Gene Information

Name : megL (PFL_3514)
Accession : YP_260617.1
Strain : Pseudomonas protegens Pf-5
Genome accession: NC_004129
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 4048510 - 4049763 bp
Length : 1254 bp
Strand : +
Note : identified by similarity to SP:P13254; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF06838; match to protein family HMM TIGR01328

DNA sequence :
ATGAACAATAAAAACAGTGACCTTGGTTTTTCCACCCGTGCCATCCATCACGGCTACAACCCCCAGGAGCATCAGGGCGC
GCTGATCCCGCCGATCTACCTGACCTCCACCTTCACCTTCGCCACCGCCGAATACGGCGCCGGCTGTTTTGCCGGTGAAG
AACCCGGCTACTTCTATACCCGCATCGGCAACCCGACCCTGGCGTTGCTGGAAGCGCGCATGGCCGCCCTGGAAAACGGC
GAAGCGGCCGTGGCGTTCGGCTCCGGCATGGGGGCGATTGCCGCGACCTTGTGGACCCTGCTGCGCCCGGGCGACGAGGT
CATCGTCGGCCAGACTTTGTACGGTTGCACCTTTGCCCTGCTGCACCACGGCCTTGGCGAATTCGGCGTCAAGGTACGCC
ATGTCGACCTGACCGACCTGGGCGAGCTACGGGCGGCCATCGGCCCGGCCACGCGGATGATCTATTTCGAAACCCCGGCC
AACCCCAACATGCAACTGGTGGACATCGCCGCCGTGGCCCAGGTGGCCCGCCAGCATCCCGGCCTGCTCGTGGCGGTGGA
CAACACCTACTGCACACCTTACCTGCAGCGCCCGCTGGAACTGGGCGCCGACCTGGTGCTGCATTCGGCCACCAAGTACC
TCAGCGGCCATGGCGACATCACCGCCGGCATCGTGGTCACCGGCCAGGCCCTGGCCGAACGCATCCGCCTGCAGGGCCTG
AAGGACCTGACCGGCGCGGTGCTCTCGCCCCAGGACGCTTTTCTCCTGATGCGCGGCCTCAAGACCCTGGCCCTGCGCAT
GGATCGCCATTGCGCCAACGCCCAGGCCGTCGCCCAGTTCCTCCAGGACCACCCCGCCGTGGCCTGGGTCGCCTACCCGG
GGCTGGCATCCTTTGCCCAACACGCCCTGGCCGCAAGACAGATGAAGCTGCCCGGCGGCATGATCGCCTTCGAACTCAAG
GGTGGGCTGGCCAGCGGGCGACGCTTCATGAACGCCCTGGGGCTGTTCAGCCGCGCGGTCAGCCTGGGGGATGCCGAATC
CCTGGCCCAGCACCCGGCGAGCATGACCCATTCCACCTACACCCAGGAGGAACGGGCCGAACACGGCATCGCCGAGGGCC
TGGTACGGCTGTCGGTGGGGCTGGAAGACATCGCCGACCTGCTGGCCGACATCGCCCAGGCCCTGGACGCCAGCGCCGAA
CCCGCGCGCCCCACCCTGGAGGCCGTGAGCCGAATCGGCAAGGCCCTGCCTTGA

Protein sequence :
MNNKNSDLGFSTRAIHHGYNPQEHQGALIPPIYLTSTFTFATAEYGAGCFAGEEPGYFYTRIGNPTLALLEARMAALENG
EAAVAFGSGMGAIAATLWTLLRPGDEVIVGQTLYGCTFALLHHGLGEFGVKVRHVDLTDLGELRAAIGPATRMIYFETPA
NPNMQLVDIAAVAQVARQHPGLLVAVDNTYCTPYLQRPLELGADLVLHSATKYLSGHGDITAGIVVTGQALAERIRLQGL
KDLTGAVLSPQDAFLLMRGLKTLALRMDRHCANAQAVAQFLQDHPAVAWVAYPGLASFAQHALAARQMKLPGGMIAFELK
GGLASGRRFMNALGLFSRAVSLGDAESLAQHPASMTHSTYTQEERAEHGIAEGLVRLSVGLEDIADLLADIAQALDASAE
PARPTLEAVSRIGKALP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-57 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-58 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-48 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_260617.1 methionine gamma-lyase BAC0207 Protein 4e-137 76