Gene Information

Name : hemC (y0381)
Accession : NP_667719.2
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 425084 - 426025 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAATTATTCGAATTGCCACACGACAAAGCCCGCTCGCCTTATGGCAAGCACATTATGTTCAACATTTATT
GCAAGCCAATCACCCTGGTCTGCAAATCGAACTGGTCCCAATGGTCACCCGTGGGGATATCATTTTGGATACACCATTGG
CCAAAGTCGGTGGTAAGGGTTTATTTGTCAAAGAATTAGAGCTGGCGCTGCTGGACGGCAGAGCTGATATTGCCGTGCAT
TCGATGAAAGATGTGCCCATTGCTTTCCCCGAAGGGCTGGGTTTAGTCACGATTTGTGAACGTGAAGACCCGCGCGATGC
TTTCGTCTCGTCACATTATGCCCATCTGGATGATCTCCCTGCAGGCAGTGTTGTCGGTACCTCCAGCCTGCGCCGCCAGT
GTCAGCTACGCGAACGGCGACCAGACCTGATTATCCGCGATCTACGGGGCAACGTCGGTACCCGCCTTGCCAAACTGGAT
AATGGTGACTATCAGGCTATTATTCTGGCTGTCGCGGGTCTCAAGCGCCTCGGTCTGGAAAACCGAATTCGCTATGCCAT
GTCAGCGGAGGAGTCCCTCCCGGCTGTCGGCCAAGGTGCCGTAGGTATCGAATGCCGTCTGGATGATGACCATACCCGCC
AGTTGCTGGCTCCGTTGAACCATCGGCACACCGAATTACGGGTCTGTGCGGAGCGGGCAATGAATATTCGCCTTGAAGGG
GGTTGCCAAGTCCCGATCGGTAGCTACGCTGAACTGGAAGGTGATACTTTATGGCTACGGGCGCTGGTGGGAGCACCTGA
TGGCAGCCAAATGATCCGGGGTGAACGCCGTGGTCCGGCGGCAGAGGCTGAGCAGATGGGCATTGAACTTGCCGATGAGT
TGCTATCACGCGGCGCACGAGAAATCCTGGCGGCGGTTTATCTGGATAATCCTGCGCGATGA

Protein sequence :
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVH
SMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLPAGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLD
NGDYQAIILAVAGLKRLGLENRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAREILAAVYLDNPAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-83 62
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-83 62