Gene Information

Name : azi; div (SAG1449)
Accession : NP_688445.1
Strain : Streptococcus agalactiae 2603V/R
Genome accession: NC_004116
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1462596 - 1464983 bp
Length : 2388 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGATAGCCTTTAATAGTTTATTTTCGTTAGATAAGAAACGTTTAAAAAAACTTCAGCGTACTTTAAATACTATCAATAG
TTTAAAGGGCCAAATGGCAACACTATCAAATGAGGAGTTGCAAGCTAAGACAACTGAATTTAGAAAACGTTTAGTTAATG
GGGAAACACTAGATGATATTTGTGCTGAAGCTTTTGCTGTTGTTAGGGAAGCTGATGAGCGCGTATTAGGTCTATTTCCG
TATGATGTACAGGTAATCGGTGGTCTTGTTCTGCACCAAGGAAATACTGCTGAGATGAAAACTGGTGAAGGAAAAACATT
AACTGCCACTATGCCTTTGTATCTCAATGCTTTAGAAGGGAAGGGGGCAATGTTGCTGACTAATAATTCCTACCTTGCTA
TTCGAGATGCGGAAGAAATGGGAAAAGTATATCGTTTTTTAGGATTGAGTGTCGGTGTGGGAGTTTCTGATAATGAGGAA
GAGGATAGAGATGCTGCGACTAAGCGAGCTGTTTATAGTTCGGATATTGTCTATAGTACAAGTAGTGCACTAGGCTTTGA
TTATTTAATTGATAACCTAGCTTCATCTAAATCTCAAAAATATATGCCCAAGTTACATTATGCTATTGTAGATGAAGCTG
ATGCAGTTCTTCTAGATATGGCCCAGACTCCTTTAGTTATTTCAGGTTCACCTCGAGTACAATCTAATCTCTATAAAATA
GCAGATGAACTAATTCTTAGTTTTGAAGAACAAGTTGATTATTATTTTGACAAAGAGCGTCAGGAAGTGTGGATAAAAAA
CCAGGGTGTTCGTGAAGCTGAGAGATATTTTAGAATCCCTCATTTTTATAAACAGTCTAATCGAGAACTTGTGCGACATT
TGAACTTATCTTTAAAAGCACATAAATTATTTGAACGAGGAAAAGATTATGTGGTTGACGATGGTGAAATCAAGTTGCTA
GATGCGACTAATGGCCGTGTTTTAGAAGGTACTAAACTTCAAGGAGGTGTTCATCAAGCTATTGAGCAAAAAGAGCATCT
TAATGTCACACCAGAGTCTCGAGCAATGGCTTCCATTACCTATCAAAATCTTTTTAGAATGTTTACTAAATTGGCTGGAA
TGACAGGAACTGGAAAAACTGCTGAAAAAGAGTTTATTGAGGTCTATGATATGGAAGTAGTTAGAATTCCAACTAATTCT
CCTGTTAGACGAATTGACTATCCTGATAAGATTTATACAACCTTACCAGAGAAAATCCATGCAACGATTGAATTTGTTAA
ACAGGTTCATGATACAGGACAACCAATCCTACTAGTTGCCGGTTCTGTGAGAATGTCAGAGCTATTCTCAGAATTATTAT
TACTAAGTGGTATCCCTCATAGCCTGTTAAATGCTCAAAGTGCGGTTAAGGAAGCACAGATGATTGCAGAAGCAGGGCAA
AAAGGTGCGGTCACTGTTGCAACGAATATGGCTGGTCGTGGTACAGATATTAAGTTAGGTAAGGGAGTATCAGAATTAGG
TGGTCTTGCAGTTATTGGAACGGAGAGAATGAAGAGTCAAAGAATGGATTTACAATTAAGGGGACGTTCGGGTCGACAAG
GCGATATTGGTTTTAGTCAATTTTTTGTATCATTTGAAGATGATCTAATGATAGAATCAGGTCCTAAATGGGCGCAAGAT
TACTTTAGGAAAAATCGTGACAAAGTTAATCCAGAAAAACCTAAAGCCTTAGGTCAGAGAAGATTTCAGAAGTTATTCCA
GCAAACTCAGGAAGCTAGTGACGGTAAGGGAGAGTCTGCACGTAGTCAAACGATAGAGTTTGATTCGAGTGTACAGCTTC
AGCGAGAGTATGTTTATCGTGAGAGAAATGCTTTGATCAATGGAGAAAGTGGACATTTTAGTCCAAGACAGATTATTGAT
ACAGTGATTTCTTCCTTCATTGCTTATTTAGATGGTGAAGTAGAAAAAGAAGAACTCATTTTTGAAGTAAATCGTTTTAT
ATTTGATAATATGTCTTACAATCTTCAAGGGATTTCTAAAGAGATGTCACTTGAAGAAATTAAAAACTATTTATTCAAAA
TAGCCGATGAGATTCTTCGAGAAAAGCATAATTTGCTTGGTGATAGTTTTGGTGACTTTGAACGTACTGCTGCTTTAAAA
GCGATTGATGAAGCTTGGATTGAAGAAGTAGATTATCTACAACAATTACGTACTGTGGCAACAGCTCGTCAAACGGCACA
GCGTAACCCGGTTTTCGAATATCATAAAGAAGCATATAAATCCTACAATATCATGAAAAAAGAAATTCGTGAACAAACTT
TTAGAAATCTACTTTTGAGTGAAGTATCCTTCAATGAGAATGGAGATCTTCAAATTTATTTTATATAA

Protein sequence :
MIAFNSLFSLDKKRLKKLQRTLNTINSLKGQMATLSNEELQAKTTEFRKRLVNGETLDDICAEAFAVVREADERVLGLFP
YDVQVIGGLVLHQGNTAEMKTGEGKTLTATMPLYLNALEGKGAMLLTNNSYLAIRDAEEMGKVYRFLGLSVGVGVSDNEE
EDRDAATKRAVYSSDIVYSTSSALGFDYLIDNLASSKSQKYMPKLHYAIVDEADAVLLDMAQTPLVISGSPRVQSNLYKI
ADELILSFEEQVDYYFDKERQEVWIKNQGVREAERYFRIPHFYKQSNRELVRHLNLSLKAHKLFERGKDYVVDDGEIKLL
DATNGRVLEGTKLQGGVHQAIEQKEHLNVTPESRAMASITYQNLFRMFTKLAGMTGTGKTAEKEFIEVYDMEVVRIPTNS
PVRRIDYPDKIYTTLPEKIHATIEFVKQVHDTGQPILLVAGSVRMSELFSELLLLSGIPHSLLNAQSAVKEAQMIAEAGQ
KGAVTVATNMAGRGTDIKLGKGVSELGGLAVIGTERMKSQRMDLQLRGRSGRQGDIGFSQFFVSFEDDLMIESGPKWAQD
YFRKNRDKVNPEKPKALGQRRFQKLFQQTQEASDGKGESARSQTIEFDSSVQLQREYVYRERNALINGESGHFSPRQIID
TVISSFIAYLDGEVEKEELIFEVNRFIFDNMSYNLQGISKEMSLEEIKNYLFKIADEILREKHNLLGDSFGDFERTAALK
AIDEAWIEEVDYLQQLRTVATARQTAQRNPVFEYHKEAYKSYNIMKKEIREQTFRNLLLSEVSFNENGDLQIYFI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 0.0 53