Gene Information

Name : y3669 (y3669)
Accession : NP_670966.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : ATP-dependent protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4076150 - 4078753 bp
Length : 2604 bp
Strand : -
Note : residues 9 to 867 of 867 are 44.41 pct identical to residues 6 to 899 of 902 from GenPept : >gb|AAG03480.1|AE004447_13 (AE004447) probable ClpA/B-type chaperone [Pseudomonas aeruginosa]

DNA sequence :
ATGGGAGCGATAACGGTGTATCAACGCGAACGTCTTTTTAATCGATTGGGCACTTTTGCCTATAAAACTTTTGTTGAAGC
CACCCGTCTTTGCCGCAGTTATCGGCATGAGTATGTGGAGCTTGAACATTGGTTAAAAATTCTCATGGATCAACAGCGTG
GGGATATTCCTGCTCTACTGACGCATTACGGACTGAGCCAGACGGTTATCTCCACGCAATTGGATCGCATTATTCAGCAT
ATGCCCGTCACCAAAGCATCGGTGCAGGATTTATCATCACGCTTGGAGTCCGTGGTCGAAGGCGGATTGGTGTTGAGCCA
ATTGATGGCGTCACCTTCTCCTATCCGTACCTCGCATATTTTACTGGCACTATTACAGGATACCCAGCATCAGCGCTGGT
TATACCGCCTGTGCGATGAATTCAAAAAGCTGCCGGTCCCACAGGTTGCAGAGGAATATGAAGGCCTATTAGTTAACTCC
ATTGAACAGACCAGCGAGGTTCAAAGAGGCGACGCATTAGTGACGGAAACGGACAGCAGCTCATCAAAAGAAGCGCATGC
GGCATTGAACAAATGGTGTAACGACCTTACCCAGCAAGCCCGTGACGGTGAGATTGACCCCGTTATTGGTCGTGAAGCAG
AACTGCGTCAAGTGATTGATATTTTACTCCGTCGCCGTCAGAACAACCCTATTTTGGTTGGGGAAGCGGGGGTCGGTAAA
ACGGCGGTGGTTGAAGCGCTAGCGCGAAAACTGGCCAGTGGCGATGTCCCTCCGCTGTTGCAAGGGGCGCGTCTGCTTTC
TCTGGATTTGGGGAGGATGCAAGCCGGTGCCAGTATGCGCGGTGAATTTGAATCACGTCTTAAATCCCTGATCGATGGCA
TCAGCCAATCGGATACCCCGGTTATTCTGTTTTGTGATGAAGCCCATACGTTGGTGGGGGCAGGCGGGCAGGCGGGCACG
GGGGATGCGGTCAACCTGCTTAAACCGATGTTGGCGAGGGGCGCATTGCGCATGATCGCCGCCACCACCTGGTCAGAGTA
TAAACAGTTTATTGAACCTGACGCCGCGCTGACCCGGCGTTTCCAGCGGGTATTGATTGGCGAGCCAAACGAATCTACCG
CCGTCGATATGCTACGGGCGATTGCGCCACATTTTGCTCAACATCATAACGTCACTATCCGCGACGGTGCCATTCACGCG
GCGGTGCGCCTGTCATTACGCAACCTGCCTTCCCGGCAGTTGCCCGATAAAGCCATCAGTCTGCTCGACACCGCTTGCGC
GCGGGTCGCGCTCAGCCAATATGCCCAACCACAGGCGATTGAACAGTTATCGGCCCAACTGGATGTGCTCAAAACCGAGC
ATCAATATCTGGTACGGGAGAAGCAACTGGGCGAAGCGGTTGATCAACGGCTAGATGACGTTCAGACACAGATCCAGGCG
TTTGAACATGAACTAACCGCCTTGCAAAGCCGCCATCTGCATGAGCAACAGCTAGTGAGGGAGGTCCTGCCGGAGGGAGA
AGGCAGTGGCATGATGACGGAAAATGCCCGCTGGGGTGAACTGATGGCGTTACAGGAAGCGTCGCCACTGGTCTATCCAT
GGGTTGATGAGCAGAGCATCGCCGCGGTGCTTTCCGATTGGACCGGGATCCCGTCCGGCAAAATGTTGCAGGACGATATT
GAATGCGTCCTGAATCTTGAACAGCGTCTCGGTGATCATATTTTCGGGCAACGCAACGCTATCAAAGAGATTTCGCAGGC
GATACGTATTGCTCGGGCGGGCATCCAGTCTCAGGAGCGGCCACTCGGGATCTTCCTGCTGGCGGGGTCAACCGGTACGG
GCAAAACAGAAACGGCCAATGTACTGGTCGAAACCTTGTATGGCGGTGCTCATAACCTTATTACCTTCAATATGAGTGAG
TTCCAAGAGGCGCATACCTTATCCACGCTGAAAGGCGCACCTCCGGGCTATGTCGGCTATGGCAAGGGGGGGAAATTAAC
CGAAGCGGTAAGACGCAAACCTTATTCGGTCATCCTGCTTGATGAGTTTGATAAAGCTCACGCCGATATTCAGGACGCCT
TTTATCAGGTCTTCGACAAAGGGTGGATGGAAGATGCCGAAGGGCGTCGGGTCAGTTTCCGCCAGTGTTTCATCTTACTG
ACCTGTAATCAGGGCGCGGAAGAGATCGAACAGGCTTACCTCACCGCCAACGATATCAAACCCGGTGCATTAAAACCGTT
GGTATACGACGCCCTGTTGCGCCGCTTTGCGCCAGCGCTGTTAGCCAGGGTCAATATCATTCCTTATATCCCATTAGATC
AGGACGCTCTGGCACAGATCGCCTCTCATCATCTTGCGCGCTTACAAACGCGCCTGTGGGATGAAATTGGTGCCACTTTG
GTGACCGAGGGGGATATCCCCGGCTGGATCGCCTCACGGGTTTGCAGCCATCCGAACCATGGTCGTGCGGTGGAAGAACT
CTTGCGTCAAACCTTACTTCCCGCTGTTGGCAATGAAGTGTTGAAGCGTCGCCATGAGGCTGAACCGCTGAGAGAGATAC
GCCTGATTGTTGAGGAGACAGAACTGAGTATTGAGTTCGCGTAG

Protein sequence :
MGAITVYQRERLFNRLGTFAYKTFVEATRLCRSYRHEYVELEHWLKILMDQQRGDIPALLTHYGLSQTVISTQLDRIIQH
MPVTKASVQDLSSRLESVVEGGLVLSQLMASPSPIRTSHILLALLQDTQHQRWLYRLCDEFKKLPVPQVAEEYEGLLVNS
IEQTSEVQRGDALVTETDSSSSKEAHAALNKWCNDLTQQARDGEIDPVIGREAELRQVIDILLRRRQNNPILVGEAGVGK
TAVVEALARKLASGDVPPLLQGARLLSLDLGRMQAGASMRGEFESRLKSLIDGISQSDTPVILFCDEAHTLVGAGGQAGT
GDAVNLLKPMLARGALRMIAATTWSEYKQFIEPDAALTRRFQRVLIGEPNESTAVDMLRAIAPHFAQHHNVTIRDGAIHA
AVRLSLRNLPSRQLPDKAISLLDTACARVALSQYAQPQAIEQLSAQLDVLKTEHQYLVREKQLGEAVDQRLDDVQTQIQA
FEHELTALQSRHLHEQQLVREVLPEGEGSGMMTENARWGELMALQEASPLVYPWVDEQSIAAVLSDWTGIPSGKMLQDDI
ECVLNLEQRLGDHIFGQRNAIKEISQAIRIARAGIQSQERPLGIFLLAGSTGTGKTETANVLVETLYGGAHNLITFNMSE
FQEAHTLSTLKGAPPGYVGYGKGGKLTEAVRRKPYSVILLDEFDKAHADIQDAFYQVFDKGWMEDAEGRRVSFRQCFILL
TCNQGAEEIEQAYLTANDIKPGALKPLVYDALLRRFAPALLARVNIIPYIPLDQDALAQIASHHLARLQTRLWDEIGATL
VTEGDIPGWIASRVCSHPNHGRAVEELLRQTLLPAVGNEVLKRRHEAEPLREIRLIVEETELSIEFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-148 45
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-107 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-107 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
y3669 NP_670966.1 ATP-dependent protease VFG2076 Protein 4e-156 44
y3669 NP_670966.1 ATP-dependent protease VFG2084 Protein 2e-123 41