Gene Information

Name : leuS (tll2098)
Accession : NP_682888.1
Strain : Thermosynechococcus elongatus BP-1
Genome accession: NC_004113
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2179495 - 2182068 bp
Length : 2574 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGACGATCGCTACGACCCCCAAGTGATTGAGGCCAAGTGGCAACAGGAATGGGCTGCACGCCAACTGGATCGCACCGA
CACTGATCCGCAAAAACCCAAATTCTATGCCCTCTCAATGTTCCCCTACCCCTCAGGGAATCTGCACATGGGGCACGTCC
GCAACTATACGATTACCGATGTCATTGCCCGCTGTCGGCGGATGCAGGGCTATCGCGTTCTCCACCCCATGGGCTGGGAT
GCCTTTGGCCTGCCGGCGGAAAATGCTGCCATTGAACGGGGAATTCATCCCCGCGTCTGGACACAACAGAATATTGGCCA
AATGCGCCAAGAACTGCAACGTCTTGGCCTCTCCTACGATTGGGAACGGGAGGTGACCACCTGTCACCCTGACTACTACC
GCTGGACACAATGGCTGTTTTTGGAATTCTTTGAGGCGGGCTTGGCCTACCAGAAAGAGGCCGCAGTGAACTGGGATCCT
GTGGATCAAACCGTTTTGGCCAATGAGCAGGTGGACAGTGAGGGACGGTCCTGGCGATCGGGGGCCCTAGTGGAACGGCG
ACTGCTTAAGCAATGGTTCCTGAAAATTACCGCCTATGCCGAGGAACTGTTGAATGACTTGGAACAACTGACGGGCTGGC
CAGAGCGGGTGAAATTAATGCAGGCCAACTGGATCGGTCAGTCCAGGGGTGCCTATTTGGAATTCCCAATTGTTGGCAGT
GATGAGAAAATTGGCGTTTTTACCACCCGTCCCGATACGGTCTATGGCGTCACATACGTGGTGCTGGCCCCAGAACATCC
CCTGACGCTGAAGGTGACCACGAGCCGCCGCCGCAAAACTGTTGAAGCCTTTATTGCCAGTGTGCAACAGGAAAGTGAAC
TGGAACGTACGGCGGGCGATCGCCCCAAACGGGGGGTGGCCACCGGCGGCAAAGCCCTGAACCCCTTTACCGGCGAAGAA
ATCCCGATTTGGATTGCTAATTATGTCCTCTACGAATACGGGACGGGTGCCGTGATGGGTGTACCTGCCCACGATGAGCG
GGATTTTCAATTTGCCAAAGCCCACAGGCTCCCCATCCGCCAAGTGATCATCCCCCCAGACGGCAAAGCCAGTACCCGCC
TCAGGGCCGCCTATACGGAGCCGGGGAAACTGATCAATAGTGGCCAATTTGATGGGATGGACTCCACTGCAGCTAAAGTA
GCCATTACCGAATACGCAACGGCTCAAGGTTGGGGACGGGAGCACGTGCAGTATCGCCTACGGGATTGGCTCATTTCCCG
CCAACGCTATTGGGGAGTCCCCATTCCCATCATTCACTGTCCACAGTGTGGGCCAGTGCCGGTGCCGCGCTCAGAGTTAC
CGGTGCTCCTCCCTGAAGAGGTGGAGTTTACCGGTCGTGGGCCTTCTCCCTTGGCAAAGCTGGCTGCATGGCGCGATGTC
CCCTGCCCGAAGTGTGGTGGGCCAGCTCAGCGGGAAACAGATACTATGGATACGTTCATTGACTCCTCTTGGTACTACTT
CCGCTACGCTGATGCCCGCAACAGTGAAGCCCCCTTTGACCCGGCAGCCATCAAGGACTGGTTACCGGTGGATCAGTACG
TGGGGGGAATTGAGCACGCCATTCTTCATTTGCTCTACTCGCGCTTTTTTACCAAAGTCTTGCGCGATCGCCAGCTCGTG
CATGTGAGTGAACCCTTTCAGCGCCTGCTCACCCAAGGCATGGTTCAAGGGCGCACCTACAAAAATCCACGCACTGGTAA
ATACGTCATTCCCAGTCGCATTGCCGATCTCAACCAACCCACTGACCCCGACACAGGGGAAGCCCTAGAGGTGGTCTATG
AGAAAATGTCCAAGTCGAAATACAACGGCGTTGCCCCCGGCGATGTCATCCAACAGTACGGTGCCGACACCGCGCGGATG
TTTATTCTCTTCAAAGCGCCCCCCGAAAAAGACCTGGAATGGGACGATGCTGATGTTGAAGGGCAGTTTCGCTTCCTCAA
CCGCGTCTGGCGACTGGTACAAACGTTCAAAGCCAAGGGGGGTCGGCTGGGACAACCGCTGCCCGCAACCCTCACTAAAG
CCGAAAAAGATCTGCGCCGGGCCATTCACACAGCCATTAAAGAAATCAGCGAAGACATTGAAGGTGACTATCAACTGAAT
ACGGCCGTTGCTGAACTCATGAAACTCAGTAACGCCCTCAGCAGTGCCGACTGCTACACCTCTGGGGTCTATAGCGAAGG
CATCCAAACCCTACTCACCCTCCTTGCCCCCTTTGCCCCCCACATCAGCGAAGAACTCTGGCATCAACTGGGGGGCACTG
ATTCAATTCACCGCCAGCCCTGGCCAAAAGCAGACCCCACTGCCCTGGTTGCCGATGAAATCACCCTTGTCATTCAGGTC
ATGGGTAAAACCCGTGGCGCGATCCAAGTGCCAGCCACTGCCAGCCAAGCCGAACTGGAGGAAGCTGCCCAGCACTCAGA
GATTGGCCAACGCTATCTCGCGGGTAAAACCATTAAAAAAATCATTGTTGTGCCGGGCAAGTTGGTGAACTTTGTCCTAG
AGTCCTCAAGGTAA

Protein sequence :
MDDRYDPQVIEAKWQQEWAARQLDRTDTDPQKPKFYALSMFPYPSGNLHMGHVRNYTITDVIARCRRMQGYRVLHPMGWD
AFGLPAENAAIERGIHPRVWTQQNIGQMRQELQRLGLSYDWEREVTTCHPDYYRWTQWLFLEFFEAGLAYQKEAAVNWDP
VDQTVLANEQVDSEGRSWRSGALVERRLLKQWFLKITAYAEELLNDLEQLTGWPERVKLMQANWIGQSRGAYLEFPIVGS
DEKIGVFTTRPDTVYGVTYVVLAPEHPLTLKVTTSRRRKTVEAFIASVQQESELERTAGDRPKRGVATGGKALNPFTGEE
IPIWIANYVLYEYGTGAVMGVPAHDERDFQFAKAHRLPIRQVIIPPDGKASTRLRAAYTEPGKLINSGQFDGMDSTAAKV
AITEYATAQGWGREHVQYRLRDWLISRQRYWGVPIPIIHCPQCGPVPVPRSELPVLLPEEVEFTGRGPSPLAKLAAWRDV
PCPKCGGPAQRETDTMDTFIDSSWYYFRYADARNSEAPFDPAAIKDWLPVDQYVGGIEHAILHLLYSRFFTKVLRDRQLV
HVSEPFQRLLTQGMVQGRTYKNPRTGKYVIPSRIADLNQPTDPDTGEALEVVYEKMSKSKYNGVAPGDVIQQYGADTARM
FILFKAPPEKDLEWDDADVEGQFRFLNRVWRLVQTFKAKGGRLGQPLPATLTKAEKDLRRAIHTAIKEISEDIEGDYQLN
TAVAELMKLSNALSSADCYTSGVYSEGIQTLLTLLAPFAPHISEELWHQLGGTDSIHRQPWPKADPTALVADEITLVIQV
MGKTRGAIQVPATASQAELEEAAQHSEIGQRYLAGKTIKKIIVVPGKLVNFVLESSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-168 46