Gene Information

Name : clpB (y3362)
Accession : NP_670661.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3705087 - 3707735 bp
Length : 2649 bp
Strand : -
Note : similarities to ClpB protease; residues 1 to 856 of 882 are 48.37 pct identical to residues 1 to 883 of 905 from GenPept : >emb|CAD17900.1| (AL646080) ClpA/B-type chaperone protein [Ralstonia solanacearum]

DNA sequence :
ATGACAACGCATTCAGCACACTTATTACGCCGCTTAAATCCCTATTGCGCACAGGCACTGGCCGGTGCTGCCACCCTGTG
TCAGACCCGCGCCCATGCCGAGATCACTGTCGAACACTGGTTGTTAAAACTGCTGGAGCAGGGCGAAGGCGATATCACGG
TGATTGCCCGGCGTTATGAGTGGGACATGGACAGCTTGTGGCAAGGGTTACTGGCCTATCTGGATACTTTGCCGCGCACG
GTACAGGGTAAACCCCAACTGTCCGCCGCGTTGCAGCAACTGATCAAAAGTGCCTGGCTGGATGCCTCGTTGCAGGAAAA
TGCTGATGCGGTGCGCTCGGTTCATCTAATGGCAGCGCTGATAAATTCGCCATCATTATTGGCCGCCGATGCCGCCTGGC
CGTTGCTCAGCCTGAGCACTACCCAACTACACCGCTTGTTGCCGTTGCTGGACAGCCAATCCGACGAACGCCCTGAAATA
CAGCAGGCCGCAGCACTGGCAGACAGCCCGGTCAATCTGACCGATGAGGCCGCGACGGTTACCTCCGCCAGTGGTCAGCC
GCAACTGAATGACGCGCTGCAAGCGGCGCTGGATAAATTTACCCTCGATGTCACCGCCAAAGCCCGTGCCAACCAGATTG
ATCCGATTTTTGGCCGCGACAGCGAAATCCGCCAGATGATCGACATCCTGTCGCGCCGCCGTAAAAACAACCCGATTTTG
GTGGGTGAACCGGGTGTGGGGAAAACCGCCTTGGTTGAAGGGCTGGCACTGCGCATTGCCGAGGGCAACGTACCGGACAG
CCTGAAAACCGTCAGTGTGCGCACACTGGATTTGGGTCTGTTACAGGCCGGTGCCGGGGTCAAAGGCGAGTTCGAACAGC
GCCTGAAAAATGTTATCGAGGCGGTGCAACAATCCCCCAGCCCGGTGCTGCTGTTTATCGACGAAGCCCACACCATTATC
GGGGCCGGTAATCAGGCCGGTGGTGCCGATGCGGCCAACCTGCTGAAACCGGCACTGGCGCGTGGCGAACTGCGCACCAT
CGCCGCCACCACCTGGTCCGAATACAAACAGTATTTTGAACGCGATGCCGCACTGGAGCGCCGCTTCCAGATGGTCAAAG
TGGACGAGCCGGATGATGACACCGCCTGCCTGATGCTGCGTGGCCTGAAAGAACGTTACGCCACCCATCACGGCGTGCAT
ATTCTGGACGCCGCTATCACCGCAGCGGTTACCCTGTCGCGCCGCTTCCTGACCGGCCGCCAACTGCCGGACAAAGCGGT
GGATCTGCTCGATACCGCCGGTGCCCGGGTGCGCATGAGCATTGACACCTTGCCGACTGCGCTGATGGCGATTAACGCCG
AGCTGGCCGCACTGGCGATGGAGCAACAGGCCATCGAACAGGACCTGCTCCTGCTGCCGAATGTCAGTTCAACGCGCTTA
CCTGAGATTGAGCAACGCCGCGCCGCGCTGGCGGTTGGGCAGCACACACTCGAACAGCAATATAAAGAAGAAAAACGGCT
GACCACCCTGATTATCGAGGCGCGTCAGGATATCGCCAACGTGGCACATCTGGTCGCGTTGCAGGAGGAACTCGTTCAGA
TCCAAGGCAACGCGCCGCTGCTGTCGCTGGACGTTGATGTGCGCACTGTTGCGGCTGTGATCGCCGACTGGACCGGCGTG
CCGCTGAGCAGTCTGTTGAAAGACGAACAGACCGATTTGTTGCAACTGGAAAACCATCTCGCCACCCGCGTAGTCGGGCA
GGATACGGCGCTGGGTGCGCTGGCGCAACGGCTGCGGGCGGCGAAAACCGGGCTGACATCAGAGAATGGCCCGCTGGGGG
TGTTCCTGCTGGTCGGGCCGAGTGGGATCGGCAAAACCGAAACCGCGCTGGCACTGGCCGACAGCCTGTTCGGCGGCGAG
AAATCGCTGATCACCATCAACTTATCGGAGTATCAGGAAGCTCACACCGTCTCCCAGTTGAAAGGGTCGCCCCCAGGTTA
TGTTGGCTACGGTCAGGGTGGTGTATTAACCGAAGCGGTACGTAAACGGCCTTACAGCGTGGTGCTGCTGGATGAAGTGG
AAAAAGCCCATCGTGATGTGCTGAACCTGTTCTATCAGGTGTTTGACCGGGGGTTCATGCGCGACGGTGAAGGGCGCGAA
ATTGATTTTCGTAACACAGTGATCCTAATGACGGCCAATTTAGGCAGTGATCATCTGATGCAGTTACTGGATGAACAACC
GGAAGCGACGCACAGTGATTTACACGAGCTGCTGCGCCCGATCCTGCGCGATCATTTCCAGCCCGCGCTATTAGCCCGCT
TCCAGACCTTGATCTACCGCCCACTGAATGCCATCGCATTGCGCACCATCGTCGAGATGAAACTGGCACAGGTCGCTAAA
CGCCTGAACAAACATTACGGCCTGCACTGCACCATTGAGGAAAGCCTCTACGACACACTGGTCGCCGCCTGCCTGCTGCC
GGACACCGGCGCACGCAACATCGACAGCCTGCTCAATCAACAAATCTTACCGGTATTGAGCCAGCAGCTGTTAAGCCGCA
TGAGCGAGCAACAGCGCACCACCTCGCTGACGCTGGGCTGGGATGAAGCCGACGGCATTACCCTTGAATTTGAAGGAGGC
GAAAAATGA

Protein sequence :
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLAYLDTLPRT
VQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEI
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIAEGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVH
ILDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGV
PLSSLLKDEQTDLLQLENHLATRVVGQDTALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGE
KSLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
IDFRNTVILMTANLGSDHLMQLLDEQPEATHSDLHELLRPILRDHFQPALLARFQTLIYRPLNAIALRTIVEMKLAQVAK
RLNKHYGLHCTIEESLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGG
EK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-136 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_670661.1 protease VFG2084 Protein 8e-136 44
clpB NP_670661.1 protease VFG2076 Protein 5e-151 43