Gene Information

Name : guaA (OB0716)
Accession : NP_691637.1
Strain : Oceanobacillus iheyensis HTE831
Genome accession: NC_004193
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 760794 - 762329 bp
Length : 1536 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAAAATAATGAGTTAGTACTTGTACTTGATTTTGGAAGTCAATACAATCAGTTAATTACACGTCGAATTAGAGAATT
TGGCGTTTATAGTGAACTTCATTCTCATAAATTAACTGCTGAAGAAATCAAAGAAATGAATCCAAAAGGAATTATTCTTT
CTGGTGGACCGCATAGTGTTTATGATGAAAATAGTTTTCGCTGTGATGAAGGTATTTTTGAATTAGGAATTCCTGTATTA
GGAATTTGTTATGGAATGCAGTTAATGTCACTTCATTATGACGGTAAGGTTGAACGCTCTAAAAACCGTGAGTATGGTAA
AGCATTGATCGAACTAGATGGAGAGCCTGTACTATTTAAAGACACTCCAAAAGGACAGACGGTTTGGATGAGTCATGGAG
ATAAAGTCACTGCAGCACCACCATCTTTCAACATTGATGCAACAAGCCCTTCTACACCAATTGCAGCAATTAGTAATGTA
GAAAAGAACTTGTATGGTGTTCAATTCCATCCAGAAGTTCGCCACACGGAATACGGAAATGATTTATTAAATCGCTTTGT
ATTCGATGTATGCGGATGTACTGGAGATTGGTCAATTGAGAACTTCATTGATATGGAAGTGGAGAAAATTCAAGAAACCG
TTGGCGATCGTAAAGTATTATGTGCGCTAAGTGGTGGAGTAGACTCCTCTGTAGTTGCTGCTTTGATTCATAAAGCGATT
GGTGATCAACTAACTTGTATTTTCGTAGATCACGGTCTTCTTCGTAAAAATGAAGGAGATGATGTCATGAAAGTATTTGC
AGAAGACTTTCAGATGAATATTATCAAAGTCGATGCAAAAGATCGTTTCCTATTTAAATTAGAGGGTGTATCTGACCCAG
AATTAAAACGTAAAATTATTGGTAATGAATTTATCTATGTATTTGATGATGAAGCATCAAAACTGAAAGATATCGACTTC
CTGGCACAAGGTACTCTATATACGGATGTTATTGAAAGTGGTACGGATACAGCGCAAACCATTAAATCTCATCACAACGT
AGGTGGATTACCAGAAGATATGCAGTTTACGCTAATCGAGCCTTTAAATACGTTATTTAAAGATGAAGTTCGTGAACTAG
GATCTCAATTAGGCGTACCTGACCGTATTGTCTGGCGCCAACCATTCCCAGGACCTGGATTAGCTATCCGTATCCTTGGT
GAAGTAACCGAAGAACATTTAGAAATCGTTCGTGAATCGGATGCAATCCTACGTGAAGAAATTGCAAAAGCGGGTCTAGA
TCGTGATATTTGGCAATACTTCACCGTCCTACCGAACATTAAAAGTGTTGGAGTAATGGGGGATGCACGTACGTATGCTC
ATACAATCGGTATCCGTGCGGTAACTTCGATTGATGGAATGACTTCCGATTGGGCACGTATCCCATGGGACGTATTAGAA
AGAATTTCTACACGTCTTGTGAATGATGTAGATAATATTAACCGCGTTGTGTATGACGTAACGAGTAAGCCGCCTGCTAC
GATTGAGTGGGAGTAG

Protein sequence :
MENNELVLVLDFGSQYNQLITRRIREFGVYSELHSHKLTAEEIKEMNPKGIILSGGPHSVYDENSFRCDEGIFELGIPVL
GICYGMQLMSLHYDGKVERSKNREYGKALIELDGEPVLFKDTPKGQTVWMSHGDKVTAAPPSFNIDATSPSTPIAAISNV
EKNLYGVQFHPEVRHTEYGNDLLNRFVFDVCGCTGDWSIENFIDMEVEKIQETVGDRKVLCALSGGVDSSVVAALIHKAI
GDQLTCIFVDHGLLRKNEGDDVMKVFAEDFQMNIIKVDAKDRFLFKLEGVSDPELKRKIIGNEFIYVFDDEASKLKDIDF
LAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFTLIEPLNTLFKDEVRELGSQLGVPDRIVWRQPFPGPGLAIRILG
EVTEEHLEIVRESDAILREEIAKAGLDRDIWQYFTVLPNIKSVGVMGDARTYAHTIGIRAVTSIDGMTSDWARIPWDVLE
RISTRLVNDVDNINRVVYDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-134 52