Gene Information

Name : actP (y0508)
Accession : NP_667846.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Resistance
Product : acetate permease
Function : -
COG functional category : R : General function prediction only
COG ID : COG4147
EC number : -
Position : 575545 - 577200 bp
Length : 1656 bp
Strand : -
Note : member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake

DNA sequence :
ATGAAGATCCGCCATTGGTCTGCACTTTCTTTATTCGTTTTGCCTGCGCTGGCACAGGCGGAAGCACTTACCGGCGAGGT
CCATCGCCAACCCCTTAATATTCAGGCGATCGTCATGTTTTTGCTGTTTGTTGGCGGAACCTTGTATATCACCTATTGGG
CATCAAAACGTACTCGCTCCCGGCAAGATTATTACACGGCTGGCGGGCGAATTACTGGCTTTCAAAATGGTTTAGCCATC
GCTGGGGATTATATGTCCGCAGCATCATTCCTCGGTATTTCAGCCTTGGTTTATGCTTCCGGTTACGACGGTTTAATTTA
CTCCATCGGCTTCTTAATCGGCTGGCCCATTATTCTATTTTTAATTGCTGAACGCCTGCGTAATTTGGGCCGTTATACCT
TTGCCGATGTTGCCTCTTACCGCTTGCAACAAAGACCCATACGCACATTATCAGCCTGTGGTTCGTTAGTCGTTGTCGCC
CTGTATTTGATCGCTCAGATGGTGGGGGCGGGTAAACTCATTCAACTTTTATTTGGTTTGAACTACCACGTCGCTGTCGT
ATTGGTTGGTATCCTGATGGTGCTGTACGTCCTGTTCGGCGGTATGTTAGCAACCACTTGGGTACAGATAATCAAAGCGG
TCATGCTACTGTCTGGTGCCACATTTATGGCTATTATGGTCATGAAGTCAGTTAATTTTAACTTCAATACATTATTCAGT
GAGGCGGTTAAGGTTCATCCCAAAGGCCTCAGCATCATGAGCCCAGGAGGGTTGGTATCTGACCCGATATCAGCGTTATC
TCTTGGGTTAGCCCTCATGTTTGGCACTGCTGGCTTACCTCATATCCTGATGCGCTTCTTTACCGTAAGCGATGCCAAAG
AAGCACGTAAAAGCGTGTTCTATGCCACAGGTTTTATCGGCTACTTCTACATATTGACCTTTATTATTGGATTCGGCGCG
ATCTTACTCGTCGGTCCAAACCAGACATTTAAAGATGCGGCTGGCGCATTACTGGGTGGTAACAATATGGCTGCGGTCCA
TTTGGCTAATGCTGTCGGGGGGAGCTTCTTCTTAGGCTTTATCTCAGCGGTTGCCTTCGCAACCATTTTGGCTGTAGTGG
CTGGCTTGACATTAGCCGGTGCATCGGCGGTATCTCATGATCTCTATGCCAGCGTCATTAAGAAAGGCAAAGCCAATGAA
CGCGATGAATTGAGAGTCTCCAAAATTACAGTAATCATCTTAGGTATTGTCGCTATCGGTTTGGGGATTTTGTTTGAAAA
CCAGAATATTGCCTTTATGGTCGGGTTGGCATTCTCCATTGCGGCCAGTTGTAACTTCCCAATTATTATCATCTCAATGT
ATTGGGATAAACTGACAACCCGTGGAGCAATGATCGGTGGGTGGCTCGGGTTATCAACGGCAGTGATCCTGATGATTTTA
GGCCCTACGATCTGGGTAACAATCCTTGGTCATGAAAAGCCAATCTATCCGTATGAGTACCCTGCATTGTTTTCAATGAT
AGCGGCGTTCGTCGGTACCTGGTTCTTCTCAATCACGGATAACTCAGAAACCGGCAAACAGGAACGGTTACTATTCAAAT
CACAGTTTGTCCGTTCACAAACCGGCTTGGGGGCATCTAAAGGCGGCGCTCACTGA

Protein sequence :
MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRSRQDYYTAGGRITGFQNGLAI
AGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVA
LYLIAQMVGAGKLIQLLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFS
EAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGA
ILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANE
RDELRVSKITVIILGIVAIGLGILFENQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMIL
GPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQTGLGASKGGAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01502.1 putative amino acid transport protein Not tested PAGI-1 Protein 2e-125 57
cur_1523 YP_001800917.1 transporter Not tested Not named Protein 1e-75 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
actP NP_667846.1 acetate permease BAC0564 Protein 0.0 83
actP NP_667846.1 acetate permease BAC0570 Protein 3e-139 63