Gene Information

Name : y0850 (y0850)
Accession : NP_668184.2
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : outer membrane receptor
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG4771
EC number : -
Position : 950277 - 952373 bp
Length : 2097 bp
Strand : +
Note : probably for iron transport; similar to receptors for iron transport; residues 48 to 731 of 731 are 56.26 pct identical to residues 17 to 696 of 696 from GenPept : >gb|AAG55732.1|AE005310_8 (AE005310) receptor [Escherichia coli O157:H7 EDL933]

DNA sequence :
ATGTCAAATAAAACAATAGCGTTCGCGTTAGTAGTGGCATCATCAGCCCCTGTTATCGCAGCAGATAATGACAATATTAT
GGTTGTTACCGCATCGGGATATGAACAGAAGATCAGAGAGGCTGCGGCAAGCATCTCGGTCATTAGCCAAAATGAATTAC
GTCAGCGCAATTACAACGATTTGGCGCAAGCGCTGAGTGATGTTGAAGGTGTTGACGTCAATAGCAGCACGGGGAAAACC
GGGGGGCTGGATATCAGTATTCGTGGTATGCCCAGCGCTTATACCCTGATATTGGTGGATGGGATCCGGCAAAATGGCAC
TTCCGATGTAACGCCAAATGGCTTTGGTGCCATGAATACCAGCTTTATGCCCCCGCTATCGGCCATTGAGCGCATCGAAG
TGATCAGGGGACCGATGTCAACGCTCTACGGTTCTGATGCTATCGGTGGTGTTGTTAATATCATCACAAAAAAGATCACC
AAAGCGTGGGCCAGCTCAGCAACGCTTGAACACACCTTCCAGGAAAATACGGCTTTTGGTGACAGTTCAAAGTTCTCTTT
TTACTCCAGTGGGCCAGCGGTTGAAGATCAACTGGGGCTGTCGTTACGTGGCACGATTTTCCGGCGCGATGCCTCTCGCG
TTGAATCCTCCAATACGGGAGTAGAATTAAGCCGTCGTGGTCCCAATCCAGTAAAAGCAGACAACTATAATCTCGGTGGC
AAACTATTTTGGCAATTGAATACCCAAAGCACCTTGTGGTTGGATGGTGATATTGCTAACCAAAAATATGATAACAGTGC
CAACCAACTAGGTACCATTGGTGCACGAGGCGGTTACGAAGATACTCTGCGTTATCAACGCCGTAAAATAACCTTGGGCA
ACGATAATCGTTTGGACTTTGGTACCTGGAATTCGAGCTTATCTTATAACCAAACTGAAAATATTGGCCGCTTAATCACC
AATGCATCCGTGCCCCAAGGCTCTGGGTTGGCAGGTGAAAAACGTCTGTTGAAAAATACCAATATCATCCTTGATAGCAA
GCTGGTCGCCCCGCTGGGTGATAACCACATGGTGACCCTTGGCGGTCAATATTGGAATGCCATCATGAAAGACGGCATCG
TACTGGCAAATAATGGCGATGAGTTTGCACAAGATGCCTGGTCATTATTCAGCGAAGATGAATGGCGTCTGCTGGACTCA
CTGGCATTAACCTATGGCGCACGTTATGAATATCAAACTACGTTTGGCGGCCATATTAGCCCACGAGCCTATCTGGTGTG
GGACGCACAGGATAACTGGACGGTGAAAGGGGGTGTCAGCACGGGGTATAAAACCCCCACTCTAGCCCAGTTGCATAATG
GGATTAGCGGTGTCACAGGCCAAGGCACCATCACGACGATTGGTAACCCTAAGCTTGAACCAGAGAGTAGTGTCAACACC
GAGGTCGGTGTCTATTATGAAAACGAAACGGGATTTGGCGCTAATGTGACGCTGTTCCACAACCGCTTCAGGAACAAAAT
CAACAGCGTTTCGATTGATAATACCACCAGCACCTACACCAACGTCGGTAAAGCGATCACGCAGGGTATTGAGGTCGCAT
CCACCATACCACTCTGGTCTGACGATTGGATGCTGGGAATAAATTACACCTTTACCGATAGTGAACAGAAAGATGGCAAC
AATAAAGGGGCTCGCCTGACGAATACACCGAAAAATATGGTTAATGCCCGCCTGAACTGGAATATCAACGAGCAGTTGTC
CACTTGGTTGAAAGCGGAGTATCGCAGTAAAACGGCACGTTTTACCCAAAATTACGCGAATTTGTCTGCGGCAAACAAAG
TGGTTTACAACAATTTAGGCTCAGAGTTTAAACCTTTTAGCGTACTTAATTTGGGGGTGGCCTATAAGGTCACTAAGGAT
GTGACACTGAATGGTGCAGTCAATAACCTGTTGGATAAAGATTTTACTCGCACCCACATTTTTGCTGTGGGGAACGGCAC
CACTACTGCGGGTGATTACTTCACCTCGTCTCAAAGCACTGCCGGTTATGTTGTACCTGGCCGTAATTACTGGGTATCCG
TGAATGTTAATTTCTAG

Protein sequence :
MSNKTIAFALVVASSAPVIAADNDNIMVVTASGYEQKIREAAASISVISQNELRQRNYNDLAQALSDVEGVDVNSSTGKT
GGLDISIRGMPSAYTLILVDGIRQNGTSDVTPNGFGAMNTSFMPPLSAIERIEVIRGPMSTLYGSDAIGGVVNIITKKIT
KAWASSATLEHTFQENTAFGDSSKFSFYSSGPAVEDQLGLSLRGTIFRRDASRVESSNTGVELSRRGPNPVKADNYNLGG
KLFWQLNTQSTLWLDGDIANQKYDNSANQLGTIGARGGYEDTLRYQRRKITLGNDNRLDFGTWNSSLSYNQTENIGRLIT
NASVPQGSGLAGEKRLLKNTNIILDSKLVAPLGDNHMVTLGGQYWNAIMKDGIVLANNGDEFAQDAWSLFSEDEWRLLDS
LALTYGARYEYQTTFGGHISPRAYLVWDAQDNWTVKGGVSTGYKTPTLAQLHNGISGVTGQGTITTIGNPKLEPESSVNT
EVGVYYENETGFGANVTLFHNRFRNKINSVSIDNTTSTYTNVGKAITQGIEVASTIPLWSDDWMLGINYTFTDSEQKDGN
NKGARLTNTPKNMVNARLNWNINEQLSTWLKAEYRSKTARFTQNYANLSAANKVVYNNLGSEFKPFSVLNLGVAYKVTKD
VTLNGAVNNLLDKDFTRTHIFAVGNGTTTAGDYFTSSQSTAGYVVPGRNYWVSVNVNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
r4 AAC61730.1 exogenous ferric siderophore receptor R4 Not tested PAI I CFT073 Protein 1e-175 57
iha AAF36432.2 adhesin Virulence TAI Protein 8e-177 56
Z1178 NP_286713.1 bifunctional enterobactin receptor/adhesin protein Virulence TAI Protein 1e-176 56
Z1617 NP_287121.1 bifunctional enterobactin receptor/adhesin protein Not tested TAI Protein 1e-176 56
c3610 NP_755485.1 bifunctional enterobactin receptor/adhesin protein Not tested PAI I CFT073 Protein 8e-177 56
ECUMN_3356 YP_002414032.1 bifunctional enterobactin receptor/adhesin protein Virulence Not named Protein 8e-177 56
unnamed CAC39288.1 hypothetical protein Not tested LPA Protein 2e-176 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
y0850 NP_668184.2 outer membrane receptor VFG1731 Protein 3e-177 56