Gene Information

Name : pykA (OB2171)
Accession : NP_693092.1
Strain : Oceanobacillus iheyensis HTE831
Genome accession: NC_004193
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2205640 - 2207400 bp
Length : 1761 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAGAAACACAAAAATCGTATGTACAATTGGTCCTGCATCAGAATCAATTGAAAAGTTAGAGCAACTTATTGAAGCAGG
AATGAACGTAGCTCGTCTCAACTTTTCTCATGGAGATTATGCAGAGCATGGCGCACGGATTGAAAATATCCGAAAAGCAG
CTAAAAATAAAAATAAAACAGTAGCAATTCTTTTAGATACTAAAGGACCAGAGATTCGTACTGGTAGCTTTAAAGAAGGT
AGAGCAGATCTTATGCAGGGCAACCCTGTAACAATCGCTATGGATGAAGTAGAGGGGACTGCTGAGAAATTCTCTGTTAC
ATACCAAGGGCTAATCAATGATGTACATGAAGGTTCAAAGATTCTTTTGGATGATGGACTTATTGAATTAGAAGTAAAAT
CTATTGATAAAAGTAAAGGTGAAATTGAAACTATTGCACTTAACTCTGGGGAAATAAAGAATAAAAAAGGTGTTAACGTT
CCTAATGTTTCTGTAAATCTACCCGGTATAACAGAAAAAGACACCAATGATATTATCTTTGGAATTGAACAGGGTGTTGA
TTTTATTGCTGCATCTTTTGTGCGTCGAGCTTCGGATATTTTAGAAATTAAAGAAGTGCTAGATCAGCATCAGGCACAGT
ATATAAAAATCATCCCTAAAATTGAGAACCAAGAAGGTGTCGATAATATCGATAGTATTCTTGAGGTAAGTGATGGATTA
ATGGTAGCTCGTGGTGATTTAGGAGTGGAGATCCCAGCTGAAGATGTACCATTGGTACAGAAAAAATTAATTAAGCAATG
TAATAATGCTGGAAAGCCAGTAATTACTGCTACACAAATGTTAGATTCGATGCAGCGTAATCCACGACCTACACGTGCAG
AAGCATCAGACGTTGCTAATGCGATTTTTGATGGCACAGATGCAATTATGCTTTCTGGAGAAACTGCTGCGGGAACCTAC
CCAGTAGAATCTGTACAAACAATGAGTAATATTGCACTAAAAGCTGAATCTGCATTAGATCATAAACAAATGTTAGAAGA
ACGTTCACAATATGTCGATATGACTATAACAGAAGCAATTAGTCAATCCGTTACGCACACAGCATCCAATTTAAATGTTG
ATACAATTATCACACCGACAGAAAGCGGACATACAGCTAGAATGATTTCTAAATACCGTCCGAAAGCTTCCATTCTAGCA
GTTACTTTTAACGAAGTAGTAAATCGTCAACTATCCTTAGTTTGGGGAGTGCATGCTGTTCTGGGTAAACCAGCGACGTC
TACTGACGAAATGCTAGAAATTGCAGTTGATAAAGGATTAAATACAGGAATCTGCAGTAGAGGAAGCCGTGTCATTATTA
CGGCTGGTGTACCTGTTGGAGAGAGTGGAACAACTAACCTGTTAAAAGTTCATGTGATTGGTGATGTGATTGCTAAAGGA
CAAGGAATTGGAAGAAGAAGTGCATATGGACATGCCGTATTTGCTAAAACGAATAAAGAAGCTTTAGAAAAAGTACAAGA
CGGTGATATTTTAGTAACCTATGCAACAGAAAAAGAAATGATGCCTGCAATTGAAAAAGCATCAGCTATTATTACAGAAG
AAGGTGGATTAACTTCTCATGCAGCTGTTGTCGGATTAAGTCTTGGAATTCCAGTAATTGTTGGGGTTGACAATGTATTT
GAAATTCTTCAAGATGGACAAGATATTACTGTAGATGGTAACCGTGGAGATATCTACGCTGGCCATGCAGGTGTATTGTA
A

Protein sequence :
MRNTKIVCTIGPASESIEKLEQLIEAGMNVARLNFSHGDYAEHGARIENIRKAAKNKNKTVAILLDTKGPEIRTGSFKEG
RADLMQGNPVTIAMDEVEGTAEKFSVTYQGLINDVHEGSKILLDDGLIELEVKSIDKSKGEIETIALNSGEIKNKKGVNV
PNVSVNLPGITEKDTNDIIFGIEQGVDFIAASFVRRASDILEIKEVLDQHQAQYIKIIPKIENQEGVDNIDSILEVSDGL
MVARGDLGVEIPAEDVPLVQKKLIKQCNNAGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGTY
PVESVQTMSNIALKAESALDHKQMLEERSQYVDMTITEAISQSVTHTASNLNVDTIITPTESGHTARMISKYRPKASILA
VTFNEVVNRQLSLVWGVHAVLGKPATSTDEMLEIAVDKGLNTGICSRGSRVIITAGVPVGESGTTNLLKVHVIGDVIAKG
QGIGRRSAYGHAVFAKTNKEALEKVQDGDILVTYATEKEMMPAIEKASAIITEEGGLTSHAAVVGLSLGIPVIVGVDNVF
EILQDGQDITVDGNRGDIYAGHAGVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-108 52
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-108 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-108 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-107 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA NP_693092.1 pyruvate kinase VFG0479 Protein 3e-108 52