Gene Information

Name : czcR (PFL_5221)
Accession : YP_262298.1
Strain : Pseudomonas protegens Pf-5
Genome accession: NC_004129
Putative virulence/resistance : Virulence
Product : DNA-binding heavy metal response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 5980645 - 5981319 bp
Length : 675 bp
Strand : +
Note : identified by similarity to SP:O31395; similarity to GB:CAB56468.1; match to protein family HMM PF00072; match to protein family HMM PF00486; match to protein family HMM TIGR01387

DNA sequence : 
ATGCGTATTCTGGTCATCGAAGACGAACCCAAGACCGCTGACTACCTGCATCAGGGGCTGACTGAAAGTGGCTACGTGGT
GGATTGCGCCAACAACGGCGCGGACGGCCTGCACCTGACTCGCCAGCATGCGTACGACCTGGTGATCCTCGACATCAACC
TGCCGCACATCGACGGCTGGGGCGTGCTCGGGCAGATCCGCCAGGACAGCAGCACCCGGGTGATGATGCTCACCGCCCAG
GGCCGGCTGGCGGACAAGATCCGTGGCCTGGACCTGGGCGCCGACGATTACCTGGTCAAGCCGTTCCAGTTTCCGGAATT
GCTGGCCCGGGTCCGCACCCTGATGCGCCGCAGCGAACAGGCGCCGGTGCCGGATGTTCTGCGGGTCGCCGACCTGGAGC
TGGACCAGGGCCGGCACCGGGCCTTTCGCGGCAAGCAGCGCATCGACCTGACCACCAAGGAGTTCGCCCTGCTGCACCTG
CTGATGCGCCAGAGCGGCGTGGTGCTGTCGCGGACCCAGATCATTTCCTTTGTCTGGGACATGAATTTCGACTGTGACAC
CAATGTGGTGGAAGTCTCGATCCGCCGCCTGCGGGCGAAGATCGACGACCCTTTCGAACGCAAACTGATCCACACCCTGC
GCGGTGTGGGTTATGTCCTTGAAGAACGCGACTGA

Protein sequence : 
MRILVIEDEPKTADYLHQGLTESGYVVDCANNGADGLHLTRQHAYDLVILDINLPHIDGWGVLGQIRQDSSTRVMMLTAQ
GRLADKIRGLDLGADDYLVKPFQFPELLARVRTLMRRSEQAPVPDVLRVADLELDQGRHRAFRGKQRIDLTTKEFALLHL
LMRQSGVVLSRTQIISFVWDMNFDCDTNVVEVSIRRLRAKIDDPFERKLIHTLRGVGYVLEERD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 6e-54 52
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 2e-53 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
czcR YP_262298.1 DNA-binding heavy metal response regulator BAC0125 Protein 1e-65 61
czcR YP_262298.1 DNA-binding heavy metal response regulator BAC0197 Protein 7e-63 58
czcR YP_262298.1 DNA-binding heavy metal response regulator BAC0083 Protein 5e-59 57
czcR YP_262298.1 DNA-binding heavy metal response regulator BAC0638 Protein 1e-55 57
czcR YP_262298.1 DNA-binding heavy metal response regulator BAC0308 Protein 2e-57 54
czcR YP_262298.1 DNA-binding heavy metal response regulator BAC0111 Protein 1e-59 52
czcR YP_262298.1 DNA-binding heavy metal response regulator BAC0347 Protein 2e-55 51
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_003923.1003417.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_013450.8614146.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_002951.3238224.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_007793.3914065.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_002758.1121390.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_010079.5776364.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_002952.2859858.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator NC_007622.3794948.p0 Protein 5e-39 44
czcR YP_262298.1 DNA-binding heavy metal response regulator AE015929.1.gene1106. Protein 4e-34 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
czcR YP_262298.1 DNA-binding heavy metal response regulator VFG0596 Protein 2e-54 52
czcR YP_262298.1 DNA-binding heavy metal response regulator VFG1386 Protein 2e-37 43
czcR YP_262298.1 DNA-binding heavy metal response regulator VFG1389 Protein 2e-34 42
czcR YP_262298.1 DNA-binding heavy metal response regulator VFG1390 Protein 2e-37 41