Gene Information

Name : SAG2022 (SAG2022)
Accession : NP_689008.1
Strain : Streptococcus agalactiae 2603V/R
Genome accession: NC_004116
Putative virulence/resistance : Unknown
Product : ISL3 family transposase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG3464
EC number : -
Position : 1997467 - 1998720 bp
Length : 1254 bp
Strand : -
Note : identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain.

DNA sequence :
ATGTCAGACTTATTATCCCTACCAGACATTAAAACAATAGAACCGCCACAAGAAAATGAAACCGATATGATGTTTAAAGT
TGAAGCAGTCGGACCACCTGAACGTTGTCCTGAATGTGGTTTTGACAAGTTGTACAAACACAGTTCAAGAAATCAACTAA
TTATGGATTTGCCCATTCGTTTAAAGCGAGTGGGCTTACATTTGAACCGTAGACGATACAAGTGTCGTGAATGCGGATCT
ACCATATCTGTAGATGAAAAGCGTAGTATGACCAAAAGGCTTTTAAAGTCCATTCAAGAGCAATCCATGTCTAAGACCTT
TGTAGAAGTCGCAGAAAGCGTTGGTGTTGACGAGAAAACCATTAGGAACGTTTTTAAGGACTATGTGGCACTCAAAGAAC
GTGAATACCAGTTTGAAACTCCTAAGTGGCTTGGGATAGACGAGATACATATTATCCGTAGACCTCGGCTTGTATTGACT
AATATTGAACGCAGGACTATTTATGACATCAAGCCTAACCGTAACAAGGAAACAGTCATCCAACGTCTTTCAGAAATCAG
TGACAGGACTTACATTGAGTACGTCACAATGGATATGTGGAAGCCCTACAAAGACGCAGTGAACACTATCCTTCCACAAG
CTAAAGTTGTCGTAGATAAGTTTCATGTAGTTAGAATGGCTAATCAAGCCTTAGATAACGTCAGAAAGTCTTTGAAAGCC
CATATGAGCCAAAAAGAAAGACGTACCCTTATGCGTGAAAGGTTTATCCTTCTAAAGCGTAAACACGATCTAAATGAACG
TGAATCATTCCTCTTAGATACTTGGTTAGGTAATCTTCCTGCTTTAAAAGAAGCCTATGAACTCAAAGAAGAGTTTTACT
GGATATGGGATACTCCTGATCCAGATGAAGGTCATCTTCGTTATAGTCAATGGAGACACCGTTGTATGTCCAGCAACTCT
AAAGACGCATATAAAGACCTCGTGAGAGCCGTAGACAACTGGCATGTTGAAATATTCAACTACTTTGATAAAAGGCTCAC
TAATGCTTATACGGAGTCAATTAACAGCATTATTAGGCAGGTAGAGCGAATGGGTAGAGGTTACTCGTTTGATGCCTTAC
GAGCCAAAATCCTTTTCAATGAGAAGCTCCATAAAAAGCGTAAGCCACGATTTAATTCAAGTGCTTTCAATAAAGCTATG
TTATACGATACTTTCAATTGGTATGAAGTGAATGATCACGACATTACAGACTAG

Protein sequence :
MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKLYKHSSRNQLIMDLPIRLKRVGLHLNRRRYKCRECGS
TISVDEKRSMTKRLLKSIQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRPRLVLT
NIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPQAKVVVDKFHVVRMANQALDNVRKSLKA
HMSQKERRTLMRERFILLKRKHDLNERESFLLDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGHLRYSQWRHRCMSSNS
KDAYKDLVRAVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKRKPRFNSSAFNKAM
LYDTFNWYEVNDHDITD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Pmu_03510 YP_005176249.1 transposase tnpA Not tested ICEPmu1 Protein 9e-93 46
tnpA ACS32044.1 transposase of ISL3 family Not tested AbaR5 Protein 2e-70 42
1_52 CAJ77024.1 Transposase Not tested AbaR1 Protein 1e-70 42
1_386 CAJ77097.1 Transposase Not tested AbaR1 Protein 1e-70 42
tpnA ADI24144.1 transposase Not tested AbaR1 Protein 1e-70 42
tpnA ADZ05772.1 transposase Not tested AbaR11 Protein 1e-70 42
tnpA ACN81032.1 transposase of ISL3 family Not tested AbaR5 Protein 2e-70 42
tnpA AGK36656.1 transposase of ISL3 family Not tested AbaR26 Protein 2e-70 41