Gene Information

Name : guaA (tll2418)
Accession : NP_683208.1
Strain : Thermosynechococcus elongatus BP-1
Genome accession: NC_004113
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2530883 - 2532490 bp
Length : 1608 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGACTCACTCCACCCTCCACCAACCGGATACAGCCACTGGCCAAGGCCTGCAACGCCAACTCATTGTCATTCTCGATTT
TGGGTCGCAATACTCGGAACTGATTGCCCGCCGTATTCGTGAGACCCAAGTCTATTCCGAGGTCATTTCCTATCGCACCA
CTGCTGAGCAACTCGCCCAATTGGCACCCAAGGGCATTATTCTCTCCGGTGGCCCCAACTCTGTCTATGACGAAAATGCC
CCCCAATGCGATCCAGAGATTTGGAACCTGGGGATTCCCATTCTTGGGGTGTGCTACGGCATGCAACTGATGGTGCAACA
GTTGGGGGGAACGGTAGAGCGAGCGATCGCCGGCGAGTATGGCAAGGCGGCGCTTTTTATTGATGACCCCACAGATCTGC
TCACCAATGTCGAGCAGGAAACAATTATGTGGATGAGTCATGGCGATAGTGTCACCGAGTTGCCCCCCGGTTTTCGTGTC
TTGGCGCATACCGACAATACGCCAATAGCAGCGATCGCCCATCCCGAGCGGAAACTCTATGGAGTTCAGTTTCACCCAGA
GGTGGTGCATTCTGTGGGGGGCATTGCCCTGATCCGCAACTTTGTCTATCACATTTGCGATTGCGAACCCACTTGGACAA
CTGCTGCCTTTGTTGAAGAGGCCATCCGGGAAGTGCGAGCCAAAGTGGGGGACAAACGGGTCCTCCTTGCCCTGTCGGGG
GGGGTAGATTCATCGACGCTGGCCTTTTTGCTCCACCGTGCCATTGGCGATCAGCTCACCTGTATGTTTATTGACCAAGG
GTTTATGCGCAAAGGGGAGCCCGAGCGACTCCTCAAGCTCTTTCAGGAGCAGTTTCACATCAAGGTGGAGTACGTCAATG
CCCGCGATCGCTTCCTTGCCCAACTGGTGGGGGTCACCGATCCTGAAGAAAAGCGCAAACGCATTGGCCATGAATTTATC
CGCGTTTTCGAAGAAGAATCACAGCGGCTAGGTCCCTTCGACTACTTAGCGCAGGGAACCCTTTATCCCGATGTCATTGA
ATCTGCGAATACCAACATTGACCCCCAAACGGGTGAGCGCGTAGCGGTGAAAATTAAGAGCCACCACAATGTTGGCGGCC
TGCCGGAGAACTTGCGTTTTAAGCTGGTGGAACCCCTACGCAAGCTCTTTAAGGATGAAGTGCGCCAAGTGGGGCGATCC
CTGGGGCTACCCGAAGAAATTGTGCAGCGGCATCCCTTTCCCGGTCCCGGTTTAGCAATTCGGATTCTGGGGGAAGTGAC
CCCGGAACGTCTAGAGATTCTACGGGATGCGGATCTGATTGTGCGGCAGGAAATTAACCGCGCCCAGATGTATCACGAGC
TTTGGCAAGCCTTTGCGGTACTACTGCCGATTCGCACCGTGGGGGTCATGGGGGATCAGCGCACCTACGCTTATCCAGTG
GTGCTGCGATTTGTCACCAGCGAAGATGGCATGACCGCGGACTGGGCACGGGTTCCCTACGACCTTCTGGAGCGAATTTC
CAACCGCATTGTCAACGAAGTGCCGGGGGTGAATCGGGTGGTCTATGACATTACCTCCAAGCCGCCGGGAACCATTGAGT
GGGAGTAA

Protein sequence :
MTHSTLHQPDTATGQGLQRQLIVILDFGSQYSELIARRIRETQVYSEVISYRTTAEQLAQLAPKGIILSGGPNSVYDENA
PQCDPEIWNLGIPILGVCYGMQLMVQQLGGTVERAIAGEYGKAALFIDDPTDLLTNVEQETIMWMSHGDSVTELPPGFRV
LAHTDNTPIAAIAHPERKLYGVQFHPEVVHSVGGIALIRNFVYHICDCEPTWTTAAFVEEAIREVRAKVGDKRVLLALSG
GVDSSTLAFLLHRAIGDQLTCMFIDQGFMRKGEPERLLKLFQEQFHIKVEYVNARDRFLAQLVGVTDPEEKRKRIGHEFI
RVFEEESQRLGPFDYLAQGTLYPDVIESANTNIDPQTGERVAVKIKSHHNVGGLPENLRFKLVEPLRKLFKDEVRQVGRS
LGLPEEIVQRHPFPGPGLAIRILGEVTPERLEILRDADLIVRQEINRAQMYHELWQAFAVLLPIRTVGVMGDQRTYAYPV
VLRFVTSEDGMTADWARVPYDLLERISNRIVNEVPGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-143 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-143 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-142 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-134 53