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Name : SAG1253 (SAG1253) Accession : NP_688255.1 Strain : Streptococcus agalactiae 2603V/R Genome accession: NC_004116 Putative virulence/resistance : Unknown Product : ISL3 family transposase Function : - COG functional category : L : Replication, recombination and repair COG ID : COG3464 EC number : - Position : 1261820 - 1263127 bp Length : 1308 bp Strand : - Note : identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain. DNA sequence : ATGTCAGACTTATTATCCCTACCAGACATTAAAACAATAGAACCGCCACAAGAAAATGAAACCGATATGATGTTTAAAGT TGAAGCAGTCGGACCACCTGAACGTTGTCCTGAATGTGGTTTTGACAAGTTGTACAAACACAGTTCAAGAAATCAACTAA TTATGGATTTGCCCATTCGTTTAAAGCGAGTGGGCTTACATTTGAACCGTAGACGATACAAGTGTCGTGAATGCGGATCT ACCATATCTGTAGATGAAAAGCGTAGTATGACCAAAAGGCTTTTAAAGTCCATTCAAGAGCAATCCATGTCTAAGACCTT TGTAGAAGTCGCAGAAAGCGTTGGTGTTGACGAGAAAACCATTAGGAACGTTTTTAAGGACTATGTGGCACTCAAAGAAC GTGAATACCAGTTTGAAACTCCTAAGTGGCTTGGGATAGACGAGATACATATTATCCGTAGACCTCGGCTTGTATTGACT AATATTGAACGCAGGACTATTTATGACATCAAGCCTAACCGTAACAAGGAAACAGTCATCCAACGTCTTTCAGAAATCAG TGACAGGACTTACATTGAGTACGTCACAATGGATATGTGGAAGCCCTACAAAGACGCAGTGAACACTATCCTTCCACAAG CTAAAGTTGTCGTAGATAAGTTTCATGTAGTTAGAATGGCTAATCAAGCCTTAGATAACGTCAGAAAGTCTTTGAAAGCC CATATGAGCCAAAAAGAAAGACGTACCCTTATGCGTGAAAGGTTTATCCTTCTAAAGCGTAAACACGATCTAAATGAACG TGAATCATTCCTCTTAGATACTTGGTTAGGTAATCTTCCTGCTTTAAAAGAAGCCTATGAACTCAAAGAAGAGTTTTACT GGATATGGGATACTCCTGATCCAGATGAAGGTCATCTTCGTTATAGTCAATGGAGACACCGTTGTATGTCCAGCAACTCT AAAGACGCATATAAAGACCTCGTGAGAGCCGTAGACAACTGGCATGTTGAAATATTCAACTACTTTGATAAAAGGCTCAC TAATGCTTATACGGAGTCAATTAACAGCATTATTAGGCAGGTAGAGCGAATGGGTAGAGGTTACTCGTTTGATGCCTTAC GAGCCAAAATCCTTTTCAATGAGAAGCTCCATAAAAAGCGTAAGCCACGATTTAATTCAAGTGCTTTCAATAAAGCTATG TTATACGATACTTTCAATTGGTATGAAGTGAATGATCACGACATTACAGACAACTTAGGTGTCGATTTTTCCACACTTAT TAAGAATTTGGAGAAGGGTGATTTATAA Protein sequence : MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKLYKHSSRNQLIMDLPIRLKRVGLHLNRRRYKCRECGS TISVDEKRSMTKRLLKSIQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRPRLVLT NIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPQAKVVVDKFHVVRMANQALDNVRKSLKA HMSQKERRTLMRERFILLKRKHDLNERESFLLDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGHLRYSQWRHRCMSSNS KDAYKDLVRAVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKRKPRFNSSAFNKAM LYDTFNWYEVNDHDITDNLGVDFSTLIKNLEKGDL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| Pmu_03510 | YP_005176249.1 | transposase tnpA | Not tested | ICEPmu1 | Protein | 3e-97 | 46 |
| tpnA | ADZ05772.1 | transposase | Not tested | AbaR11 | Protein | 9e-71 | 41 |
| tnpA | ACN81032.1 | transposase of ISL3 family | Not tested | AbaR5 | Protein | 1e-70 | 41 |
| tnpA | ACS32044.1 | transposase of ISL3 family | Not tested | AbaR5 | Protein | 1e-70 | 41 |
| tnpA | AGK36656.1 | transposase of ISL3 family | Not tested | AbaR26 | Protein | 1e-70 | 41 |
| 1_52 | CAJ77024.1 | Transposase | Not tested | AbaR1 | Protein | 9e-71 | 41 |
| 1_386 | CAJ77097.1 | Transposase | Not tested | AbaR1 | Protein | 9e-71 | 41 |
| tpnA | ADI24144.1 | transposase | Not tested | AbaR1 | Protein | 9e-71 | 41 |
