Gene Information

Name : y0512 (y0512)
Accession : NP_667850.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : response regulator/transcription activator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 581872 - 582504 bp
Length : 633 bp
Strand : -
Note : residues 4 to 208 of 210 are 54.14 pct identical to residues 5 to 209 of 212 from GenPept : >emb|CAC08853.1| (AX023463) unnamed protein product [Salmonella sp.]

DNA sequence : 
ATGAATACTAAATTATTGATTGTCGACGATCATGAACTCATTATTCATGGCATCAAGAATATGCTGGCCGCCTATCCGCG
CTACCTGATTGTAGGCCAAGCGGATAATGGACTTGAAGTGTATAACTTGTGCCGCCAAACTGAACCTGACATGGTCATTC
TGGATTTAGGATTACCCGGTATGGATGGCCTTGATGTTATCATTCAGTTGCTTCGCCGTTGGCCAGCCCTGAAGATCCTG
ACGTTAACCGCCCGCAATGAAGAACACTATGCCAGCAGAACATTCAACAGTGGAGCCTTAGGTTATGTGCTGAAGAAAAG
TCCCCAGCAAATCCTGATGGCAGCCATTCAAACCGTCGCAATAGGTAAACGTTATATTGACCCCGCCCTTGATGCCTCTA
TGGTAATAAAACTGACCCAAGGATCCGATAATACGCCCCCGGTTCTGACACCTCGCGAGCGGCAGATATTAAAACTTATC
ACCGAGGGATCGTGTAATCGAGTTATTGCTGCTCAACTTTCTATCAGCCAAAAAACCGTCGAAACACATCGGCTGAATAT
GATGAAAAAATTGGATGTACATAAAGTCGCAGAACTTATTCACTGGTCATACCGATTAGGCTTGAATGTCTAA

Protein sequence : 
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPGMDGLDVIIQLLRRWPALKIL
TLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVAIGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLI
TEGSCNRVIAAQLSISQKTVETHRLNMMKKLDVHKVAELIHWSYRLGLNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0255 YP_002345335.1 two-component response regulator Not tested Not named Protein 7e-89 100
ssrB NP_456137.1 putative two-component response regulator Virulence SPI-2 Protein 5e-41 56
ssrB NP_805062.1 two-component response regulator Virulence SPI-2 Protein 5e-41 56
ssrB NP_460356.1 transcriptional activator Virulence SPI-2 Protein 5e-41 56
ssrB YP_216399.1 secretion system transcriptonal activator Virulence SPI-2 Protein 6e-41 56
ssrB CAB09344.1 SsrB Virulence SPI-2 Protein 1e-35 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
y0512 NP_667850.1 response regulator/transcription activator VFG0492 Protein 2e-41 56
y0512 NP_667850.1 response regulator/transcription activator VFG2440 Protein 1e-25 41