Gene Information

Name : glnA (y3804)
Accession : NP_671098.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 4224248 - 4225681 bp
Length : 1434 bp
Strand : +
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGACAAATCCGGGAGATATAAGTATGTCCGCTGAACATGTTTTGACGATGCTGAATGAGCACGAAGTGAAATTTGTTGA
TTTACGTTTCACTGATACCAAAGGGAAAGAGCAGCACATCACGATCCCTGCTCATCAAGTCAACGCTGACTTCTTCGAAG
AAGGCAAAATGTTTGATGGCTCCTCGATTGGTGGCTGGAAAGGCATTAACGAATCCGACATGGTACTGATGCCAGACGCC
AGCACTGCCGTTATGGACCCGTTCTTCGCAGATTCAACACTGATTATCCGTTGTGACATTCTTGAGCCAGGCACCATGCA
GGGCTATGACCGCGATCCACGTTCTATCTCCAAACGTGCTGAAGACTTCCTGAAATCTTCAGGTATCGCTGATACCGTGT
TGTTCGGGCCAGAACCAGAATTCTTCCTGTTTGACGATATCCGTTTTGGTAGCAGCATCAATGGGTCACACGTATCCATC
GATGACGTCGAAGGCGCATGGAACTCCAGCACCAAATACGAAGGCGGCAACAAAGGCCACCGTCCTGCAGTAAAAGGCGG
TTACTTCCCTGTTCCTCCGGTCGACTCTGCACAAGACCTCCGTTCTGCCATGTGTCTGACGATGGAAGAGATGGGCTTGG
TGGTAGAAGCACACCACCACGAAGTGGCTACCGCGGGTCAAAACGAAGTGGCTACCCGCTTCAATACCATGACCAAGAAA
GCAGATGAGATCCAGATTTACAAATACGTCGTACACAACGTGGCGCACGCATTTGGTAAAACAGCGACCTTTATGCCAAA
ACCGATGTTCGGCGATAACGGCTCAGGTATGCACTGCCATATGTCTTTGTCCAAGAACGGTAATAACCTGTTCGCTGGCG
ACAAATACGGCGGCCTGTCTGAAATCGCCCTGTTCTACATCGGCGGTATCATCAAACATGCGAAAGCCATTAATGCCTTG
GCTAACCCGACCACCAACTCCTACAAGCGTCTGGTCCCAGGTTATGAAGCACCGGTCATGCTGGCATATTCAGCCCGTAA
CCGTTCAGCTTCTATCCGTATTCCTGTTGTTGCCAGCCCGAAAGCTCGCCGTATTGAAGCGCGTTTCCCCGATCCTGCGG
CTAACCCGTACCTGTGCTTCGCCGCGCTGTTGATGGCTGGCCTTGATGGCATCATCAACAAAATTCACCCAGGTGATGCG
ATGGACAAAAACCTGTATGACTTGCCGCCGGAAGAAGAAGCTGAGATTCCAAAAGTTGCCGGTTCACTGGACGAAGCCAT
GGCCGCATTGAACGAAGATCGCGAGTTCCTGACTCGTGGTGGCGTGTTCACCGATGATGCTATCGATGCGTATATCGAGC
TACGTAGAGAAGAAATGGATCGCGTGCGTATGACTCCGCATCCTGTTGAGTTCGAACTGTATTACAGCGTTTAA

Protein sequence :
MTNPGDISMSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHITIPAHQVNADFFEEGKMFDGSSIGGWKGINESDMVLMPDA
STAVMDPFFADSTLIIRCDILEPGTMQGYDRDPRSISKRAEDFLKSSGIADTVLFGPEPEFFLFDDIRFGSSINGSHVSI
DDVEGAWNSSTKYEGGNKGHRPAVKGGYFPVPPVDSAQDLRSAMCLTMEEMGLVVEAHHHEVATAGQNEVATRFNTMTKK
ADEIQIYKYVVHNVAHAFGKTATFMPKPMFGDNGSGMHCHMSLSKNGNNLFAGDKYGGLSEIALFYIGGIIKHAKAINAL
ANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVASPKARRIEARFPDPAANPYLCFAALLMAGLDGIINKIHPGDA
MDKNLYDLPPEEEAEIPKVAGSLDEAMAALNEDREFLTRGGVFTDDAIDAYIELRREEMDRVRMTPHPVEFELYYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 2e-99 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA NP_671098.1 glutamine synthetase VFG1399 Protein 3e-115 51