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Name : tkt (SAG0278) Accession : NP_687313.1 Strain : Streptococcus agalactiae 2603V/R Genome accession: NC_004116 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 285165 - 287150 bp Length : 1986 bp Strand : + Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGACATTTGACACCATTGATCAATTAGCGGTTAATACAGTCCGCACGCTTTCTATTGATGCTATCCAAGCAGCAAATTC TGGGCACCCAGGTCTTCCTATGGGAGCTGCGCCTATGGCTTATGTGCTTTGGAATAAATTCTTAAATGTAAACCCAAAAA CAAGTCGCAATTGGACAAACCGTGACCGTTTTGTGCTATCAGCTGGGCATGGTTCAGCTCTTCTTTATAGCCTACTTCAT TTAGCTGGCTATGATTTATCAATTGATGATTTAAAACAATTTCGCCAATGGGGATCAAAAACACCTGGACATCCAGAAGT TAACCATACTGATGGTGTAGAAGCAACAACTGGACCTTTAGGGCAAGGTATTGCTAATGCTGTTGGTATGGCAATGGCTG AAGCTCATTTGGCTGCTAAATTTAATAAACCAGGCTTTGATTTAGTTGATCATTACACTTATACACTTCATGGTGATGGT TGTTTGATGGAGGGTGTTAGCCAAGAAGCTGCCAGTCTTGCTGGACACTTAAAACTTGGTAAATTGGTCCTTCTTTATGA TTCAAATGATATCTCACTTGATGGTCCAACATCTCAATCATTTACAGAAGATGTTAAAGGACGTTTTGAATCATATGGTT GGCAACATATCTTAGTTAAAGATGGTAATGATTTAGAAGCGATTGCTGCAGCAATTGAAGCTGCTAAAGCTGAAACTGAT AAACCAACCATTATTGAAGTTAAAACTATTATTGGATTTGGCGCAGAGAAACAGGGAACATCTTCAGTTCATGGAGCGCC ACTTGGTGCAGAAGGTATTACTTTTGCCAAGAAGGCTTATGTATGGGAATATCCAGACTTTACTGTTCCTGCTGAAGTTG CAGATCGATTTGCCTCAGATCTTCAAGCGCGTGGTGCGAAGGCAGAAGAGGCATGGAATGATCTTTTTGCTAAATATGAA GTTGAGTATCCAGAATTAGCAACTGAATACAAAGAAGCTTTTGCTGGCCAAGCTGAGACAGTTGAACTGAAAGCTCATGA CCTAGGTTCATCAGTGGCTAGTCGTGTTTCAAGCCAACAAGCTATTCAACAATTATCGACTCAATTACCGAACCTCTGGG GAGGGTCAGCAGACCTCTCAGCTTCTAATAACACAATGGTAGCAGCAGAAACAGATTTCCAAGCAAGTAACTACGCTGGG CGTAATATTTGGTTTGGTGTACGTGAATTTGCAATGGCTGCTGCAATGAATGGAATTGCGCTTCACGGTGGGACTCGTGT TTATGGGGGTACGTTCTTTGTCTTCTCAAACTACTTGTTACCAGCAGTACGTATGGCTGCACTTCAAAACTTGCCAACTG TCTATGTTATGACACATGATTCTATTGCTGTTGGAGAAGATGGGCCAACTCATGAGCCAATAGAACAATTAGCATCAGTG CGCTCAATGCCTAATTTGAACGTTATCCGTCCCGCAGACGGTAATGAAACAAACGCTGCATGGCAACGAGCTGTATCAGA GACAGATCGACCAACGATGCTTGTTTTAACACGTCAAAACTTACCAGTTCTTGAAGGAACATCAGAATTAGCCCAAGAAG GGGTTAATAAAGGTGCTTATATTTTATCAGAAGCTAAAGGTGAACTTGATGGTATCATCATTGCAACAGGTTCAGAAGTT AAATTAGCTTTAGATACTCAAGACAAACTTGAGTCAGAGGGCATCCATGTTCGCGTCGTATCTATGCCAGCACAAAACAT TTTTGATGAACAAGAGGCTTCATATCAAGAGCAAGTGCTTCCATCAGCTGTTACAAAACGTCTTGCTATTGAGGCAGGAT CAAGCTTCGGTTGGGGTAAATATGTTGGTTTAAATGGGCTAACACTTACTATTGATACTTGGGGAGCATCAGCACCAGGT AACAGAATTTTCGAAGAGTATGGCTTTACAGTTGAGAATGCTGTATCGCTATATAAAGAACTTTAA Protein sequence : MTFDTIDQLAVNTVRTLSIDAIQAANSGHPGLPMGAAPMAYVLWNKFLNVNPKTSRNWTNRDRFVLSAGHGSALLYSLLH LAGYDLSIDDLKQFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDLVDHYTYTLHGDG CLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSQSFTEDVKGRFESYGWQHILVKDGNDLEAIAAAIEAAKAETD KPTIIEVKTIIGFGAEKQGTSSVHGAPLGAEGITFAKKAYVWEYPDFTVPAEVADRFASDLQARGAKAEEAWNDLFAKYE VEYPELATEYKEAFAGQAETVELKAHDLGSSVASRVSSQQAIQQLSTQLPNLWGGSADLSASNNTMVAAETDFQASNYAG RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV RSMPNLNVIRPADGNETNAAWQRAVSETDRPTMLVLTRQNLPVLEGTSELAQEGVNKGAYILSEAKGELDGIIIATGSEV KLALDTQDKLESEGIHVRVVSMPAQNIFDEQEASYQEQVLPSAVTKRLAIEAGSSFGWGKYVGLNGLTLTIDTWGASAPG NRIFEEYGFTVENAVSLYKEL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 9e-142 | 52 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 3e-140 | 50 |
