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Name : leuS (SAG2057) Accession : NP_689043.1 Strain : Streptococcus agalactiae 2603V/R Genome accession: NC_004116 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 2034681 - 2037182 bp Length : 2502 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGACATTCTATAATCACAAAGAAATCGAACCCAAATGGCAAGCTTTTTGGGCAGATAATCATACCTTTAAAACAGGAAC AGACGCATCAAAACCTAAGTTTTATGCCCTAGATATGTTCCCATACCCATCTGGAGCTGGTCTCCACGTTGGTCACCCAG AAGGCTATACAGCAACGGATATTCTCAGCCGTTTCAAACGTGCCCAAGGTCACAATGTCCTCCACCCAATGGGTTGGGAT GCTTTTGGACTTCCTGCTGAGCAGTACGCTATGGATACTGGTAATGACCCAGCTGAGTTTACAGCTGAAAACATCGCTAA CTTCAAACGCCAGATTAATGCTCTTGGTTTCTCATACGACTGGGATCGTGAAGTTAACACAACTGACCCTAACTACTACA AGTGGACACAGTGGATCTTTACCAAGCTTTATGAAAAAGGTCTAGCTTACGAAGCTGAAGTTCCAGTTAACTGGGTTGAA GAATTGGGAACAGCTATCGCCAACGAAGAGGTTCTTCCAGATGGTACATCAGAACGTGGTGGCTACCCAGTTGTCAGAAA ACCAATGCGCCAATGGATGCTCAAAATCACTGCCTATGCAGAGCGCTTGCTGGAAGACTTGGAAGAAGTTGACTGGCCAG AGTCAATCAAGGACATGCAACGCAACTGGATTGGTAAATCAACTGGTGCTAATGTAACCTTCAAGGTTAAGGATACAGAT AAGGACTTCACTGTCTTTACAACACGTCCTGACACCCTTTTTGGTGCGACTTACGCAGTTCTTGCTCCTGAGCATGCCTT GGTTGATGCTATTACAACAGCTGACCAAGCAGAAGCCGTTGCCGAATACAAACGTCAAGCGAGTCTCAAATCAGACCTTG CTCGTACAGACCTTGCCAAAGAAAAAACTGGTGTCTGGACAGGTGCCTATGCCATTAACCCAGTTAATGGTAAAGAAATT CCAGTTTGGATTGCGGACTATGTCCTTGCTAGCTACGGTACAGGTGCTATCATGGCAGTTCCAGCTCACGATGAACGTGA CTGGGAATTCGCAAAACAATTCAACCTAGACATCATTCCAGTTCTTGAAGGTGGGAATGTTGAAGAGGCTGCCTTTACAG AAGACGGTCTTCACATCAACTCAGACTTCCTAGATGGTCTCGACAAAGCGGCAGCTATTGCCAAAATGGTCGAGTGGCTT GAAGCAGAAGGTGTTGGTAATGAGAAAGTTACTTACCGTCTTCGTGACTGGCTCTTCAGCCGTCAGCGTTACTGGGGTGA GCCAATCCCAATCATCCACTGGGAAGATGGAACATCAACTGCGGTTCCTGAGAGCGAATTGCCACTAGTTCTTCCAGTTA CTAAGGATATCCGTCCTTCAGGTACTGGTGAGAGCCCACTTGCTAACTTGACAGACTGGTTGGAAGTCACTCGTGAAGAT GGCGTTAAAGGTCGTCGTGAGACCAACACCATGCCACAATGGGCAGGTTCAAGCTGGTACTATCTCCGCTACATCGATCC ACACAACACTGAAAAACTAGCTGACGAGGAACTCCTCAAACAATGGTTGCCAGTTGATATCTATGTCGGTGGTGCAGAGC ATGCCGTGCTTCACCTTCTCTATGCTCGCTTCTGGCACAAGGTTCTTTATGATCTCGGTGTCGTACCTACCAAAGAGCCA TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACAAGCTACCGCGACAGCCGTGGTGCTCTTGTGGCAACTGACAA GGTTGAAAAACGTGATGGCAGCTTCTTCCATGTGGAAACTGGTGAAGAGCTTGAACAAGCACCTGCTAAGATGTCTAAAT CACTTAAGAACGTTGTCAATCCAGATGATGTTGTTGAGCAGTACGGTGCTGACACCCTTCGTGTTTACGAGATGTTCATG GGACCACTCGATGCTTCAATCGCTTGGTCTGAAGAAGGTCTTGAAGGCTCACGTAAGTTCTTGGACCGTGTTTACCGTTT GATCACGACTAAAGAGATCACTGAGGAAAATAGCGGAGCTCTTGACAAGGTTTACAACGAAACTGTTAAGGCAGTTACTG AGCAAGTTGACCAAATGAAATTCAACACAGCTATCGCTCAACTCATGGTCTTTGTCAATGCAGCCAACAAGGAAGACAAA CTCTTTAGCGACTATGCCAAAGGCTTTGTTCAATTGATTGCACCATTCGCACCGCACTTAGGTGAAGAACTCTGGCAAGT CTTGACAGCCTCAGGACAGTCAATCTCTTACGTGCCATGGCCAAGCTATGACGAAAGCAAATTGGTTGAAAACGAAATCG AAATCGTTGTCCAAATCAAAGGTAAGGTCAAAGCTAAACTCGTCGTTGCTAAAGACCTTTCACGCGAAGAATTGCAAGAT CTTGCTCTTGCTAACGAAAAAGTCCAAGCCGAAATCGCAGGCAAAGACATCATCAAAGTCATCGCAGTACCAAACAAACT CGTTAATATTGTGGTGAAATAA Protein sequence : MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWD AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEI PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKAAAIAKMVEWL EAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP FQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGQSISYVPWPSYDESKLVENEIEIVVQIKGKVKAKLVVAKDLSREELQD LALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 0.0 | 98 |
