Gene Information

Name : dhbE (OB0956)
Accession : NP_691877.1
Strain : Oceanobacillus iheyensis HTE831
Genome accession: NC_004193
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1002550 - 1004169 bp
Length : 1620 bp
Strand : +
Note : CDS_ID OB0956

DNA sequence : 
ATGCTAGAAGGGTATAAGCCATGGCCAGAGAATCTTAGAAAGTACTATCAAGAAACTGGTTGCTGGACGGGAGAGACTTT
CGGAGGAATATTAGAGCAACAAGCTAGAGACAGAAAAGACAGTATTGCGATTACTGATGGAGAGAAATCCATTACGTATC
AGCAATTAGATGAAAGAGTAAACAAACTAGCTGCAGGATTCATGAAATTAGGTATAGAGAAAGAAGATAGAGTAGTTCTT
CAACTACCAAATACTATTGAATTTTTTGAGGTTTGTTTCGCGTTATTTCGAATTGGTGCTTTACCTGTTTTTGCTCTACC
GCTGCATCGAAAAATGGAAATTAGTTATTTCTGTGAATTTACAGCAGCTAAAGCGTATATCATTCCAGATGTATTCGATA
AATTTGACTACAGAGATCTAGCAAATGAAATAAATAACTCTATTCCTACTCTGGAGCATACGATTGTTGCAGGTGAAACA
GATAATTTTATTTCATTAGAAGAATTATATATGGATGATTCAGCATCTTTTCCAACTATTACTGGAAGTGATTTAGCTTT
TTTCCAATTATCAGGTGGAAGTACTGGATTACCTAAACTAATTCCGCGTACACATGATGAGTATATTTATAGTCTTCGGA
AAAGTGTGGAAATATGTCGAATTAGTCAAGATACGAATTTCTTAGCGGTTCTACCTGTTGCACATAATTTTACGATGAGT
TCACCAGGAGTTTTTGGTGTCATATATGCTGGTGGGAAAATTATTCTAAGTAAATATCCTAGTCCTGATGTGGCTTTTCC
GTTAATAGAAAAGGAGAAAGTAGATTTCACATCATTGGTTCCACCATTAGCGATTGTATGGTTACAAGCGCAGAAAAGGA
CAAAAGCAGATTTACGTTCGTTGGAAGTCATTCAAGTTGGTGGAGCAAAATGCAGTGTTGAAGTTGCGAAACAAATTGGC
CCGGCGTTTCACTGTAAATTACAGCAAGTATTTGGTATGGCAGAAGGCCTAGTAAATTATACGAGATTAGATGACGACGA
TGAAGTAGTTATTCATACACAAGGCAAACCGATGTCAGCGTATGATGAAATTCGTATTGTGGATGAAGAAGATAATGAGC
TACCAGTAGGAGAAACAGGACAACTTCAAGCGAGAGGTCCATATACCATCATTGGTTATTTCAATGTAGAAGACCATAAT
GCAAAAGCTTTTACTTCGGATGGTTTTTATCGCACTGGAGATTTAGTCAAACTAACGGAGGAAGGGTATCTAATCGTTGA
AGGAAGAGATAAGGATCAAATTAATCGTGGTGGCGAAAAAATTGCCGCAGAAGAGGTAGAAAATTATATCCTATCACTTT
CAGGCATACATGATGTAGCAATGGTGAGTATGCCAGACAAATTTCTTGGAGAAAGGTCTTGTGCCTTTGTCATAAAAAAT
GATGAAGAATTAACGAGCAATGACATAAAGGATTTCTTACAGCATAAAGGAATAGCTAATTTTAAAATCCCAGATCGGAT
AGAATTCGTGGATCGTTTTCCATATACAGCACTAGGTAAGGTGAGTAAGAAAAACTTAAGAGCAATGATAAAAGAAAAAA
TCACACAAAAAAGTTATTAA

Protein sequence : 
MLEGYKPWPENLRKYYQETGCWTGETFGGILEQQARDRKDSIAITDGEKSITYQQLDERVNKLAAGFMKLGIEKEDRVVL
QLPNTIEFFEVCFALFRIGALPVFALPLHRKMEISYFCEFTAAKAYIIPDVFDKFDYRDLANEINNSIPTLEHTIVAGET
DNFISLEELYMDDSASFPTITGSDLAFFQLSGGSTGLPKLIPRTHDEYIYSLRKSVEICRISQDTNFLAVLPVAHNFTMS
SPGVFGVIYAGGKIILSKYPSPDVAFPLIEKEKVDFTSLVPPLAIVWLQAQKRTKADLRSLEVIQVGGAKCSVEVAKQIG
PAFHCKLQQVFGMAEGLVNYTRLDDDDEVVIHTQGKPMSAYDEIRIVDEEDNELPVGETGQLQARGPYTIIGYFNVEDHN
AKAFTSDGFYRTGDLVKLTEEGYLIVEGRDKDQINRGGEKIAAEEVENYILSLSGIHDVAMVSMPDKFLGERSCAFVIKN
DEELTSNDIKDFLQHKGIANFKIPDRIEFVDRFPYTALGKVSKKNLRAMIKEKITQKSY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE CAA21394.1 - Virulence HPI Protein 5e-114 47
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 9e-114 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 4e-114 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-113 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 6e-114 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-114 47
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 5e-114 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-114 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-114 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE NP_691877.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-130 49
dhbE NP_691877.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 1e-109 45
dhbE NP_691877.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 3e-105 41