Gene Information

Name : iucC (y3383)
Accession : NP_670682.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : aerobactin synthetase (subunit beta)
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG4264
EC number : -
Position : 3728342 - 3730090 bp
Length : 1749 bp
Strand : +
Note : aerobactin siderophore biosynthesis; residues 5 to 579 of 582 are 65.79 pct identical to residues 2 to 577 of 580 from GenPept : >emb|CAA53709.1| (X76100) iucC [Escherichia coli]

DNA sequence :
ATGATCACCACCGATTACGCTAACTGGCAGCAGGTTAATCGCCACATGATCGCTAAAATCCTTAGCGAACTGGAATATGA
ACGCACTCTGCATGCTGAATTACACGGTGAAACAGGGCGCATCACCTTGCCCGGCGCGGTTTACACCTTTAACGGCAAGC
GGGGTATCTGGGGTTGGCTACATATTGATCCTGCCACGCTGCGCTGTGAGGGTGTGCCGCTCGCCGCTGACCACATGCTG
CGCCAACTGGCGCTCGTGCTGAAGATGGACGATTCGCAGGTCGCAGAGCACCTTGAAGATTTGTACGCCACACTGCGTGG
AGACATGCAATTACTCTCCGCTCGCCACGGTATGAGTGCGGAAGCGTTGATCGCCCTTAATGATGATGCCCTGCAATGCC
TGCTGGCCGGTCACCCGAAATTTATCTTCAACAAAGGCCGCCGCGGCTGGGGCTTAACCGCCCTGCAACACTATGCGCCC
GAATATCAGGGCCAATTTCGTCTGCATTGGGTCGCAGCCAAACGCGGCAGCTTTATCTGGTGCGTGGATGCCGAATACCC
GTTGGACAACTTGCTCAACAGCGCCATGGACCCCGCCGAACGCCAACGCTTTGATCGCCGCTGGCGTGAGTGCCAATTGA
ATGATGATTGGGTCCCGGTGCCTTTACATCCGTGGCAATGGCAGCAAAAAATTGCCTTGCACTTCCTACCACAACTTGCC
GAGGGTGAACTGATCGAACTGGGTGAATTTGGCGATCACTATCTGGCGCAACAATCGTTACGCACATTAACCAATGTCAG
CCGCCGTGTGCCATTTGATATCAAACTGCCACTCACCATTTACAACACCTCTTGTTATCGTGGCATCCCAGGCAAATACA
TCAGCGCAGGCCCCGCGGCTTCGCGCTGGTTGCAGCAAGTCTTCGCACAAGACCGCACACTGCATGAAAGCGGGGCTGAG
ATCCTCGGTGAACCCGCCGCAGGTTATATGCTGCACCAGACCTACGCCACACTTGCCAAGGCGCCTTATCGCTGCCAGGA
AATGCTCGGTGTGATTTGGCGAGAGAATCCGTCCTGCTATTTGCGAGAGGGTGAACATGCCATTTTGATGGCGACGCTGA
TGGAAACCAACAATCAGGGTCATCCGCTGATCGCGGCCTATATTGCACGTTCGGGGTTAAGTGCTGAAGCCTGGCTGGAG
CAGATGTTCCGTGTGGTAGTGGTGCCGATGTACCACCTGATGTGTTGCTACGGCGTGGCGCTAATTGCCCACGGCCAGAA
CATCACTCTGGTAATGAAAGACCATGCCCCCCAGCGCATCCTATTGAAAGATTTCCAGGGCGATATGCGTCTGGTCGATA
AAGATTTTCCACAAGCGGCCTCGCTGCCTAACGTGGTTAAAGACGTGACTGTGCGCTTATCTGCCGACTACCTCATCCAC
GATCTGCAAACCGGCCATTTTGTCACCGTATTACGCTTTATTTCACCGTTGATGCAGGCTTGCAACCTGAGCGAATACCG
CTTCTATCAACTGCTGGCACAGGTGCTGGAGCGCTACATGGCGCAGCATCCAGATTTGGCAGACCGCTTTACCTTATTCA
ATTTATTTAAACCACAGATTATCCGTGTGGTCCTCAACCCAGTAAAACTCACCTACTCAGAGCAGGACGGCGGCAGCCGC
ATGTTGCCTGATTATTTGCAGGATCTGGATAACCCCCTTTATTTGGTCACCAAGGAGCTAGCCCAATGA

Protein sequence :
MITTDYANWQQVNRHMIAKILSELEYERTLHAELHGETGRITLPGAVYTFNGKRGIWGWLHIDPATLRCEGVPLAADHML
RQLALVLKMDDSQVAEHLEDLYATLRGDMQLLSARHGMSAEALIALNDDALQCLLAGHPKFIFNKGRRGWGLTALQHYAP
EYQGQFRLHWVAAKRGSFIWCVDAEYPLDNLLNSAMDPAERQRFDRRWRECQLNDDWVPVPLHPWQWQQKIALHFLPQLA
EGELIELGEFGDHYLAQQSLRTLTNVSRRVPFDIKLPLTIYNTSCYRGIPGKYISAGPAASRWLQQVFAQDRTLHESGAE
ILGEPAAGYMLHQTYATLAKAPYRCQEMLGVIWRENPSCYLREGEHAILMATLMETNNQGHPLIAAYIARSGLSAEAWLE
QMFRVVVVPMYHLMCCYGVALIAHGQNITLVMKDHAPQRILLKDFQGDMRLVDKDFPQAASLPNVVKDVTVRLSADYLIH
DLQTGHFVTVLRFISPLMQACNLSEYRFYQLLAQVLERYMAQHPDLADRFTLFNLFKPQIIRVVLNPVKLTYSEQDGGSR
MLPDYLQDLDNPLYLVTKELAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucC YP_002414044.1 Aerobactin siderophore biosynthesis protein Virulence Not named Protein 0.0 66
iucC AAK71633.1 IucC Virulence SHI-3 Protein 0.0 66
iucC AAD44748.1 IucC Virulence SHI-2 Protein 0.0 66
iucC NP_839221.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 66
iucC NP_709456.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucC NP_670682.1 aerobactin synthetase (subunit beta) VFG1083 Protein 0.0 66
iucC NP_670682.1 aerobactin synthetase (subunit beta) VFG0938 Protein 0.0 66
iucC NP_670682.1 aerobactin synthetase (subunit beta) VFG0617 Protein 0.0 66