Gene Information

Name : SAG1257 (SAG1257)
Accession : NP_688258.1
Strain : Streptococcus agalactiae 2603V/R
Genome accession: NC_004116
Putative virulence/resistance : Resistance
Product : cation transporter E1-E2 family ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1266612 - 1268741 bp
Length : 2130 bp
Strand : -
Note : identified by match to PFAM protein family HMM PF00122

DNA sequence :
ATGTCTAGAGGGAAAGCAAAACAGTCTGAAAAAGAAATGAAAGCCTATCGTGTTCAAGGATTTACTTGTACTAACTGTGC
AGCCATTTTTGAAAATAATGTTAAAGAACTTCCCGGTGTTCAGGATGCGAAAGTAAATTTCGGAGCATCTAAAGTTTATG
TTAAAGGGACGACAACCATTGAAGAATTAGAAAAAGCAGGAGCATTTGAAAATTTAAAAATTCGAGATGAAAAAGAACAA
AGGGTAGGAGGAGAACCTTTTTGGAAGCAGAAAGAAAACATTAAGGTATATATATCAGCTCTTTTACTTGTAGTTAGCTG
GTTCTTAGGAGAGCAGTATGGTGAAGAGCATGTTCTACCGACAATTGGTTATGCAGCGTCCATTTTAATCGGTGGATATT
CGTTATTTATTAAAGGTCTCAAAAATTTAAGAAGATTAAATTTCGATATGAATACGCTTATGACTATTGCCATTATAGGA
GCTGCAATTATTGGTGAATGGGGTGAAGGGGCAACCGTTGTTATCCTATTTGCGATTAGTGAAGCATTAGAGCGTTATTC
AATGGATAAAGCACGTCAATCTATTGAATCTTTAATGGATATTGCCCCAAAAGAAGCGTTAATTCGACGAGGCAATGAAG
AAATGATGATTCATGTTGATGAGATTCAAGTTGGAGACATCATGATAGTTAAGCCCGGTCAAAAGTTAGCAATGGATGGA
ATAGTGGTTAAAGGTACATCGACATTAAATCAGGCTGCGATTACAGGTGAAAGTGTTCCAGTAACGAAAATCACAAATGA
TGAAGTATTTGCAGGAACCTTGAATGAAGAAGGGTTACTTGAGGTTAAAGTAACAAAACGAGTTGAAGATACTACTCTTT
CAAAAATCATTCACTTGGTAGAAGAAGCCCAAGCAGAACGGGCCCCCTCTCAAGCGTTTGTCGATAAATTTGCAAAATAC
TATACACCAGCTATTGTCATACTAGCTCTTTTAATTGCAGTAGTTCCACCATTATTTGGCGGAGACTGGAGCCAATGGAT
TTATCAAGGATTAGCTGTATTAGTGGTTGGTTGTCCTTGTGCCTTAGTAGTCTCAACTCCAGTTGCTGTGGTTACAGCAA
TAGGAAATGCAGCGAAAAATGGTGTATTAATTAAAGGTGGTATCCATTTAGAAGCAGCAGGACACTTAAAAGCGATAGCA
TTTGATAAAACAGGAACATTAACCAAAGGGATTCCAGCTGTAACAGACATTGTGACATATGGTAGAAATGAAAATGAATT
AATAACCATAACATCAGCCATTGAAAAAGGATCGCAGCACCCTCTTGCTTCAGCGATTATGCGAAAAGCAGAAGAAAATG
GATTAAAATTCAATGAAGTAACAGTAGAGGATTTTCAATCCATTACAGGTAAAGGCGTTAAAGCCAAAATAAATAATGAA
ATGTATTATGTGGGAAGTCAAAATCTTTTTGAGGAATTACACGGAAGCATTTCAAGCGATAAAAAAGAAAAAATTGCCGA
TATGCAAACTCAAGGTAAAACGGTGATGGTGTTAGGAACAGAAAAAGAAATTCTTTCGTTTATTGCCGTAGCCGATGAAA
TGAGGGAATCGTCTAAAGAAGTTATCGGCAAGTTGAACAATATGGGAATCGAAACAGTGATGCTAACAGGCGATAACCAA
AGAACGGCAACAGCCATCGGAAAACAAGTTGGTGTTTCGGATATTAAAGCTGACTTACTTCCAGAAGATAAGCTTAATTT
TATTAAAGAACTTCGAGAAAAACATCAAAGTGTGGGGATGGTCGGAGATGGCGTGAATGATGCTCCAGCCCTTGCGGCAT
CTACCGTTGGTGTAGCAATGGGTGGTGCTGGAACTGATACAGCTTTAGAAACGGCTGACATCGCCTTAATGTCTGATGAT
TTGAGTAAATTGCCATATACAATAAAATTAAGCCGTAAGGCTTTAGCAATCATCAAGCAAAACATTACCTTCTCTTTGGC
GATTAAATTAGTGGCATTACTTTTGGTCATGCCCGGTTGGTTAACACTTTGGATAGCGATATTTGCTGATATGGGAGCAA
CTTTACTTGTAACATTAAACAGTTTACGCTTATTGAAAATCAAAGAATAG

Protein sequence :
MSRGKAKQSEKEMKAYRVQGFTCTNCAAIFENNVKELPGVQDAKVNFGASKVYVKGTTTIEELEKAGAFENLKIRDEKEQ
RVGGEPFWKQKENIKVYISALLLVVSWFLGEQYGEEHVLPTIGYAASILIGGYSLFIKGLKNLRRLNFDMNTLMTIAIIG
AAIIGEWGEGATVVILFAISEALERYSMDKARQSIESLMDIAPKEALIRRGNEEMMIHVDEIQVGDIMIVKPGQKLAMDG
IVVKGTSTLNQAAITGESVPVTKITNDEVFAGTLNEEGLLEVKVTKRVEDTTLSKIIHLVEEAQAERAPSQAFVDKFAKY
YTPAIVILALLIAVVPPLFGGDWSQWIYQGLAVLVVGCPCALVVSTPVAVVTAIGNAAKNGVLIKGGIHLEAAGHLKAIA
FDKTGTLTKGIPAVTDIVTYGRNENELITITSAIEKGSQHPLASAIMRKAEENGLKFNEVTVEDFQSITGKGVKAKINNE
MYYVGSQNLFEELHGSISSDKKEKIADMQTQGKTVMVLGTEKEILSFIAVADEMRESSKEVIGKLNNMGIETVMLTGDNQ
RTATAIGKQVGVSDIKADLLPEDKLNFIKELREKHQSVGMVGDGVNDAPALAASTVGVAMGGAGTDTALETADIALMSDD
LSKLPYTIKLSRKALAIIKQNITFSLAIKLVALLLVMPGWLTLWIAIFADMGATLLVTLNSLRLLKIKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 65
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 64
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 64

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAG1257 NP_688258.1 cation transporter E1-E2 family ATPase BAC0298 Protein 2e-115 48
SAG1257 NP_688258.1 cation transporter E1-E2 family ATPase BAC0092 Protein 9e-93 43