Gene Information

Name : clpB (y2699)
Accession : NP_670001.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : heat shock protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2981840 - 2984479 bp
Length : 2640 bp
Strand : -
Note : residues 196 to 851 of 879 are 43.63 pct identical to residues 160 to 835 of 857 from E. coli K12 : B2592; residues 1 to 855 of 879 are 48.82 pct identical to residues 1 to 883 of 905 from GenPept : >emb|CAD17900.1| (AL646080) ClpA/B-type chaperone protei

DNA sequence :
ATGACAACGCATTCAGCACACTTATTACGTCGGTTAAATCCCTATTGCGCACAGGCACTGGCCGGTGCCGCCACCCTGTG
TCAGACCCGCGCCCATGCTGAGATCACTGTCGAACACTGGTTGTTAAAATTGCTGGAGCAGGGCGAAGGCGATATTACAG
TCATTGCCCGGCGTTATGAGTGGGACATGGACAGCCTGTGGCAGGGATTACTGTCCCATCTGGACACCTTGCCGCGCACG
GTACAGGGCAAACCTCAGTTGTCCGCCGCGTTACAGCAACTGATCAAAAACGCCTGGCTGGATGCCTCGTTGCAGGAAAA
TGCTGATGCGGTGCGCTCGGTTCATCTAATGGCAGCGCTGATTGCCACGCCGTCATTATTGGTCGCCGAGGCCGCCTGGC
CGTTGCTCAGCCTGAGCACCACTCAGCTACAGCGCCTGTTACCGCTGCTGGACAACCAGTCCGACGAACGCCCTGAGGTG
CAGCAGGCTGCGGCACTGGCCGACAGCCCGGTCAATCTGACCGATGAGGCCGCGACGGTTACCTCCGCCAGTGGTCAGCC
GCAACTGAATGACGCGCTGCAAGCGGCGCTGGATAAATTCACCCTCGACGTCACCGCCAAAGCCCGTGCCAACCAGATTG
ACCCGATTTTTGGCCGCGACAGCGAAATCCGCCAGATGATCGACATCCTGTCGCGCCGCCGTAAAAACAACCCGATTCTG
GTGGGTGAACCGGGTGTGGGGAAAACCGCGCTGGTTGAAGGGCTGGCACTGCGGATTGCCGACGGCAACGTACCGGACAG
CCTGAAAACCGTCAGTGTGCGCACACTGGATTTGGGTCTGTTACAGGCCGGGGCTGGGGTGAAAGGCGAATTCGAACAGC
GCCTGAAAAATGTTATCGAGGCGGTGCAACAATCCCCCAGCCCGGTGCTGCTGTTTATCGACGAAGCCCACACCATTATC
GGGGCCGGTAATCAGGCCGGTGGTGCCGATGCGGCCAACCTGCTGAAACCTGCACTGGCGCGTGGCGAACTGCGCACCAT
CGCCGCCACCTGGTCCGAATACAAACAGTATTTTGAACGCGATGCCGCACTGGAGCGCCGCTTCCAGATGGTCAAAGTGG
ACGAGCCGGATGATGACACCGCCTGCCTGATGCTGCGTGGCCTGAAAGAACGTTACGCCACCCATCACGGCGTGCATATT
CTGGACGCCGCTATCACCGCAGCGGTTACCCTGTCGCGCCGCTTTCTGACCGGTCGCCAACTGCCGGACAAAGCGGTGGA
TCTTCTCGACACCGCAGGTGCGCGCGTGCGCATGAGCATCGACACCTTGCCGACTGCGTTGATGGAGATTAACGCCGAAC
TGGCCGCACTGGCGATGGAGCAACAGGCCATCGAACAGGACTTGCTCCTGCTGCCGAATGTCAGTTCAACGCGCTTACCT
GAGATTGAGCAACGCCGCGCCGCGCTGGCGGTTGGGCAGCACACACTCGAACAGCAATATAAAGAAGAGAAGCGGTTGAC
CACCCTGATTATTGAGGCGCGTCAGGACATCGCCAACGCAGCACATCTGGTCGCGTTGCAGGAGGAACTCGTTCAGATTC
AGGGCAATGCGCCGCTGTTGTCGCTGGACGTTGATGTGCGCACTGTTGCGGCTGTGATCGCCGACTGGACCGGTGTGCCG
CTGGGCAGTTTACTCAAAGACGAACAAACCAACTTGCTGTCACTGGAAAATCGTCTGGGTGAGCGAGTGATTGGGCAGGA
TGCGGCATTAGGTGCGCTGGCGCAACGGCTGCGGGCCGCCAAAACCGGCCTGACATCAGAGAATGGCCCGCTGGGGGTGT
TCCTGCTGGTCGGGCCGAGTGGGATCGGCAAAACCGAAACCGCGTTGGCACTGGCCGACAGCCTGTTCGGCGGGGAAAAA
TCGCTGATCACCATCAACTTATCGGAGTATCAGGAAGCGCACACCGTCTCCCAGTTGAAAGGGTCGCCCCCGGGTTATGT
CGGTTACGGACAGGGCGGCGTATTAACCGAAGCGGTACGTAAACGGCCTTACAGCGTGGTGCTGCTGGATGAAGTGGAAA
AAGCCCATCGTGATGTGCTGAACCTGTTCTATCAGGTGTTTGACCGGGGGTTCATGCGCGACGGTGAAGGGCGCGAAATT
GATTTCCGCAACACGGTCATTGTGATGACCGCCAATCTGGGCAGTGATCATCTGATGCAGTTGCTGGATGAGCAACCGGA
CGCGCCGGACAGCACCCTGCATGAACTGCTGCGGCCGATCCTACGCGACCACTTCCAGCCCGCGCTGCTGGCCCGCTTCC
AGACCTTGATTTACCGCCCGCTTCAGGTGGATGCGCTCAAACGCATTGTGGCGATAAAACTGAATCAGGTGGCGCAACGC
CTGCACTGTCACTACGGCCTGAGCTGCCAGATTGAAGACAGCCTGACCGACACACTGGTCGCCGCCTGCCTGCTGCCGGA
CACCGGCGCACGCAACATCGACAGCCTGCTCAATCAGCAGATTTTACCGGTATTGAGCCAGCAGCTGTTAAGCCGCATGA
GCGAGCAACAGCGCACCACCTCGCTGACGCTGGGCTGGCATGAAGAAGATGGCATCACGCTGACATTTGAGGGCGAATAA

Protein sequence :
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRT
VQGKPQLSAALQQLIKNAWLDASLQENADAVRSVHLMAALIATPSLLVAEAAWPLLSLSTTQLQRLLPLLDNQSDERPEV
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHI
LDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMEINAELAALAMEQQAIEQDLLLLPNVSSTRLP
EIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANAAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGVP
LGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEK
SLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREI
DFRNTVIVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLQVDALKRIVAIKLNQVAQR
LHCHYGLSCQIEDSLTDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWHEEDGITLTFEGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-129 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_670001.1 heat shock protein VFG2084 Protein 2e-128 43
clpB NP_670001.1 heat shock protein VFG2076 Protein 3e-145 43