCCAGAAGGAAGC
CATCGCCGCCGTGTCCGACGCGGTGCGCCGTTCGCGTGCCGGCATCTCCGACCCGAACCGTCCGACCGGATCGTTCCTGT
TCCTCGGCCCCACCGGTGTGGGCAAGACCGAACTGGCCAAGGCGCTCGCCGACTTCCTGTTCGACGACGAGAAGGCCATG
GTCCGCATCGACATGTCCGAATACATGGAGAAGGCTTCGGTCTCGCGCCTGATTGGCGCGGCGCCGGGCTACGTGGGCTA
CGAGCAGGGCGGCCAGCTGACCGAGGCCGTGCGCCGTCGCCCGTATTCCGTGGTGCTGTTCGACGAGGTCGAGAAGGCCA
ACCCGGAGATCTTCGACGTGCTGCTGCAGGTACTTGACGATGGTCGCCTGACCGATGGCCAGGGAAGGACCGTGGACTTC
AAGAACACGATCCTGATTATGACCTCTAACCTCGGCTCGCAGTTCCTCGTGAACGAGGACATGGACGCCGACGCCAAGAA
AAAGGCCGTGATGGACGCTGTCCACATGAACTTCAAGCCGGAGTTCCTGAACCGTCTGGACGACATCGTCATGTTCCACC
CGCTTACGCGCGAGGAGCTTGGCGGCATCGTGGATATCCAGGTGGCTGGCGTGTCCCAGCGTCTGACCGATCGCCGCATC
ACGCTGGACGTCACCGACTCGGCTCGCGAATGGCTTGCCAACACCGGTTACGACCCGGCTTATGGCGCTCGTCCGCTGCG
CCGCCTGGTACAGACCGAAGTGGGCGACCAGCTGGCCCGTATGCTGCTGGCCGGCAAGGTCCACGACGGTGACACCGTGC
TCGTCGACCAGACCGGCGGCGAACATCTGGAGCTCTCCGCTTGGGCGAGCGACCAGATTGTCTCCGACAATCCGGACGTG
AGCGTGGACAACGTCACCGAAGACAAGTGA

Protein sequence :
MEQKFTTMAQEAVGDAIQSASAAGNAQVETLHVMDALLRQENGVARSLIEAAGGDPQAIGAAVRNALVALPSASGSSTSQ
PQASRQLTAAIAQAEKEMQQMGDEYVSTEHLLIGIAASKPNQSAEILEKNGVTAASLRKAVPGVRGGAKVTSPDAEGSYK
ALEKYSTDLTAAAKEGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQGKKLIS
LDLGSMVAGSKYRGEFEERLKSVLNEIKNADGQIITFIDEIHTIVGAGAAEGSMDAGNMLKPMLARGELRLIGATTLDEY
RENIEKDPALERRFQQVFVGEPSVEDTIAILRGLKQRYEAHHKVTIGDDALVAAATLSNRYISGRQLPDKAIDLVDEAAA
HLRMELDSSPEEIDELQRKVTRLEMEEMQLKKAEDPASKERLGKLQAELADTREKLSGLKARWDAEQAGHNKVGDLRAKL
DDLRVQADKYTREGNLAEASKILYGEIPSIQKELAAAESADAESADASAANPADEPMVPDRVDADSVAEIVSDWTGIPVG
RLMQGENEKLLHMEDYLGKRVIGQKEAIAAVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKALADFLFDDEKAM
VRIDMSEYMEKASVSRLIGAAPGYVGYEQGGQLTEAVRRRPYSVVLFDEVEKANPEIFDVLLQVLDDGRLTDGQGRTVDF
KNTILIMTSNLGSQFLVNEDMDADAKKKAVMDAVHMNFKPEFLNRLDDIVMFHPLTREELGGIVDIQVAGVSQRLTDRRI
TLDVTDSAREWLANTGYDPAYGARPLRRLVQTEVGDQLARMLLAGKVHDGDTVLVDQTGGEHLELSAWASDQIVSDNPDV
SVDNVTEDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-102 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_696415.1 protease of ClpA/ClpB type VFG2084 Protein 4e-109 42