Gene Information

Name : serS (y2796)
Accession : NP_670096.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 3095713 - 3097005 bp
Length : 1293 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATCCCAATATGCTGCGCAATGAGCTAGACGCAGTCGCCGAAAAACTGGCTCGCAGAGGTTTTAAACTTGATGT
TGAGGTGTTGCGCCAACAAGAAGAGCGCCGCAAAGTTTTACAGGTTGAAACAGAAAGTCTGCAGGCAGAACGTAACTCCC
GATCGAAACAGATCGGTGCAGCAAAGGCGCGTGGCGAAGATATCGAACCATTACGTCTGGAAGTGAATGCTCTGGGTGAA
AAACTGGATGCCGCTAAAGCTGAGTTGGATAAGTTACAAAACGAAATCCGCGATTTAGCGCTGTCTATCCCTAATCTGCC
AGATGATTCAGTACCGGTAGGTAAAAACGAGAATGACAATATTGAAGTCAGTCGGTGGGGCGAGCCTCGCAAATATGACT
TCGACGTAAAAGATCATGTTTCTCTGGGCGAAATGGCCGGTGGCCTTGATTTTGCTGCCGCTGTGAAACTGACCGGCGCA
CGCTTTGTGGTGATGAAAGGGCAAATTGCCCGTATGCACCGTGCTCTGTCTCAGTTCATGTTAGACCTGCACACCGAGAA
ACACGGTTATCTGGAAGCTTACGTCCCTTATCTGGTTAATCATGCCACCTTGTACGGTACGGGTCAGTTACCCAAGTTTG
GTGAAGATCTATTCCATACTAAACCGTTGGCAGAAGAATCAGATAACAGTAACTATGCTTTGATTCCTACTGCTGAAGTT
CCGCTGACCAACTTGGTGCGCGATGAAATTTTGGAAGAGGATTCTCTGCCATTGAAGTTGACCGCCCATACACCATGCTT
CCGTTCTGAAGCAGGTTCCTATGGCCGTGATACCCGTGGTTTGATCCGGATGCATCAATTCGACAAAGTTGAAATGGTGC
AGATCACTCGTCCGGAAGATTCTATGGCCGCGCTGGAAGAGTTGACAGGGCACGCCGAGAAAGTTCTGCAATTACTGGAG
TTGCCATACCGCAAGGTATTGCTGTGTACGGGTGATATGGGCTTTGGCTCCAGCAAAACTTACGATCTGGAAGTATGGTT
GCCAGCACAGGACACTTACCGCGAAATATCCTCATGTTCTAACATGTGGGATTTCCAGGCGCGCCGTATGCAGGCCCGTT
ATCGCAACAAGACCGACAGAAAGACGCGTTTAGTGCACACGCTGAACGGCTCTGGTTTGGCGGTTGGGCGTACCTTGGTA
GCGGTGTTGGAAAACTATCAACAGGCAGATGGTCGTATCCAGGTCCCTGACGTATTACGTCCATATATGGGTGGCTTGGA
ATATATTGGTTAA

Protein sequence :
MLDPNMLRNELDAVAEKLARRGFKLDVEVLRQQEERRKVLQVETESLQAERNSRSKQIGAAKARGEDIEPLRLEVNALGE
KLDAAKAELDKLQNEIRDLALSIPNLPDDSVPVGKNENDNIEVSRWGEPRKYDFDVKDHVSLGEMAGGLDFAAAVKLTGA
RFVVMKGQIARMHRALSQFMLDLHTEKHGYLEAYVPYLVNHATLYGTGQLPKFGEDLFHTKPLAEESDNSNYALIPTAEV
PLTNLVRDEILEEDSLPLKLTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQITRPEDSMAALEELTGHAEKVLQLLE
LPYRKVLLCTGDMGFGSSKTYDLEVWLPAQDTYREISSCSNMWDFQARRMQARYRNKTDRKTRLVHTLNGSGLAVGRTLV
AVLENYQQADGRIQVPDVLRPYMGGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-108 55