Gene Information

Name : thyA (OB1740)
Accession : NP_692661.1
Strain : Oceanobacillus iheyensis HTE831
Genome accession: NC_004193
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1780213 - 1781166 bp
Length : 954 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGTTAGGGGAACAAGCCTACTTAGATTTGTGTAAACAAATATTTAAAACTGGAGAACAACGTGGAGATCGAACCAATAC
AGGAACACATTCTATATTCGGACATCAAATTCGTTTTGATTTAAATAAAGGATTTCCTCTTCTAACGACAAAACGTGTTC
CATTCCGACTAGTTGCGAGTGAACTACTTTGGTTTATTAAAGGGGATACCAATATTCGGTATTTATTAAAACATAATAAT
AATATTTGGAATGAATGGGCATTTGAAAAATGGGTAAATAGCGCTGATTATCAAGGTCCAGATATGGCGAATTTCGGATT
ACGCAGTCAAAAAGATGAGAATTTTAATAAACAATATCAAGAACAAATGGAGCTCTTTAAAACGCGAATTCTTGAAGATG
ATTCTTTTGCTGACAAATACGGGGACTTAGGATCTGTATACGGGAAACAATGGAGAAATTGGAAGACTACTCAGAATGAA
ACAATTGATCAATTAAAAGATGTGATTCATTCCATTAAAACGAATCCAAATTCAAGAAGACATATTGTATCTGCGTGGAA
TCCAGAAGATATTCCAACAATGGCTTTACCTCCTTGTCATACATTATTCCAATTTTATGTTTCAAATGGAAAGCTTTCTT
GTCAGCTATACCAAAGAAGTGCAGACGTATTCCTAGGGGTACCATTCAATATAGCCAGTTATGCCCTACTCACGCATTTA
ATTGCCCATGAGTGTGGATTAGAAGTTGGTGATTTCGTACATACTTTTGGAGACGCACATATTTACTCTAATCATGTTGA
ACAAGTCGAAACACAACTGGAAAGGGAGATCCGCGATTTTCCACAACTAATAATAAACAAAGATAAAAATTCTATTTTTG
AAATGGACTTAGATGATTTAGTGATTGAAAATTATAATCCTCATCCAAGTATTAAAGCACCGATTGCTGTATAG

Protein sequence :
MLGEQAYLDLCKQIFKTGEQRGDRTNTGTHSIFGHQIRFDLNKGFPLLTTKRVPFRLVASELLWFIKGDTNIRYLLKHNN
NIWNEWAFEKWVNSADYQGPDMANFGLRSQKDENFNKQYQEQMELFKTRILEDDSFADKYGDLGSVYGKQWRNWKTTQNE
TIDQLKDVIHSIKTNPNSRRHIVSAWNPEDIPTMALPPCHTLFQFYVSNGKLSCQLYQRSADVFLGVPFNIASYALLTHL
IAHECGLEVGDFVHTFGDAHIYSNHVEQVETQLEREIRDFPQLIINKDKNSIFEMDLDDLVIENYNPHPSIKAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-111 70