Gene Information

Name : clpB (y0914)
Accession : NP_668245.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Unknown
Product : protein disaggregation chaperone
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1021277 - 1023871 bp
Length : 2595 bp
Strand : +
Note : residues 8 to 864 of 864 are 86.69 pct identical to residues 1 to 857 of 857 from E. coli K12 : B2592; residues 4 to 864 of 864 are 86.64 pct identical to residues 1 to 861 of 861 from GenPept : >gb|AAG57705.1|AE005489_4 (AE005489) heat shock protein [Esc

DNA sequence :
TTGACCAATATTGGAGGTGTTATGCGTCTGGATCGTCTTACCAGTAAATTCCAGCTTGCCCTCGCCGATGCCCAGTCTTT
AGCTCTTGGGCGCGACAACCAGTTTATTGAACCGTTACATTTGATGAGCGCACTGCTTAATCAGGATGGGGGGACGGTTC
GCCCTTTATTGACCTCGGCAGGGATTAATGTTGCACGTTTACGTAGCGACATTGAGCAAGCTTTAGGTCGTCTTCCTCAA
GTTGAAGGCACCGGCGGTGATGTTCAACCATCAAACGAGCTGGTTCGTGTATTAAATCTTTGCGACAAATTAGCGCAGAA
ACGTTCGGATAAGTTTATCTCTTCCGAGCTGTTCGTCCTGGCCGTACTTGAAGATCGTGGCACGTTAACTGACATGTTAA
AGGCTGCAGGTGCAACCGTCGCTATAATAGATAAGGCAATTGAAACCATGCGTGGTGGTGACAAAGTCGATGATCAGGGT
GCTGAAGATCAGCGCCAGGCGTTGAAAAAATTCACTATCGACCTGACTGAGCGTGCCGAGCAAGGCAAACTCGATCCGGT
TATTGGCCGTGATGAAGAAATTCGCCGTACTATTCAGGTATTACAACGTCGAACCAAAAATAACCCAGTGTTGATTGGTG
AGCCTGGGGTGGGTAAAACCGCTATTGTGGAAGGTTTGGCGCAACGCATTGTGAACGGCGAAGTGCCAGAAGGCTTGAAG
CATAAGCGTGTACTCTCATTAGATATGGGGTCGCTGATTGCCGGTGCCAAATATCGTGGTGAATTTGAAGAGCGTTTGAA
AGGCGTACTGAACGACTTATCAAAACAAGAAGGCAGTGTGATCTTGTTTATTGATGAGTTGCATACCATGGTCGGTGCCG
GTAAAGGCGATGGGGCGATGGATGCCGGTAACATGCTGAAACCTGCATTAGCGCGAGGTGAGTTACATTGTGTGGGGGCC
ACTACCCTCGATGAATACCGTCAATATATAGAGAAAGATGCTGCGCTCGAGCGGCGTTTCCAAAAAGTGTATGTTGCGGA
ACCAACGGTAGAAGACACTATCGCTATTTTACGTGGGCTGAAAGAGCGCTACGAACTGCACCATCACGTGCAGATCACTG
ACCCAGCTATTGTGGCAGCCGCAACATTGTCACACCGGTATATTTCTGATCGTCAGTTACCGGATAAAGCTATCGACCTC
ATTGATGAGGCAGGTTCCAGCATCCGTATGCAAATGGATTCAAAACCCGAATCATTGGATCGTCTAGAGCGCCGGATTAT
TCAGCTTAAACTGGAACAGCAGGCCCTAAAAAAAGAGTCAGATGACGCCAGTAAAAAACGGTTGGAAATGCTCAATACTG
AGTTAGAGCAAAAAGAGCGTGAATATTCTGAACTGGAAGAAGAGTGGAAAGCAGAAAAAGCTTCACTCACCGGGACTCAG
AATATCAAGACGGAGTTGGAACAAGCTAAAATCACCTTAGAACAAGCTCGTCGAGTAGGTGATCTGGCTCGGATGTCAGA
ACTTCAGTACGGTACAATCCCTGAGCTGGAAAAACAGCTGGCGGCGGCAACCGCGCTAGAAGGGAAAACCATGAAGTTGC
TGCGTAACCGTGTCACAGAAATCGAAGTTGCTGAAGTCCTGGCTCGCTGGACCGGTATCCCGGTATCTCGCATGTTGGAA
AGTGAGCGGGATAAGCTGCTACGTATGGAACAGGACTTGCATCAACGAGTCATTGGGCAAGATGAAGCTGTTGAAGCCGT
CTCCAACGCTATCCGTCGGAGTCGCGCAGGGTTGTCTGATCCAAACCGACCAATTGGTTCGTTCTTATTCTTAGGGCCAA
CGGGGGTTGGTAAAACTGAATTGTGTAAAGCGTTGGCAACGTTCTTGTTCGACAGTGACGATGCCATGGTGCGAATCGAC
ATGTCCGAGTTTATGGAGAAACATTCCGTATCGCGGTTGGTCGGTGCACCTCCTGGCTATGTTGGGTATGAAGAAGGTGG
CTATCTGACGGAAGCGGTTCGTCGTCGTCCTTATTCTGTGATTTTGCTGGATGAAGTTGAAAAAGCACATCCAGATGTTT
TCAACATATTGTTACAGGTATTGGATGATGGTCGTTTGACCGACGGGCAGGGGAGAACTGTCGACTTTCGTAACACGGTA
GTCATTATGACCTCTAACCTTGGTTCAGATTTGATTCAGGAACATTTCGGCCAAATGAATTACAGCGAAATGAAGACAGT
GGTTATGGATGTTGTTAGTCACCACTTCCGTCCTGAATTTATTAACCGTATAGATGAGGTTGTTGTCTTCCACCCACTTG
GTCGGGCGCACTTGGCTTCTATTGCCAACATTCAACTGGAGCGTTTGTATAAACGTCTGGAAGAACGTGGCTATGAAGTG
AAGATTACTCAGCCTGCATTGGAATTCTTGGGTGAAGCTGGCTTCGACCCTGTTTATGGGGCGCGGCCATTAAAACGTGC
AATTCAGCAGGAAATTGAGAACCCGCTGGCACAGCAGATACTTTCTGGCAAACTAATACCGGGAATCCCCGTGACTTTAG
ATGTTGAAAATGGGCATATTATTGCTAAGCAGTAA

Protein sequence :
MTNIGGVMRLDRLTSKFQLALADAQSLALGRDNQFIEPLHLMSALLNQDGGTVRPLLTSAGINVARLRSDIEQALGRLPQ
VEGTGGDVQPSNELVRVLNLCDKLAQKRSDKFISSELFVLAVLEDRGTLTDMLKAAGATVAIIDKAIETMRGGDKVDDQG
AEDQRQALKKFTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLK
HKRVLSLDMGSLIAGAKYRGEFEERLKGVLNDLSKQEGSVILFIDELHTMVGAGKGDGAMDAGNMLKPALARGELHCVGA
TTLDEYRQYIEKDAALERRFQKVYVAEPTVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDL
IDEAGSSIRMQMDSKPESLDRLERRIIQLKLEQQALKKESDDASKKRLEMLNTELEQKEREYSELEEEWKAEKASLTGTQ
NIKTELEQAKITLEQARRVGDLARMSELQYGTIPELEKQLAAATALEGKTMKLLRNRVTEIEVAEVLARWTGIPVSRMLE
SERDKLLRMEQDLHQRVIGQDEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALATFLFDSDDAMVRID
MSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTV
VIMTSNLGSDLIQEHFGQMNYSEMKTVVMDVVSHHFRPEFINRIDEVVVFHPLGRAHLASIANIQLERLYKRLEERGYEV
KITQPALEFLGEAGFDPVYGARPLKRAIQQEIENPLAQQILSGKLIPGIPVTLDVENGHIIAKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-103 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-99 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-99 41