Gene Information

Name : iucB (y3382)
Accession : NP_670681.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : acetyl CoA:N6-hydroxylsyine acetyl transferase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1670
EC number : -
Position : 3727395 - 3728345 bp
Length : 951 bp
Strand : +
Note : aerobactin siderophore biosynthesis; residues 5 to 313 of 316 are 65.37 pct identical to residues 4 to 312 of 315 from GenPept : >gb|AAK71632.1|AF335540_4 (AF335540) IucB [Shigella boydii]

DNA sequence :
ATGGGGCCACACGCTAAGTTAATACACTCCGGTGGCAGTTTTTACTGTGAACATCTGGGAAAGGCGCTGACTCTCGGTCT
GGGACTTGATGGCAGTGCCGTACTGCACTTGCCTGGGCCGTTACCGCCAGGTTGGTTGGTGCAAGCACTGGATCAACTGT
TCATCGCCGCACCGCAGTTGACGGGTATTGCCTTGCCGTATGCCGAGTGGCGCGATGCACCACAGGCGATGGCTCTGTTT
GCCTTGATCAGCAGCGACTATGTGGCACGGGAGATATTTTATCAGTTACCGCTGTGGCTGGGTGCAGAACGCAACCGAAC
TGCGGGTCAGATGCAATATGATACCGAGCGGCATCTCTGGTATCCGCAACGCCCGCCCCGCCCAGACGGAGAAGTCTATC
GCCGCTTCGATCCCAACATCAAACGTACCCTGAGTTTCCGGTTACCAGAAGTCGATCACGATGCCCCCCAGTTCACCCGT
TGGATGAACTCACCGCGCGTGGATGCCTTTTGGGAAATGAGCGGCCCACTTGACGTGCAGGCGGCTTATCTGCAACGCCA
GTTAGATTCCCCCTATTGCTACCCGCTGCTGGGATGTTTCGATGATCAACCATTCGGTTATTTCGAAGTGTACTGGGCGG
CGGAAGACCGCATTGGCCGCCACTACCGTTGGCAACCTTTTGACCGCGGTTTGCACATGCTGGTCGGTGAAGAGAACTGG
CGCGGCGCGCAATATATACACAGTTGGTTACGTGGACTGACGCATTATCTGTATCTGGACGAATCGCGCACCACGCGCGT
AGTGGCAGAACCGCGTATTGATAACCAGCGTTTGTTCCACCACCTACCCGCCGCTGGCTACCACACCTTAAAAGAGTTTG
ATTTCCCGCATAAACGTTCGCGTCTGATTATGAATCAACGCGCCGATTTCTTTCGGGAGGGTACACGATGA

Protein sequence :
MGPHAKLIHSGGSFYCEHLGKALTLGLGLDGSAVLHLPGPLPPGWLVQALDQLFIAAPQLTGIALPYAEWRDAPQAMALF
ALISSDYVAREIFYQLPLWLGAERNRTAGQMQYDTERHLWYPQRPPRPDGEVYRRFDPNIKRTLSFRLPEVDHDAPQFTR
WMNSPRVDAFWEMSGPLDVQAAYLQRQLDSPYCYPLLGCFDDQPFGYFEVYWAAEDRIGRHYRWQPFDRGLHMLVGEENW
RGAQYIHSWLRGLTHYLYLDESRTTRVVAEPRIDNQRLFHHLPAAGYHTLKEFDFPHKRSRLIMNQRADFFREGTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucB YP_002414045.1 aerobactin siderophore biosynthesis protein, N(6)-hydroxylysine acetylase Virulence Not named Protein 6e-97 65
iucB NP_839222.1 siderophore biosynthesis protein Virulence SHI-2 Protein 8e-98 65
iucB NP_709455.1 siderophore biosynthesis protein Virulence SHI-2 Protein 8e-98 65
iucB AAD44747.1 IucB Virulence SHI-2 Protein 7e-98 65
iucB AAK71632.1 IucB Virulence SHI-3 Protein 6e-98 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucB NP_670681.1 acetyl CoA:N6-hydroxylsyine acetyl transferase VFG1082 Protein 3e-98 65
iucB NP_670681.1 acetyl CoA:N6-hydroxylsyine acetyl transferase VFG0939 Protein 3e-97 65
iucB NP_670681.1 acetyl CoA:N6-hydroxylsyine acetyl transferase VFG0616 Protein 3e-98 65