Gene Information

Name : thiC (y0491)
Accession : NP_667829.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 553068 - 555113 bp
Length : 2046 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTAATAATACAACGTCATTACCCGCTGAAAATTCGTCACACCCACGTAAAGGCACACCTATTCGTAAAAAGCAGCG
CGAAGAGGCCCAACAGTTTATTAATACCTTACAAGGCGTTACTTTTCCCAACTCCCAACGTATTTATCTACAAGGCTCTC
GGCCCGATATTCAAGTGCCGATGCGTGAAATCCAACTCAGCCCGACGCAAATCGGCGGCAGTAAAAACGAACCACGCTAT
GAAGATAATGAGGCCATCCCGGTCTATGACACCTCCGGTCCCTATGGTGACCCACAAGCTAAACTGGATGTTCATAACGG
GCTGCCTAAACTGCGTGCCGCTTGGGTCGCAGATCGCCAAGATACTGAAGCGCTGGCATCTGTCAGTTCCGGCTTTACCC
AACAGCGTTTGGCTGATGAAGGCCTGGACCATTTACGTTTTGAGCATCTACCCCGCCCACGGAAAGCAGCCACTGGTCAA
TGTGTGACTCAGTTGCATTACGCCCGACAGGGGAAAATCACGCCAGAGATGGAGTTTATCGCCCTACGGGAAAATATGGG
CCGTGAACGTATTCGGGGTGAAGTCTTGCTTCAACAACATCCGGGACAAGCGTTTGGTGCCCATCTGCCGGAAAATATCA
CCGCCGAGTTTGTGCGTCAGGAAGTGGCGGCCGGCCGAGCCATCATCCCCGCCAATATTAATCACCCAGAATCTGAACCA
ATGATTATTGGCCGTAATTTTCTGGTCAAAGTGAATGCCAACATCGGTAATTCCGCCGTGACCTCTTCCATTGAAGAAGA
GGTAGAAAAACTGGTCTGGTCTACCCGTTGGGGTGCCGATACGGTGATGGACTTATCTACGGGCCGCTATATTCATGAAA
CGCGGGAATGGATCCTACGTAACAGCCCGGTCCCTATTGGCACGGTACCTATCTATCAGGCGCTGGAAAAAGTTAATGGC
GTGGCCGAAAATCTGACCTGGGAAATGTTCCGTGACACCCTGTTAGAGCAGGCAGAGCAAGGGGTAGACTATTTTACTCT
CCACGCGGGGGTCTTGTTGCGCTATGTGCCGATGACTGCCAAACGCCTAACCGGTATCGTCTCTCGCGGCGGTTCAATTA
TGGCAAAATGGTGCCTTTCGCATCATCAGGAAAACTTCCTGTATCAGCATTTCCGCGAAATCTGTCAGATTTGTGCAGCC
TATGACGTTTCATTATCACTGGGCGATGGCCTGCGCCCTGGCTCTATTCAAGATGCCAATGATGAGGCCCAATTCGCCGA
ACTGCATACCTTGGGTGAATTGACCAAAATCGCCTGGGAGTATGATGTACAGGTGATGATCGAAGGCCCAGGGCATGTGC
CGATGCAGATGATCCGCCGCAATATGACCGAGGAACTGGAACACTGCCACGAAGCGCCATTTTATACCTTAGGCCCACTG
ACCACGGACATCGCACCGGGCTATGACCACTTTACCTCAGGGATTGGTGCAGCGATGATCGGCTGGTTCGGTTGCGCCAT
GCTCTGTTATGTCACCCCCAAAGAGCACCTTGGTCTGCCGAATAAAGAGGATGTCAAACAGGGGCTTATTACTTACAAAA
TTGCCGCGCACGCCGCAGATTTGGCTAAAGGCCACCCCGGTGCGCAAATTCGTGATAACGCCATGTCCAAAGCTCGCTTT
GAGTTCCGCTGGGAAGATCAATTCAATTTGGCGCTTGATCCAGCAACAGCCCGCGCTTACCACGATGAAACCTTGCCGCA
AGAGTCCGGGAAAGTCGCTCATTTTTGTTCCATGTGCGGCCCGAAATTCTGTTCAATGAAAATCTCACAAGAGGTCCGCG
ATTATGCTGCGGCACAAGAACAAGCGGCCGCACAAGCACAAGCCGCTACACCAACCACCGCAGCACAACCAATAGACATC
ACGCAGCCAATTAATATGCTGCAATCAGGGATGGAAAAAATGTCGGCCGAGTTTCGCTCCCGTGGCAGTGAGCTATACCA
CCGCCCGGCGAATCTGAGTGCGGAGGCCAATAATGAGCCAACTTGA

Protein sequence :
MSNNTTSLPAENSSHPRKGTPIRKKQREEAQQFINTLQGVTFPNSQRIYLQGSRPDIQVPMREIQLSPTQIGGSKNEPRY
EDNEAIPVYDTSGPYGDPQAKLDVHNGLPKLRAAWVADRQDTEALASVSSGFTQQRLADEGLDHLRFEHLPRPRKAATGQ
CVTQLHYARQGKITPEMEFIALRENMGRERIRGEVLLQQHPGQAFGAHLPENITAEFVRQEVAAGRAIIPANINHPESEP
MIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNG
VAENLTWEMFRDTLLEQAEQGVDYFTLHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICQICAA
YDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPL
TTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARF
EFRWEDQFNLALDPATARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQEQAAAQAQAATPTTAAQPIDI
TQPINMLQSGMEKMSAEFRSRGSELYHRPANLSAEANNEPT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 72
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 67
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 67