Gene Information

Name : polA (SAG0389)
Accession : NP_687423.1
Strain : Streptococcus agalactiae 2603V/R
Genome accession: NC_004116
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 397169 - 399811 bp
Length : 2643 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGACAAACAAGAATAAATTACTTTTAATTGATGGCTCATCTGTAGCCTTTCGTGCTTTTTTTGCTCTTTATAATCAAAT
TGACCGCTTTAAAAACAATTCTGGACTTCATACTAATGCCATATATGGTTTCCATTTGATGTTGAATCATATTTTAGGTC
GTGTCCAGCCTAGTCATATTTTAGTGGCTTTTGATGCCGGAAAAACTACTTTCCGTACGGAAATGTATGCAGATTATAAA
GGTGGGCGTGCTAAAACTCCGGATGAATTTCGTGAACAATTTCCTTACATTCGTCAACAATTAGATGTCTTAGGCATCAA
ACATTATGAATTGGAACATTATGAAGCCGATGATATCATTGGTACTCTTGCAAAACAAGCCGAAGCTAGTAATGAACATT
TTGATATAACGGTGGTTTCTGGGGATAAAGATTTAATTCAATTAACAGACACTAACACGGTAGTAGAAATCTCTAAAAAG
GGAGTTGCTGAGTTTGAAGAATTCACGCCAGCTTACCTTATGGAAAAAATGGGAATTACGCCGAGTCAATTTATTGATTT
AAAAGCTTTGATGGGAGATAAATCAGATAATATTCCTGGGGTTACTAAAATCGGTGAAAAAACTGGCTTGAAGTTGCTAT
CAGAATATGGTTCCTTAGAAGGGATCTATGAAAATATTGAGGCTATGAAACAGTCTAAGATGAAAGAAAACCTTATCAAT
GATAAGGAGCAAGCTTTCTTATCAAAGACCCTAGCTACAATCAACATAGCATCACCTATAACAATCGGCTTAGAAGATAT
CCTTTATAGTGGACCGCAAGATATAAAAGCCTTGTCTCAATTTTATGATGAGATGGATTTTAAACAGTTTAAAGCAGCTC
TGGGTGAGGAGACAAGTCAGGAAGATTTTGAGGTTGACTTTACTGAAGTGGAGCAATTAAAAACAGAAATGTTCTCCGAT
AATGATTTTTATTACTTTGAGATGTTGGGTGATAACTACCATGTAGAAGATTTAATTGGGATAGCTTGGGGAAATAGCGA
TACAATCTACGCTACTAGTAATGTATCGTTATTGCAAGAAGCTTTATTTAAAAAAGCTTTATCAAAACCTATCAAAACTT
ATGATTTTAAAAGAAGTAAGGTCCTTTTAAATCGTTTTAATATTGATTTACCAGAGCCAGCCTTTGATACTAGATTGGCC
AAGTACCTTTTGTCTACTACTGAGGATAATCTAGTATCAACAATTGCTAGGTTATATACAAATCTGCCACTGGATACTGA
TGATGCTGTTTATGGGAAAGGTGCTAAACGCGCTATACCAGAAAAAACACGATTTCTTGAGCATCTAGCTAAAAAAGTAA
AAGTTTTAGTGGATTCTGAGGCTAATATTATGCAACAGCTTAAAGCTAATGAGCAAGAAGAATTGCTGTTTGAAATGGAG
CAACCTTTAGCGAATGTTTTAGCTAAAATGGAAATTCGAGGTATTAAGGTTAAGAAAAATACCTTGAATGAAATGGCCAT
TGAAAATCAAAAAGTCATCGAAACATTAACACAAGAAATCTATGAATTGGCTGGGCAAGAGTTTAATATTAATTCTCCAA
AACAGTTAGGAAAGTTGTTGTTTGAAACGTTAGGTCTTCCTGTAGAAATGACTAAAAAAACAAAAACAGGTTATTCAACT
GCAGTAGATGTATTAGAGCGCTTAGCTCCGATTTCTCCTCTTGTAACTAAAATTTTAGAGTACCGTCAAATCACTAAATT
GCAATCAACCTATATTATTGGTTTACAAGATTATATTTTAGAAGATGGTAAAATTCATACACGTTATGTTCAAGATTTGA
CTCAGACAGGTCGTCTTTCAAGTTCTGACCCAAACCTTCAAAATATACCAGTTAGACTAGAGCAAGGACGGCTTATCCGA
AAAGCTTTTGTTCCATCAGAAGACAATGCTGTTTTATTGAGTTCAGATTATTCTCAAATAGAATTGCGCGTGTTAGCACA
TATTTCAAAAGACGAACATTTGATCGCTGCCTTTAAAGAGGGAGCTGATATTCATACTTCAACAGCTATGCGTGTTTTTG
GTATCGAAAAACCTGAGAATGTCACTCCCAATGATCGTCGAAATGCTAAGGCTGTTAATTTTGGAATTGTTTATGGTATT
TCAGATTTTGGTCTATCGCATAATTTAGGAATACCTCGTAAACTAGCGAAGCAATATATTGACACCTATTTTGAGCGTTA
TCCTGGAATAAAAAACTATATGGAAACAGTTGTTCGTGAAGCAAAAGATAAGGGTTACGTTGAAACACTTTTCCATCGTC
GTCGTTCATTACCAGATATTAATTCTCGTAATTTTAACATTCGCCAATTTGCAGAGCGCACAGCAATCAATTCACCAATC
CAAGGAAGTGCAGCTGATATTCTTAAAATTGCAATGATAAATTTAGATAGGGTACTTGATAAAGGTGGTTATAAATCAAA
AATGCTGTTGCAAGTTCATGATGAAATTGTACTTGAAGTCCCTAACGAGGAGATAGGAGCAATCAGGGAGTTGGTTACAA
AAACAATGGAGTCAGCAATTAGTTTATCGGTACCTTTGATTGCAGATGAGAACGCAGGTGAGACTTGGTATGAAGCGAAG
TAG

Protein sequence :
MTNKNKLLLIDGSSVAFRAFFALYNQIDRFKNNSGLHTNAIYGFHLMLNHILGRVQPSHILVAFDAGKTTFRTEMYADYK
GGRAKTPDEFREQFPYIRQQLDVLGIKHYELEHYEADDIIGTLAKQAEASNEHFDITVVSGDKDLIQLTDTNTVVEISKK
GVAEFEEFTPAYLMEKMGITPSQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLSEYGSLEGIYENIEAMKQSKMKENLIN
DKEQAFLSKTLATINIASPITIGLEDILYSGPQDIKALSQFYDEMDFKQFKAALGEETSQEDFEVDFTEVEQLKTEMFSD
NDFYYFEMLGDNYHVEDLIGIAWGNSDTIYATSNVSLLQEALFKKALSKPIKTYDFKRSKVLLNRFNIDLPEPAFDTRLA
KYLLSTTEDNLVSTIARLYTNLPLDTDDAVYGKGAKRAIPEKTRFLEHLAKKVKVLVDSEANIMQQLKANEQEELLFEME
QPLANVLAKMEIRGIKVKKNTLNEMAIENQKVIETLTQEIYELAGQEFNINSPKQLGKLLFETLGLPVEMTKKTKTGYST
AVDVLERLAPISPLVTKILEYRQITKLQSTYIIGLQDYILEDGKIHTRYVQDLTQTGRLSSSDPNLQNIPVRLEQGRLIR
KAFVPSEDNAVLLSSDYSQIELRVLAHISKDEHLIAAFKEGADIHTSTAMRVFGIEKPENVTPNDRRNAKAVNFGIVYGI
SDFGLSHNLGIPRKLAKQYIDTYFERYPGIKNYMETVVREAKDKGYVETLFHRRRSLPDINSRNFNIRQFAERTAINSPI
QGSAADILKIAMINLDRVLDKGGYKSKMLLQVHDEIVLEVPNEEIGAIRELVTKTMESAISLSVPLIADENAGETWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 76