Gene Information

Name : iutA (y3385)
Accession : NP_670684.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : aerobactin OM receptor
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1629
EC number : -
Position : 3731487 - 3733667 bp
Length : 2181 bp
Strand : +
Note : ferric aerobactin receptor precursor (cloacin receptor); residues 9 to 726 of 726 are 66.25 pct identical to residues 11 to 732 of 732 from GenPept : >gb|AAD44750.1|AF141323_21 (AF141323) IutA [Shigella flexneri]

DNA sequence :
ATGAAACACAAACACCTCTGGGTATTAAATCCGTGTCTGCTGGTCATGCTCACACCAGCGGCGTGGGCAGAGGATCAACT
TGTGGTTTCAGCCAACCGCTCACACCGCAGCGTGGCAGAAATGGCGCAAACAACTTGGGTGATTGAAGGCCAGGAACTTG
AACAACAAGTTCAAGGCGGCCTGGAAATCAAAGACATCTTGGCTCAATTGATCCCAGGTATCGACGTCAGCAGCCAAGGC
CGTACCAACTACGGCATGAACATGCGTGGCCGCTCAATCATGGTGATGATCGACGGCGTGCGGCTGAACTCTTCACGTAG
CGACAGCCGCCAACTCGATTCGATCGATCCGTTTAATATTGCACACATTGAAGTCATCTCCGGTGCGACGTCACTTTATG
GCGGGGGTAGCACGGGGGGCTTGATCAATATCGTGACCAAAAAAGGCCAGGAAGGAAAACAGGTTGAGTTGCAAATTGGC
GGCAAAACCGGCTTTAACAGCCATAACGACCACGATGAGAACATCTCGGCCGCCATGAGTGGGGGGACTGAGCGCGCATT
CGGCCGATTCTCTGTTTCTTATCAACGTTATGGGGGGTGGTACGACGGCAAAGGCAATGAGGTTTTGATCGACAACACCC
AGACCGGCTTGCAATATTCTAACCGTCTGGACGTGATGGGCACGGGAACCCTCAATATCGACGAAAACCAGCAATTGCAG
CTAACCACTCAGTATTTCAACAGCGAATCCGATGGCAAACACGGCTTGTATCTGGGGCAAAACTTCTCAGCAGTAACGGG
TACCGGGCAGGCCTCCAACAGCGCAGCGCTAAATTCAGACCGTATTCCGGGTACCGAACGCCATCTCATCAACTTGCAAT
ACTCCAACACGGATTTCTGGGGGCAGGATTTAGTGGCGCAAGTGTATTACCGTGATGAATCACTAACCTTCTACCCATTC
CCAACACTGAAAGATGGCAAGGTGAGCACTATCGGTGCATCACAGCAAAAAACCGATTTCTACGGCAGTAAACTGACATT
GAACAGTGAACCTATCGATAGCCTAACACTGACTTACGGTATCGATTTGGAACATGAAAGTTTCAATGCCAATCAACAGT
TCTTTAATCTGGCGAAGGCACAGCAATCCGGCGGCATGACGTTAGAAAATGCCTACAACGTTGGCCGTTACCCAAGTTAT
ACCACCACCAACCTGGCTCCCTTCTTACAAACCCGCTATGACATCAACCCGATTTTCACTCTGAGCGGCGGTGTGCGTTA
CCAGTACACAGAGAACAAGGTTGATGATTTTGTGGGTTACGCACAACAACAAGCGATTGCCAGCGGCTCCGCGACTTCCG
CTGATCCCGTACCTGGTGGGAAAACGGATTACAACAACTTCCTGTTCAATGCCGGTTTACTGGCGCACCTGACAGAAAGC
CAGCAGACCTGGTTCAACTTTTCACAAGGATTTGAGATCCCGGATCTGGCGAAATATTACGGTTCTGGCTCCTACACGCT
GGTTAACGGTCACTATCAGTTGCAAAACAGTGTCAACGTGAATGACTCCAAACTGGAGGGCATCAAGGTTGATTCCTATG
AGCTGGGCTGGCGCTATACCGGCGATAACCTGCGCACCCAAATGGCGGGTTATTACTCGCTTTCTGATCAGACTATCTCG
ATCAACAAAACAGACATGACCATCAATGTGTTACCGGATAAGCGCCGAATCTATGGGGTAGAAGGCGCAGTAGATTACTT
CTTCGATAACAGCGAATGGAGTGCCGGTGCAACATTTAACCTAATTAAGTCGGAAACTAAGGTTAGCGGTAAGTGGCAGA
AACTGACTATCGATGCTGCCAGCCCGTCGAAAGCCACCGCCTACATTGGCTGGGCACCGGGTGATTGGAATCTGCGCGTG
CAATCCCAACAAACGTTCGATGTTTCCGATAGCAAGGGTGACAAAATAGACGGTTACAACACCATCGATTTTCTCAGTAG
TTACGCCCTACCCGTGGGAAAACTCAGTTTCAGTATCGAAAACTTGCTGGACAAAGAGTACACCACCGTTTGGGGTCAGC
GCGCACCGATTCTGTATAGCCCAACCTACGGCTCACCCAACTTATACAGCTATAAGGGCCGTGGCCGGACTTTTGGTGTG
AACTACTCAGTGTTGTTCTGA

Protein sequence :
MKHKHLWVLNPCLLVMLTPAAWAEDQLVVSANRSHRSVAEMAQTTWVIEGQELEQQVQGGLEIKDILAQLIPGIDVSSQG
RTNYGMNMRGRSIMVMIDGVRLNSSRSDSRQLDSIDPFNIAHIEVISGATSLYGGGSTGGLINIVTKKGQEGKQVELQIG
GKTGFNSHNDHDENISAAMSGGTERAFGRFSVSYQRYGGWYDGKGNEVLIDNTQTGLQYSNRLDVMGTGTLNIDENQQLQ
LTTQYFNSESDGKHGLYLGQNFSAVTGTGQASNSAALNSDRIPGTERHLINLQYSNTDFWGQDLVAQVYYRDESLTFYPF
PTLKDGKVSTIGASQQKTDFYGSKLTLNSEPIDSLTLTYGIDLEHESFNANQQFFNLAKAQQSGGMTLENAYNVGRYPSY
TTTNLAPFLQTRYDINPIFTLSGGVRYQYTENKVDDFVGYAQQQAIASGSATSADPVPGGKTDYNNFLFNAGLLAHLTES
QQTWFNFSQGFEIPDLAKYYGSGSYTLVNGHYQLQNSVNVNDSKLEGIKVDSYELGWRYTGDNLRTQMAGYYSLSDQTIS
INKTDMTINVLPDKRRIYGVEGAVDYFFDNSEWSAGATFNLIKSETKVSGKWQKLTIDAASPSKATAYIGWAPGDWNLRV
QSQQTFDVSDSKGDKIDGYNTIDFLSSYALPVGKLSFSIENLLDKEYTTVWGQRAPILYSPTYGSPNLYSYKGRGRTFGV
NYSVLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iutA NP_839219.1 ferric siderophore receptor Virulence SHI-2 Protein 0.0 66
iutA NP_709458.2 ferric siderophore receptor Virulence SHI-2 Protein 0.0 66
iutA AAD44750.1 IutA Virulence SHI-2 Protein 0.0 66
iutA AAK71635.1 IutA Virulence SHI-3 Protein 0.0 66
iutA YP_002414042.1 Ferric aerobactin receptor Virulence Not named Protein 0.0 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iutA NP_670684.1 aerobactin OM receptor VFG0619 Protein 0.0 66
iutA NP_670684.1 aerobactin OM receptor VFG1085 Protein 0.0 66
iutA NP_670684.1 aerobactin OM receptor VFG0936 Protein 0.0 66