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Name : merA-2 (SAG2023) Accession : NP_689009.1 Strain : Streptococcus agalactiae 2603V/R Genome accession: NC_004116 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : - Position : 1998880 - 2000520 bp Length : 1641 bp Strand : - Note : identified by match to PFAM protein family HMM PF00070 DNA sequence : ATGAATAAATTTAAGGTAAACATTTCAGGAATGACTTGTACGGGTTGTGAAAAACACGTAGAATCAGCACTTGAAAAGAT AGGTGCTAAAAATATTGAGTCTAGTTATCGTCGTGGTGAAGCAGTATTTGAACTGCCCGATGATATTGAGGTTGAAAGTG CAATAAAGGCGATTGATGAAGCAAATTACCAAGCCGGAGAAATTGAAGAAGTATCATCACTAGAAAACGTGGCGTTAATT AATGAAGACAATTATGACCTTCTTATTATTGGTTCTGGTGCTGCTGCCTTTTCTTCGGCAATTAAAGCTATAGAATACGG TGCAAAAGTTGGAATGATTGAGCGTGGAACGGTTGGGGGAACCTGTGTGAATATTGGCTGTGTTCCGTCAAAAACTCTTC TTAGGGCAGGGGAAATCAATCATTTATCAAAAGACAATCCGTTTATAGGTTTACAAACATCCGCTGGAGAAGTGGATTTA GCTAGTTTAATCACGCAAAAGGATAAATTGGTGAGCGAACTTCGGAATCAAAAATATATGGATTTAATTGATGAATATAA TTTTGATTTAATTAAAGGTGAAGCAAAATTCGTTGATGCTAGTACGGTTGAGGTCAATGGGACAAAGTTATCTGCAAAAC GCTTTTTAATTGCAACAGGTGCATCGCCTTCGTTGCCCCAAATTTCAGGACTTGAAAAAATGGACTATTTAACTAGTACA ACACTTCTTGAGTTAAAGAAAATACCAAAACGATTAACTGTAATTGGTTCAGGATACATTGGAATGGAGCTTGGACAACT ATTTCATCATTTAGGTTCAGAAATAACGCTTATGCAAAGAAGTGAGCGACTTTTAAAGGAGTATGATCCTGAGATTTCAG AGTCAGTTGAAAAAGCGTTAATTGAACAGGGTATAAACCTTGTCAAAGGGGCAACTTTTGAGCGTGTTGAACAAAGTGGA GAGATAAAAAGGGTTTACGTAACAGTAAATGGCAGTAGAGAAGTCATTGAATCAGATCAGTTACTTGTTGCCACTGGAAG AAAACCAAATACGGATTCTTTAAATTTAAGTGCAGCAGGTGTTGAAACTGGAAAAAATAATGAAATCCTGATCAATGATT TTGGTCAAACAAGTAATGAAAAGATTTATGCAGCAGGAGATGTGACTTTAGGACCACAATTTGTATATGTAGCAGCCTAT GAAGGTGGAATTATTACTGATAATGCTATTGGTGGATTAAACAAAAAAATAGATTTATCGGTAGTTCCTGCTGTTACGTT TACGAATCCGACGGTTGCAACGGTTGGTTTAACAGAAGAACAAGCAAAAGAGAAAGGGTATGATGTGAAGACATCTGTAT TACCTTTAGGTGCTGTTCCAAGAGCAATTGTAAACCGTGAAACAACCGGTGTATTTAAACTAGTAGCAGATGCAGAAACA CTAAAAGTATTAGGGGTTCATATTGTATCTGAAAATGCAGGAGATGTCATCTATGCAGCATCATTAGCTGTTAAATTTGG CTTAACGATAGAAGATTTAACAGAAACCCTAGCACCATATTTAACAATGGCTGAAGGGCTAAAATTAGTTGCACTTACGT TCGATAAAGATATTTCGAAATTATCTTGTTGTGCAGGCTAA Protein sequence : MNKFKVNISGMTCTGCEKHVESALEKIGAKNIESSYRRGEAVFELPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALI NEDNYDLLIIGSGAAAFSSAIKAIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFIGLQTSAGEVDL ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGTKLSAKRFLIATGASPSLPQISGLEKMDYLTST TLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSG EIKRVYVTVNGSREVIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGPQFVYVAAY EGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVKTSVLPLGAVPRAIVNRETTGVFKLVADAET LKVLGVHIVSENAGDVIYAASLAVKFGLTIEDLTETLAPYLTMAEGLKLVALTFDKDISKLSCCAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 0.0 | 68 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 0.0 | 68 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 6e-88 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| merA-2 | NP_689009.1 | mercuric reductase | BAC0224 | Protein | 0.0 | 71 |
| merA-2 | NP_689009.1 | mercuric reductase | BAC0651 | Protein | 0.0 | 68 |
