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Name : HMWP2 (y3410) Accession : NP_670708.1 Strain : Yersinia pestis KIM Genome accession: NC_004088 Putative virulence/resistance : Virulence Product : nonribosomal peptide synthetase Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1020 EC number : - Position : 3775907 - 3782311 bp Length : 6405 bp Strand : + Note : residues 194 to 2089 of 2134 are 36.15 pct identical to residues 23 to 1846 of 2041 from GenPept : >gb|AAC69587.1| (AF091251) Ybt peptide synthetase HMWP2 [Yersinia pestis] DNA sequence : TTGGGCCGTTGGTGGAGATATAAGTGGATCACTTTTCATCCGTCGTTGACAATAAAGCCAGTTACATCAATAAAATCAGC CACATCAATAAAATCAGTTGCATCAATAGAACCAGTTGCATCAACAACCTGGCTATCCGATGAGGAGGCGGTTGGTTGGC TGCCCATCAGCGCTAAAACTGAAGCCGCACTCTTGGCGACGGCGCGCCAGCTTGCCGAGGTCTTGTCACAGCATACGGCG CTTGCTCGGGCGGTTGTCGCTGCGTGGCGCACTAAACGTAGCCATCATTTTCCCATCCGTGCCTTGATTCAATATCACTC ATTAAGTGATTTGATCGCACAGTTACATCAAGTCACCGGCGAGAAAAGTGATCCCCGCTGTCGCTTTGAAAAGGCGCAAT CGCCCAAACAATGGTTGGCGGGAGGGGCTTTTGACTGGGCAGCAGTCACCCCCTCTGAAGGGGCCGTTAGTGCTGAGGTG TTGGCGCTTTTGCCTCTTTATCCTTTTACTCGCCAGCGCTATTGGGCTGAAGGTCTGCTGGCAGAGAGTACCCCCTTATC TTCCCCTTCGGTTATTGCCCATCCCCTTGATTTTTCATTTGTGCGCACTTGGGTGGCAGAGACACTCGCTATCGCGTCTG GAGCGTTATCTGATGAGGATGATTTGCTGAGTTTAGGTTTAGATTCTTTGCAGATGTTGGATCTGGTGGATGAGTGTAAA AAACGCCATATCACTTTGACGTTGGCAAGGTTGTTTGAAAAAACAACCCTGGGAGCATGGGAACAGTATTGGGACAGTAT TTGTAGAAGCGGTGTCTGCGGGGAGAGTGTCAGTGCGGTTACCCCACTCACAGAAGAGCAAACCACGGATGAGTACTGGC AGGGGGAGCCTTTTGTGCTTACCCCTGTGCAGCAAGCCTATTGGCAAGGGCGTCAGAAGGGGCAAACGTTGGGGCAGGTT GCCTGTCAGGTTTATCTGGAGTTGGATTGCCCGTCGTTAGCGGATGAACGTCTTCATCAGGCGGTGACGCAATTATTCCA CCGTCATGAGCTTTTGCGTATGCGTATTAACGAGCAAGGGATGGGGGTTATCCAGGAAATCGAGCCGGTGACGGTAACGC AATATCACTGGGATCAGCTCTCTGCAAGGGCTGGTGCAAAGGAGCGCTACGCGCTACGGGCGCGTTTATCCCATCGTATG GCTGATTTAACTGACGAGAGTGGGTTCCAATTGATTGCCAGCCATGATGGGCAAAACACCCGTTTGCACATTAATGTGGA CATGGTGATTGCTGATGCCATGAGTTTGCAAATTCTGTTGGAGGAGCTAGGGCTGCTCCTTTCGTCGCAGAATACGCCAT TTGCACCGTTGGATTACCACTTCCCGCAATATTTGTTGGAGCAAAAATCAACACCATCAACGGGTGAGAGCGAAGCTTAC TGGCAACAACGGTTAATCGCAGGTTTACCGTTAGCCCCGCAACTGCCATTGGCAATAAAACCGGAGCAGATAGATAAACC TATTTTCCAACACCGTGAGTGGCGTTTAGCGTCAGAACATTGGGCTAAATTACAACAAATAGCCCGCCAACATAGGTTAA CGCCCTCCATGTTATTGGCGGGTTGTTTTGCTGAAACATTACGGGGTTGGGCGAAATTGCCTGACTTTTCGCTGAACTTA ACGATTTTTAACCGTCGTGGCGCACATCCACAATTGGCAAAATTGGTCGCTGATTTTACGTCCTTGCTCATACTGGCATG TGAGGTTAAAGAAAACGAAAGTTTACTGGATCATTTCCGCAGGCTGAATCAGCAGTTTATGGTTGATCTGGATCATGGGG ATTACAGCGCAGTGCACGTGTTGCGTCAGTGGTCTCAACAGCGGGGCGAACAGGTTACTCTGCCGGTTGTCTTCACCAGT AATCTTGGGCGTGAATTGCTCGGGGAAAATGCACCAGGGGCGCTGCATTATTTGGTTTCTCAGACACCACAAGTGTGGCT AGACTGCCAGGTGATGGAGTATCAGAAAGCCCTGTTGATCAGTTGGGATACCGTGGACGCACTCTTCCCCGAAGGGATGC TTGATCAGATGTTTGCTTTTATGCAGCAGCTTCTTCAATCCATTGTCGAAAATGAGCAAGTCTTACAGTCACCTGTTCAG GCGTATGTGGATGACAAGGTGCTGGCGCATCGCCAACAGCCGTTATCGGGTGTCCACGGGGTGCCTTTTGAGGCCAAAAC CCTGCATCAGGGCTTTTGGCAGCAAGTCGCATTGGTCCCGAATAACATTGCTGTCATCAATGCCTCCGGTGTCTTGACGT ATAGGGAAATGGCAATACGAGTCGGCGATTTGGCGGGGTACTTACAGCAGCGCATTGCACGACAGGGCCATGTGGGTATT TGTTTACCTAAAGGGATTGAGCAAGTGATCGCGGTGCTGGCGGTATTGTCCATTGGGGCGGTGTATGTGCCGTTGGATAT TACCGCGCCCTCCGAACGCTTACAGCAACTGATCGCGCAGGCGGATATTGGCGTATTGATTAGCGATCACGAGATATCCG CTAACTGCGACACAGTGAATATCAACATAACAGGCGGTTTTCCATCGCCTTTTACCCCGTCTGTTTTTACCTCATCTGCT GCTGCGCCCTCTATTTTTGTACCCTCTATTTTTGTACAACCTGATGAGCCAGCCTATCTGATTTTTACCTCAGGCTCGAC GGGGGTGCCTAAAGCGGTGGTGGTGACACATCAGGCTGCAATGAATACGATTGATGAGATTAATCGCCGCTATGTTGATG ATGGGAAGATCATCTTGTTCGCACTCTCGGCATTAAATTTCGATCTCTCGGTTTATGATATTTTTGGTCCTTTGTCTGTC GGCGGCTCCCTGGTATTGCCCAACGCGGGCGATGAAAAAGAAGCTAAACAGTGGCTGTCAGCACTGCATCAACATCAAGT GACACATTGGAACAGTGTTCCTGCCTTATTTGAAATGCTGCTGATCGCCGCTGAGCAAGGTACGCAAGCTTTGCCTCGTT CGTTACAACAGGTGTTGTTGTCGGGGGATTGGATTGGGTTAGACCTTCTCCCCAGGCTGAGAGCGCTTGGTAGCCAAGCA CGTTTCACCACGCTGGGCGGCGCCACAGAAGCGGCCATTTGGTCTAATGCGCTGGATATCGCGGTGATCCCTGAAGAGTG GGTATCCATACCTTATGGTTATCCACTGGCCCATCAATATTATCGTGTCGTTGACCAGGCTGGCAGAGATTGCCCTGATT GGGTGACAGGGGAACTGTGGATTGGCGGTAGGGGAGTGGCATTAGGTTATTACCGGGAGCCAGAAAAAACGGCGGCGCAA TTTGTCTCTGTTCATCGCGCGGGGTTTTATCGAACAGGCGATTATGGTCGCTTCTGGCCTAATGGGTGTCTGGAGTTTTT GGGGCGACAGGATAGACAAATAAAACTGCATGGTTATCGCATTGAATTAGCGGAAATTGAAGCTGTCGCAGAGCATCTGG CAACGATTAAACGTGCTGTGGTTTTATATTTGGATCAGCCACAAAAGCATTTATACCTGTTTGTTGAGCCTCAGAATCAG GTATCCACTCTCTTCTCCGCAACCGTTGATGATGTATTACCTGAAACCAGACTTGTAACGGATATTCGTGAACAAGAAAA CACGATAACCGCTTTTCTGTTATGCCATGTGCTCAGCAATGTTCTCAAGCTCGATCTGGCAGAGTATCAGTCTACGCAAG TATTGCAGGAAAAAGGGGGGATTAGCGAAGCCTACCAACCGCTATTTTTAGCCTGGCTCCATTGGTTGGTTGAGCAAGGG GTTTTACTTTCTCGCGATGACCAGTTTAAAACCACAGGAATTCAGCCCGTACGCCCTGAGGTGACTGAACCACACCTGTT ACCGCTCTTGATGACGTTAGAGCAAAAAGCGTCATGGATTGGCGAGGTGGTGACTGGGCGGGGAAATCCACTGTTATTGT TGGACGACACGCTCCTGTCGCCAGAAATTTTAGTCGCCAATACACATGATGCCCAAGTGGTTATTGATGTGCTATGTCAG CGCATTGCTCGTTTATCTCGGCAATTACAACGGCCTGTTAATGTCACCGAATTGAATGGGCGAACGGGGCTGTTTGCCAG CCGGGTATTGAGCCGGTTGGGAACTGAGGTGCTGAGTTACTGTTTGTTGGAATCTGCAAATTCATTGCGTCAACACGCAA AGTATCGTTTATCTGGCTATTCCCATGAAACAGATGTGATTGCAACACCCGATGAACAGCAACAACTTGCCGATATTCTG ATCGTCAATAATTCACTACACCGATTTGATGCCCTGCCTGAGGGGATTGCCATGCTGCAATCCCTTTGCCACGGAGGGAC GGAAATTGTCCTGTTTGAAAGCCTGGCACTAAGCCCACTGTCGCTATTAACGGTGTTGTTGTTACAACATCCCAATGGTT TTAGGGATCAACGGCAAGGGGCACTTTCGCCGCTCTTGGATTTACCCGCCTGGCAGTCGTTGTTAACGGATTCAGGTATT GCCATCCAGCAACTCAGTATTATTGAACCGTATTCTGCACTCTTTGTCTGTCAACCACAGATAACGAAAGTGCCCGTTTC GCGTGAACAGATAAAGCAACATTTACAGCAACATTTACCCGCCTATATGGTGCCATCGTCTATCACGGTACTGGAGACAT TGCCACTGACACCGAACGGCAAAATTGACCGGACATCGTTATATAAACAGGCCGTTGAGTATGGGCAGCTAAGCCATGAT GGTGAAGCGCCTCGCGTGTTATCTGCCCAACAGAAGCCGCCAGATGAACGGGAACGGTCTGATAAACGAGAACTGTCTGA TAAAAAAGAACAGTGCGTCGCTCGCCTTTGGCAGCAAGTGTTAGGGGTTACGCCGCAATCAGATAGCAACTTTTTCCTGT GTGGTGGTGATAGCCTTCATGCCACGCGCATCGTGGCCTTGTTGGAAAAAGAGGGCACGGTTGGCGTGCCATTGTCTCAG GTGTTTTTATTGCCGGTGTTAAGGGATTTTGCTCACAGTCTGGCGTTCCGCCATGCGCCTGTACAGGAGGCGCAATTAGT TCATTGTGCCGCCCAACGTTATTCGCCCTTTGAGCTAACCGATGTGCAGCGAGCATATTTAATGGGGCGGCAATCGGGGT TCCCACTGGGTGGCGTGGCAACGCACTATTATCAGGAATACGAGTATCAGGAATACGAATATCAGGAAAATGAAATTTAT CAGGAACATGAAAGCCATCAGCAATATAAAGGCACACCGTTTGACCGGGAACGATTAGAGCGGGCCTTAACTCTGCTGGT AGCTCGTCATGATGCGTTGCGTATTGTGTTTGATGAACAGGGTACACAGCGTGTGTTACCCCATCAACCGTCCCCGGCGC TTCAGGTTATTCATTGCGGTGCTGTGGAGTGGGAAACCGTGACGGCGACTCAACGGGATCGGTTGTCACATTATGTCTCT GAACCGACCCAATGGCCGTTGTTCCACGCGACCTTAATTCAGTCTGATGAGGGTAGAAATCGTTTTTGCCTTGGGCTGGA TAATCTGGTGTTAGACGGTTTGAGTATGCAGATCTTCTTTAAAGAGTTGGCTGTCTTGTATGAGGACCATACCGCCACGC TACCCTCCGTGGAGATTGGTTTCCGCGATTATCTGCTCGCTGAATCATCGTCACCTCATCGCCAAGTCTCTGAGGATTAT TGGCGAGAAAGTCTCCCAATGTTACCGGATGCACCGCGCTTGCCATTGGTGTGCGATCCCGCCTTAGTGGGCACGCCTAA ATTTAAGCGTTGGCAAGCTGTCTTGTCGGCCTCTGATTGGCAGATGTTATTGCATAAAGCCAAACAGCATCAAATTACAC CCTCTTGCTTACTCCTGACTTGCTATGCCCAAGTTTTGGCGAAGTGGTCTGAATCAGCATCACTCACCATCAATGTCACC TTGTTTGATCGCAAACCTTGTCATCCAGATATTAACCATATTATGGGCGATTTTACTTCTCTGCTCTTATTAGGTTGTCG ACAAGAGAAAGGGGAAGGGTGGTTGGCAACGGCTCAGCGTATTCAGCAACAGCTATGGCGAGATCTGGAGCACCGTGAAG TTTCCGCCGTCTGGGTGCTCAGGGAGTTAAATCGCCAGCGGGGAACAACCCATATTCACATGCCGGTGGTGTTTACCAGT GCCTTGGGCGCACAAGTGGATGGTTACCCTGACAGCGCATTCCAAGCCCTCTTTGGGGATTTCTCAAGACACCGCAATTG TGGATTGACCATCAGGTTTTCGAACGTGATGGCGAATTGCATTTTAACTGGGATGTCGTTGAGGCTTTATTTCCAGCTGG CGTGA Protein sequence : MGRWWRYKWITFHPSLTIKPVTSIKSATSIKSVASIEPVASTTWLSDEEAVGWLPISAKTEAALLATARQLAEVLSQHTA LARAVVAAWRTKRSHHFPIRALIQYHSLSDLIAQLHQVTGEKSDPRCRFEKAQSPKQWLAGGAFDWAAVTPSEGAVSAEV LALLPLYPFTRQRYWAEGLLAESTPLSSPSVIAHPLDFSFVRTWVAETLAIASGALSDEDDLLSLGLDSLQMLDLVDECK KRHITLTLARLFEKTTLGAWEQYWDSICRSGVCGESVSAVTPLTEEQTTDEYWQGEPFVLTPVQQAYWQGRQKGQTLGQV ACQVYLELDCPSLADERLHQAVTQLFHRHELLRMRINEQGMGVIQEIEPVTVTQYHWDQLSARAGAKERYALRARLSHRM ADLTDESGFQLIASHDGQNTRLHINVDMVIADAMSLQILLEELGLLLSSQNTPFAPLDYHFPQYLLEQKSTPSTGESEAY WQQRLIAGLPLAPQLPLAIKPEQIDKPIFQHREWRLASEHWAKLQQIARQHRLTPSMLLAGCFAETLRGWAKLPDFSLNL TIFNRRGAHPQLAKLVADFTSLLILACEVKENESLLDHFRRLNQQFMVDLDHGDYSAVHVLRQWSQQRGEQVTLPVVFTS NLGRELLGENAPGALHYLVSQTPQVWLDCQVMEYQKALLISWDTVDALFPEGMLDQMFAFMQQLLQSIVENEQVLQSPVQ AYVDDKVLAHRQQPLSGVHGVPFEAKTLHQGFWQQVALVPNNIAVINASGVLTYREMAIRVGDLAGYLQQRIARQGHVGI CLPKGIEQVIAVLAVLSIGAVYVPLDITAPSERLQQLIAQADIGVLISDHEISANCDTVNINITGGFPSPFTPSVFTSSA AAPSIFVPSIFVQPDEPAYLIFTSGSTGVPKAVVVTHQAAMNTIDEINRRYVDDGKIILFALSALNFDLSVYDIFGPLSV GGSLVLPNAGDEKEAKQWLSALHQHQVTHWNSVPALFEMLLIAAEQGTQALPRSLQQVLLSGDWIGLDLLPRLRALGSQA RFTTLGGATEAAIWSNALDIAVIPEEWVSIPYGYPLAHQYYRVVDQAGRDCPDWVTGELWIGGRGVALGYYREPEKTAAQ FVSVHRAGFYRTGDYGRFWPNGCLEFLGRQDRQIKLHGYRIELAEIEAVAEHLATIKRAVVLYLDQPQKHLYLFVEPQNQ VSTLFSATVDDVLPETRLVTDIREQENTITAFLLCHVLSNVLKLDLAEYQSTQVLQEKGGISEAYQPLFLAWLHWLVEQG VLLSRDDQFKTTGIQPVRPEVTEPHLLPLLMTLEQKASWIGEVVTGRGNPLLLLDDTLLSPEILVANTHDAQVVIDVLCQ RIARLSRQLQRPVNVTELNGRTGLFASRVLSRLGTEVLSYCLLESANSLRQHAKYRLSGYSHETDVIATPDEQQQLADIL IVNNSLHRFDALPEGIAMLQSLCHGGTEIVLFESLALSPLSLLTVLLLQHPNGFRDQRQGALSPLLDLPAWQSLLTDSGI AIQQLSIIEPYSALFVCQPQITKVPVSREQIKQHLQQHLPAYMVPSSITVLETLPLTPNGKIDRTSLYKQAVEYGQLSHD GEAPRVLSAQQKPPDERERSDKRELSDKKEQCVARLWQQVLGVTPQSDSNFFLCGGDSLHATRIVALLEKEGTVGVPLSQ VFLLPVLRDFAHSLAFRHAPVQEAQLVHCAAQRYSPFELTDVQRAYLMGRQSGFPLGGVATHYYQEYEYQEYEYQENEIY QEHESHQQYKGTPFDRERLERALTLLVARHDALRIVFDEQGTQRVLPHQPSPALQVIHCGAVEWETVTATQRDRLSHYVS EPTQWPLFHATLIQSDEGRNRFCLGLDNLVLDGLSMQIFFKELAVLYEDHTATLPSVEIGFRDYLLAESSSPHRQVSEDY WRESLPMLPDAPRLPLVCDPALVGTPKFKRWQAVLSASDWQMLLHKAKQHQITPSCLLLTCYAQVLAKWSESASLTINVT LFDRKPCHPDINHIMGDFTSLLLLGCRQEKGEGWLATAQRIQQQLWRDLEHREVSAVWVLRELNRQRGTTHIHMPVVFTS ALGAQVDGYPDSAFQALFGDFSRHRNCGLTIRFSNVMANCILTGMSLRLYFQLA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| YPO0778 | YP_002345834.1 | siderophore biosysnthesis protein | Virulence | HPI-2 | Protein | 0.0 | 99 |
