Gene Information

Name : smpB (tll1927)
Accession : NP_682717.1
Strain : Thermosynechococcus elongatus BP-1
Genome accession: NC_004113
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2018261 - 2018719 bp
Length : 459 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGGTGATAGCATCAAAGTCCTGAGTGAGAATCGCCAAGCGCGCTTCCAATATGAAATTCTGGAAACCTATGAATGTGG
TCTTGTGTTGCTGGGCACTGAGGTGAAGTCTATTCGCGCTGGCAAGGTCAATTTACGGGATGGTTTTGCCCGCATCCGCA
ATGGTGAAGCGTGGTTGATGAATGTCCACATTTCGCCCCACGAAAGTACCAACCCATCCTATAACCATGACCCCTTGCGC
GATCGCAAGCTCCTTCTCCACAAGCAGGAGATCCGTAAGCTGGTGGGCAAAGTTGAACAAAAGGGGCTGACCCTTGTGCC
CCTAAAGCTCTACCTAAAAAATGGTCGGGTCAAGGTCTCCCTCGGCCTTGCCCGTGGTAAGAAACTCCACGACAAGCGCC
AAGACCTCAAGCAGCGGCAGGACAAGCGGGAAATGGAGCGGGCAATGAAGCAGCGCTAA

Protein sequence :
MGDSIKVLSENRQARFQYEILETYECGLVLLGTEVKSIRAGKVNLRDGFARIRNGEAWLMNVHISPHESTNPSYNHDPLR
DRKLLLHKQEIRKLVGKVEQKGLTLVPLKLYLKNGRVKVSLGLARGKKLHDKRQDLKQRQDKREMERAMKQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-34 58
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-32 52
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-25 42